Clinical Pharmacology Facility:
As an extension of the Department of Pharmacology, a newly constructed wing in New Private Ward building was taken up as ‘Clinical Pharmacology Wing’ by Department of Pharmacology in collaboration with Forensic Medicine to upscale patient care facilities and in-patient wards for various clinical pharmacology activities.
Therapeutic Drug Monitoring Facility:
Therapeutic drug monitoring has become important for dose titration of many drugs of narrow therapeutic margin. Interpretation of TDM results should also take into consideration time of sample in relation to last dose, duration of treatment with the current dose, dosing schedule, age, gender, concomitant drug therapy, relevant disease states, reason for request e.g. lack of effect, routine monitoring, suspected toxicity, the patient’s response and the desired clinical target. It is important to remember that drug concentrations need to be interpreted in the context of the individual patient without rigid adherence to a therapeutic range.
The Department of Pharmacology in collaboration with the Department of Nephrology at All India Institute of Medical Sciences, has started therapeutic drug monitoring facility of several drugs for patient care and research. To start with, antiepileptic drugs, immunosuppressants like cyclosporine, and methotrexate have been started for patient for patient care free of cost.
In the year 2007-2008, the following samples were from different departments were done for patients free of cost:
LH – 35 patients
FSH 7 patients
E2 38 patients
Progesterone- 4 patients
Prolactin- 1 patient
Valproate- 65 patients
ii. PCR apparatus
iii. Laminar flow cabinet
iv. Western blot assembly
v. CO2 Incubator
vi. Inverted microscopes
vii. Water purification system
ix. Atomic absorption spectroscopy
x. Biopac System for EGG measurement.
xiii. Deep freezer (-20oC)
xiv. Deep freezer (-70oC)
xvi. PH meter
xvii. Hot Water Bath