Dr. Mona Sharma   MD, DNB, MAMS      

                                            Associate Professor                                                

Department of Reproductive Biology,

Room no. 2087, 2^nd Floor, Teaching Block

                                 AIIMS, New Delhi                                      

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

9968147821

 

PROFESSIONAL QUALIFICATION:                                                     

1. DNB (Anatomy) from National Board of Examinations in 2013.
2. MD (Anatomy) from All India Institute of Medical Sciences (AIIMS), New Delhi in May, 2009
3. MBBS from Kasturba Medical College, MAHE, Mangalore, Karnataka in 2003.

 

EMPLOYMENT DETAILS  

1. Associate Professor in the Department of Reproductive Biology from July 1, 2017 till date.
2. Assistant Professor in the Department of Reproductive Biology from May 23, 2014 to June 30 2017. 
3. Assistant Professor at Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi from September 25, 2012 to May 22, 2014.
4. Senior Residency at AIIMS, New Delhi from June 12, 2009 to June 11, 2012.

 

RESEARCH WORK  

1. Principal investigator: High Resolution Sex Chromosome Genome Analysis in Pathogenesis of Premature Ovarian Failure (A-360).
2. Principal investigator: Study of potential sperm factors and related signaling pathways in eliciting oocyte intracellular calcium rise (A-631).
3. Chief-guide: Mutational Analysis of HS6ST2: A Candidate Gene in Idiopathic Premature Ovarian Failure.
4. Chief-guide: Effect of L-acetyl carnitine on TNF-α Induced Apoptosis in mice follicles.
5. Chief-guide: Citrate synthase expression in human sperm and oocyte activation in mice.
6. Chief-guide: Role of L-carnitine in oocyte activation.
7. Chief-guide: Effect of sperm vitrification on PLC-zeta expression.
8. Co-guide: Epigenetic changes during epithelial to mesenchymal transition in trophoblast cells under physiological and pathological conditions.
9. Co-guide: A correlative study of feto-maternal hydrogen sulfide production with umbilical artery velocimetry in preeclampsia.
10. Co-guide:  Pre and post-vasectomy sperm parameters.
11. Co-guide: Effect of tyrosine kinase inhibitors on sperm parameters and pituitary gonadal axis in males with chronic myelois leukemia.
12. Co-guide: Etiopathology of hyperprolactinemia.
13. Co-guide: Biomarkers in polycystic ovarian syndrome.
14. Co-guide: Genomics and epigenomics of polycystic ovarian syndrome
15. Co-guide: Role of placental derived exosomes in decidualization in recurrent pregnancy loss patients
16. Co-guide: Genetic determinants of premature ovarian failure patients.
17. Thesis research: “Apoptosis in Trophoblastic Cells of Human Placenta in Preeclampsia”
18. DC member: Role of micro RNA-30 in cystathionine gamma lyase mediated trophoblast cell invasion and status in preeclampsia.
19. DC member: To elucidate the role of osteoimmune system in regulating fertility
20. DC member: Delineating the role of insulin/insulin like growth factor signaling in C.elegans reproductive aging.
21. DC member: HDAC inhibitors mediated genome-wide dynamics in c.elegans embryogenesis and aging.
22. DC member: Characterization of TEX29 protein and its potential role in mammalian fertilization.
23. Embryological basis of anatomical variations in humans as part of UG, PG teaching program. 

 

PROJECTS

AIIMS intramural research funding:

Completed: Intramural project titled “High Resolution Sex Chromosome Genome Analysis in pathogenesis of Premature Ovarian Failure” (array cGH)

Ongoing: Intramural project titled “Study of potential sperm factors and related signaling pathways in eliciting oocyte intracellular calcium rise.” (Heterologous ICSI) 

Technically approved” Role of mitochondrial fatty acid shuttle system in premature ovarian failure”DHR/GIA

 

