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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Introduction

(Consensus based Risk Staging System (CRSS) calculator for Multiple Myeloma (Version 1.0)

Link:- 

http://sbilab.iiitd.edu.in/pub_files/CRRScalculator_edit.html

 Link : https://aiims.edu/index.php/en/publications_drritu_lab_oncology

Prof. Ritu Gupta, MD, FRCPath, is Professor and Head of the Department of Onco-Haematopathology at the All India Institute of Medical Sciences (AIIMS), New Delhi. She is a leading hematopathologist with over two decades of experience in diagnostic hematopathology, translational hemato-oncology, and precision diagnostics. Her work bridges clinical practice and research through the application of advanced flow cytometry, genomics, digital pathology and artificial intelligence, and emerging technologies for the diagnosis, prognostication, and monitoring of haematological malignancies. She is a member of the Central Core Research Facility (CCRF) of AIIMS and has contributed particularly in the development of the Genomics and Flow cytometry facilities of the CCRF.

Prof. Gupta’s laboratory is a pioneer, has established several hematological investigations of clinical relevance and state-of-the-art technologies such as single cell analysis and next generation sequencing. She has established minimal residual disease estimation, IGHV somatic mutation detection and molecular characterization of blood cancers using varied molecular methods including Next generation sequencing. Few of the research outputs include development of deep learning based indigenous risk stratification models specific for Indian patients with multiple myeloma, deciphering the process of clonal evolution and epigenetic and genetic biomarkers of prognostic relevance. Considering the challenges in detecting low levels of residual malignant cells, her laboratory is engaged in validating image processing modules for minimal residual disease detection. 

Prof. Gupta has earned international recognition for her pioneering work in clinical hematopathology, translational cancer research, and academic leadership. She holds Fellowships in key scientific and professional organizations, including the Indian Academy of Sciences (FASc), the National Academy of Sciences, India (FNASc), and the National Academy of Medical Sciences (FAMS).

Areas of Interest

  • Immunophenotyping, Genomics and proteomics of Haematological malignancies

  • Oncogenesis and Cancer biomarkers discovery

  • Innovations in Digital Hematopathology and Artificial Intelligence

Significant Contributions

  • Established and led the development of India’s first fully robotic, high-throughput clinical laboratory at the National Cancer Institute (NCI), Jhajjar, AIIMS.

  • Lead, Unit of Excellence for Cancer Research in Multiple Myeloma, AIIMS, Delhi

  • Lead, Centre of Advanced Research and Excellence in Acute Myeloid Leukemia, AIIMS, Delhi

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