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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi
कॉल सेंटर:  011-26589142

Alumni

Dr. Lalit Dar

 

 

 

 

 

 

Dr. Lalit Dar

Professor

Department of Microbiology

यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

 

Dr. Lalit Dar is a Professor in the Department of Microbiology, All India Institute of Medical Sciences, Delhi, and heads the virology section of the Department. After completing his MBBS from the Maulana Azad Medical College, Delhi University, he obtained an MD degree in Microbiology from AIIMS. He has been working as a faculty member in the Virology Section since 1994.

In addition to classical virology, Dr. Dar is well-versed in molecular biology and immunology. His major area of interest is virology, particularly arthropod- borne viruses (dengue, chikungunya), viruses that affect maternal and child health (HPV, cytomegalovirus and HIV) and respiratory viruses (Influenza, SARS Coronavirus-2). He has completed various projects in these areas, with extramural funding from Indian Council of Medical Research, Department of Biotechnology and the National AIDS Control Organization (NACO).

 

Dr. Dar has more than 100 publications in national and international journals and books. The virology laboratory at AIIMS is a state-of-the-art laboratory, providing a wide range of tests in clinical diagnostic virology, from cell culture for viruses, to serology and nucleic acid tests. The laboratory is a part of the Indian Council of Medical Research (ICMR) network for influenza surveillance; a National Vector Borne Disease Control Programme (NVBDCP) Apex laboratory for Dengue and Chikungunya, as well as a NACO Referral Laboratory for Early Infant Diagnosis of HIV for various Indian states. The laboratory has collaborated on projects with various foreign universities (Johns Hopkins University, University of Alabama at Birmingham, University of California at Los Angeles, University of Michigan at Ann Arbor- Arizona State University), as well as conducted collaborative projects with joint funding from ICMR along with the National Institutes of Health (NIH) and Centers of Disease Control (CDC).

Dr. Dar is also a trained laboratory assessor (ISO15189) and a member of the advisory accreditation committee of the National Accreditation Board for Testing and Calibration Laboratories (NABL). He is a recipient of the Fogarty Fellowship of the National Institutes of Health (NIH), USA. He has provided technical expertise and consultancy for the communicable diseases and molecular biology related activities of the International Atomic Energy Agency (IAEA), United Nations, for over a decade. He is a member of the project review committee of ICMR for virology and of the technical resource group of NACO for laboratories.

 

 

 

 

 

 

Dr. Benu Dhawan

 

 

 

 

 

Dr. Benu Dhawan

Professor

Department of Microbiology

E-mail:  यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

 

Dr. Benu Dhawan graduated in Medicine from Government Medical College, Patiala, in 1987. She obtained her MD (Microbiology) degree from the Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh in 1993. She joined the All India Institute of Medical Sciences, New Delhi in the year 1994. She is presently a Professor in the Bacteriology & Mycoplasma division of the Department of Microbiology.

Research Focus:

1. Sexually Transmitted Infections with special reference to Genital Mycoplasmas and Chlamydia trachomatis

2. Diagnostic Microbiology with special reference to Prosthetic Joint Infections

3. Molecular epidemiology and antimicrobial resistance of nosocomial pathogens with special reference to Staphylococci and Enterococci.

Research Guidance (Chief Guide)

Ph.D:                                                   5

M.D./M.S.:                                          6

D.M. (Infectious Diseases:     1

Publications

Research papers published: 168

           Cumulated citation index (CI): 3237       Cumulated Impact Factor (IF): 373.194

       Chapter in Books                    : 1

 

International Awards and Honours

1        Congress Scholarship by the German foundation for International Development (DSE), 1998.

2        Nominated as “2002 Woman of the Year” by the American Biographical Institute

3        Awarded the “2003 Certificate of Membership to the American Association for the Advancement of Science ’’

4        Recipient of Honorable Mention to the ASM-UNESCO Train-the-Trainers Scholarship Program, 2008.

 