PUBLICATIONS  

1. Asuri K, Mohammad A, Prajapati OP, Sagar R, Kumar A, Sharma M, Chaturvedi PK, Gupta SV, Rai SK, Misra MC, Bansal VK. A prospective randomized comparison of sexual function and semen analysis following laparoscopic totally extraperitoneal (TEP) and transabdominal pre‑peritoneal (TAPP) inguinal hernia repair. Surg.endo.2020. https://doi.org/10.1007/s00464-020-07733-y
2. Rishi I, Halder A, Sharma JB, Jain M and Sharma M. Single Strand Conformation Polymorphism and sequencing to detect HS6ST2 gene mutations in patients of idiopathic premature ovarian failure.JCDR; Jan 2020:1-9.
3. Sharma Y, Sharma M. Sperm Cryopreservation: Principles and Biology. Accepted for publication in Journal of infertility and Reproductive biology, 2020.
4. Sharma M. Assisted oocyte activation. March 2019; Indian Fertility Society.
5. Sharma M. Recent evidence for PGS/PGD; July 2019; Indian Fertility Society.
6. Sharma M. Oocyte Activation following Intracytoplasmic Sperm Injection: Current Status from Bench to Bedside; 2019; Indian Society for the study of Reproduction and Fertility.
7. Kumar A, Sharma M. Basics of Human Andrology. 1^st ed. Springer Nature, Singapore. 2017; 1-536.
8. Sharma M, Gupta S, Dhole B, Kumar A. The Prostate gland. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 17-35
9. Gupta S, Sharma M, Kumar A. Seminal Vesicles. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 37-45.
10. Sharma M, Kumar A. Neurovascular supply and lymphatic drainage of male reproductive organs. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 55-65.
11. Sharma M, Kumar A. The Sperm. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 171-203.
12. Sharma M, Kumar A. Male Sexual Function. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 251-281.
13. Sharma M, Chadda RK, Anish PK,  Kumar A. Male Behaviors I: Brain areas regulating male behaviors. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 293-313.
14. Sharma M, Kumar A. Male II: Neural pathways regulating male behaviors Behaviors. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 315-339.
15. Sharma M, Kumar A. Male Behaviors III: Brain polymorphism and sexual orientation. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 341-347.
16. Sharma M, Kumar A. Male Behaviors IV: Ageing brain. In: Basics of Human Andrology, 1^st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 349-362.
17. Shivi Goel, Jyoti Arora, Vandana Mehta, Mona Sharma, Rajesh Kumar Suri and Gayatri Rath. Unusual disposition of lateral circumflex femoral artery – anatomical description and clinical implications. World J Clin Cases 2015 January 16; 3(1): 85-88.
18. R. Hansdak, J. Arora, M. Sharma, V. Mehta, R K Suri, S. Das. Unusual branching pattern of brachial artery-Embryological basis and clinicoanatomical insight. La Clinica Terapeutica,March 2015, 166: 2;65-7.
19. Shivi Goel, Jyoti Arora, Vandana Mehta, Mona Sharma, Rajesh Kumar Suri and Gayatri Rath, Das S. Adductor accessorius- an unusual supernumerary adductor muscles of thigh. La Clinica Terapeutica, 2015, May-Jun;166 (3): 117-7.
20. Rustagi SM, Sharma M, Singh N, Mehta V, Suri R, Rath G. Peripheral communications   of the Intercostobrachial Nerve in relation to the Alar Thoracic Artery. Advanced Medical Research, Feb 2015, 1-4.
21. Gandhi S, Sharma M, Pakhiddey R, Thakur A, Mehta V, Suri R, Rath G. Unduly extensive uncinate process of pancreas in conjunction with pancreatico- duodenal fold. Anat Cell Biol, March 2015; 48: 81-83. 
22. Sharma M, Hansdak R, Mehta V, Arora J, Suri R, Rath G. An unusual branching pattern of the median cubital vein and its relations with lateral cutaneous nerve of forearm in the upper extremity-anatomicoclinical notes. JSA, 2014 (4)1:49-53. 
23. Mona S, Renu D. Possible developmental origin and clinical implications of a brachial plexus variation. GJRA; 3(2): 60-62, 2014. 
24. Thakur A, Tapas S, Sharma M, Mehta V, Suri R, Rath G. Anatomical description of a variant abductor digiti minimi accessorious muscle and its clinical correlation with ulnar neurovascular entrapment syndrome. Journal of Surgical Academia 2014; 4(2):41-44. 
25. Sharma M, Kumar R, Dhingra R. “Apoptosis: Researching the clinical implications”. JIMSA July-Sept. 2014;27(3). 
26. Gandhi S, Sharma M, Pakhiddey R, Mehta V, Suri RK, Rath G. “Unilateral aberrant gonadal venous anatomy coexistent with a distinct intrarenal cleft”. OA Anatomy 2013 Nov 01;1(3):28.
27. Sharma M, Kumar R, Bhatla N, Dhingra R. "A Comparative study of apoptosis in placentas of normal and preeclamptic Indian pregnant women by TUNEL assay and M30 immunostaining.  Journal of clinical laboratory analysis; 2012: 26: 459-466.
28. Sharma M, Kumar R, Dhingra R. “An immunohistochemical study of the syncytial knots in the preeclamptic placentas". International journal of pharmaceutical research and bioscience; 2012: 1(4) 228-239.
29. Sharma M, Dhingra R, Kumar R. “Relevance of placental pathological changes of maternal inflammatory syndrome along with the obstetric and clinical parameters in preeclampsia”. International journal of scientific and research publications, 2012; 2(8): 313-320.
30. Sharma M, Kumar R, Dhingra R. “Apoptosis: Understanding of the signaling pathways”. International journal of biological and medical research. 2012; 3(3):2029--2031.
31. Sharma M, Kumar R, Dhingra R. “Apoptosis: Searching for the detection techniques”. International journal of biological and medical research. 2012; 3(3):2172-2175.

 

AWARDS AND ACHIEVEMENTS

Best Poster Award for paper titled “Role of l-carnitine in TNF-α induced mice oocyte apoptosis” Rana R, Halder A, Sharma M; at ISSRF World congress,  February 2020 at ICMR-SMVDU, Centre for Advanced Research, SMVDU, Katra. Jammu & Kashmir, India

Best Poster Award for paper titled“Evaluation of Parameters to Standardize Single Strand Conformation Polymorphism for Detecting Gene Mutations in Patients of Idiopathic Premature Ovarian Failure”.  Isha Rishi, J B Sharma, Manish Jain, Mona Sharma,  at ISSRF, 2019, JNU, New Delhi

Elected as member of National Academy of Medical Sciences

Reviewer of a book proposal titled “Molecular mechanisms in spermatogenesis and male infertility” submitted to CRC Press. 

Reviewer of a book proposal titled “Thyroid and human reproductive functions” submitted to CRC Press.

DBT project reviewer

Editor, Indian Fertility Society, Newsletter “ReproGenQ”

Memberships :

Academy of Clinical Embryologists

Indian Fertility Society

Endocrine Society of India

Indian Society for the Study of Reproduction and Fertility

Society for Reproductive Biology and Comparative Endocrinology 

Invited Talks

1. Guest Lecture: “Puberty awareness”. In CME on child abuse, held on 12-11-19 in AIIMS, New Delhi
2. Guest lecture on “Recent advances in infertility” on November 11, 2018 during 66^th NATCON-ASI at AIIMS Rishikesh
3. Guest Lecture on “Non invasive methods of preimplantation and prenatal diagnosis” on 4^th April 2015 in the Department of Anatomy, VMMC & Safdarjung hospital, New Delhi.