Selected publications:

  1. Rao C, *Dhawan B, Vishnubhatla S, Kapil A, Das B, Sood S. Clinical and Molecular Epidemiology of Vancomycin-resistant Enterococcus faecium Bacteremia from an Indian Tertiary Hospital. Eur J Clin Microbiol Infect Dis. 2021 Feb; 40(2):303-314.
  2. Dhawan B, Rawre J, Dhawan N, Bhatia R, Gupta V, Khanna N. High Prevalence of Mycoplasma genitalium in men who have sex with men: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2020 Mar-Apr; 86(2):195-196.
  3. Rawre J, *Dhawan B, Khanna N, Sreenivas V, Broor S, Chaudhry R. Distribution of Chlamydia trachomatis omp A genotypes in patients attending a sexually transmitted disease outpatient clinic in New Delhi, India. Indian Journal of Medical Research. 2019 May 1; 149(5):662. IF: 1.503; CI:2
  4. Sebastian S, Malhotra R, Dhawan B, Sreenivas V, Kapil A, Chaudhry R. Sonication of antibiotic loaded cement spacers: A valuable technique for detection of infection persistence in two-stage revision for infected joint arthroplasty. Indian J Med Microbiol. 2019; 37:99-10.
  5. Sebastian S, Malhotra R, Sreenivas V, Kapil A, Chaudhry R, *Dhawan B. A clinico-microbiological study of prosthetic joint infections in an Indian tertiary care hospital: Role of Universal 16S rRNA gene polymerase chain reaction and sequencing in diagnosis. Indian J Orthop. 2019; 53:646-54.

 

 

 

 

 

 

 

Dr. Urvashi B Singh

 

 

 

 

 

Dr. Urvashi B Singh MD, PhD, FAMS

Professor, In-Charge, Tuberculosis Division, Department of Microbiology,

All India Institute of Medical Sciences, (AIIMS), New Delhi

 

Dr Urvashi B Singh’s research interests include adult and pediatric tuberculosis, Drug resistant TB, TB treatment and novel regimens, TB epidemiology, TB diagnostics, novel biomarkers, HIV-associated TB, Non-tubercular mycobacteria and Mycobacterium avium-paratuberculosis. The research work includes multiple domains in Mycobacterium tuberculosis including understanding the epidemiology and pathogenesis of tuberculosis, molecular insights into spread of multidrug resistant tuberculosis, designing of novel rapid detection method for multidrug resistant tuberculosis, rifampicin resistance, molecular typing and whole genome sequencing. Her research has expanded knowledge of drug resistance mutations and molecular epidemiology of TB in India. Her pioneering work for detecting viable TB bacteria in treatment failure patients and subsequent work on therapeutic drug monitoring in this group of patients have direct policy relevance. She has ongoing research for newer drug regimens for Rifampicin sensitive and resistant TB. Her collaborative work on therapeutic use of the Indian vaccine against TB (MIP) paved the way for a Prevention of Disease vaccine trial. Her research on Biomarkers has yielded new molecules, which hold promise. Her work in the field of MDR contact tracing has yielded novel data and some novel hypothesis for relapse and reinfection TB and disease transmission. Her research has led to several patents, which are in different stages of translation to companies. One novel cost effective diagnostic tests for rapid detection of MDR and XDR TB has been validated by ICMR and will be taken up by a manufacturer shortly.

Her laboratory is NABL accredited, fully equipped to offer complete diagnostic services for diagnosis of tuberculosis (TB), Non-tubercular Mycobacteria (NTM), and drug resistance to various anti-tubercular drugs by molecular as well as conventional methods. The laboratory offers microscopy, culture (both liquid and solid), PCR and Gene-Xpert for diagnosis of TB and NTM. In addition, the conventional drug sensitivity testing in liquid and solid culture media, Gene-Xpert,Truenat, Line Probe Assay are available for detecting resistance to both first line and second line drugs. The laboratory is equipped with state of art molecular typing techniques for TB. All the techniques are quality assured.The laboratory carries out research under several funded schemes (Extramural funding support for Whole Genome Sequencing, Early Bactericidal Activity, Therapeutic Drug Monitoring, Point of Care tests (Aptamer based), Novel biomarkers, Rapid molecular drug resistance detection, Molecular Epidemiology of MDR-TB).

 

She is a Member, National TB Expert Group, National TB Elimination Program, GoI; Member, Subject Expert Committees, CDSCO (DCGI), GoI; Member, Diagnostic Committee, India TB Research Consortium, ICMR; Member, Operational Research Committee, National TB Elimination Program, GoI; Member, Project Review Committees of DBT, ICMR, TDB, GoI; Member, ICMR Task Force on Genital Tuberculosis; Member Editorial Board, Associate Editor, Frontiers in Medicine, Frontiers in Public Health and Frontiers in Microbiology; Scientific Collaborations with Several International and National Institutes; Reviewer for International and National Journals; More than 150 peer-reviewed Publications; Over 50 funded Research studi; Five patents

Publications:~150; Citations: 4017; H index: 29; I10 index: 60

 

 

Patents/Innovations:

S.no.

Title

Status

  1. 1.

An assay for identification of mycobacterial antigens in urine of pulmonary TB patients

Full patent granted

  1. 2.

Rapid detection of MDR-TB by reverse line blot assay

Full patent granted

  1. 3.

Development of oligonucleotides (probes)

For detection of XDR-TB

Full patent granted

  1. 4.

Rapid, safe, amplifiable DNA from Ziehl-Neelsen stained microscopic slides

Full patent awaited

  1. 5.

Indigenous gold standard kit for MDR and XDR-TB

Full patent awaited

 

 

 

 

 

 

 

Dr. Seema Sood

 

 

 

 

 

Dr. Seema Sood, MD, MNAMS

Professor, Department of Microbiology

E. mail: यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

Dr. Seema Sood has worked extensively towards introducing novel technologies for the diagnosis of sexually transmitted infections (STIs) which includes DNA Biosensor, Aptamers and others. She has 3 patents to her credit. She is currently working on POCT development for BV- a polymicrobial infection, evaluating alternate treatment options for gonorrhoea, STI testing in high-risk population like MSMs.

In the past, Dr. Sood has established a National Network for the surveillance of AMR for Neisseria gonorrhoeae with centres across India with financial assistance from ICMR. Her laboratory has been participating in the EQAS programme of WHO GASP since 2005 with excellent results.

She is the author of textbook of Microbiology for Nurses, published by Elsevier. Currently she is the Executive member of IUSTI World Committee( July 2021 onwards), Faculty National Board of Examination (NBE), formerly Assistant Editor, Indian Journal of Medical Microbiology, formerly member of editorial board of GASP newsletter (South-East Asian Region).

In addition to the STD laboratory, Dr. Sood has been working in the general Bacteriology Division where her areas of interest include enteric fever, ICU infections particularly, VAP.

Honors/ Awards:

  1. Member of the National Academy of Medical Sciences (NAMS)- India
    1. Included in Erudite Women’s Outstanding Contribution to the Indian Medical education: A recognition on International Women’s Day, 2021 
    2. ICMR Lala Ram Chand Kandhari Award for research in the field of Dermatology and Sexually Transmitted Diseases-2016
    3. Dr. P.S. Ranganathan Memorial Prize-Gold Medal-2013
    4. R.A. Bhujwala Award-2012

Patent: Three

Publications: 130 research papers, 3 chapters in book and 1 Text book

Text Book:  “Microbiology for Nurses” published by ELSEVIER (3rd edition-2013)

Few Research Papers

  1. Sood S, Agarwal SK, Singh R, Gupta S & Sharma VK. In vitro assessment of gentamycin and azithromycin based combination therapy against Neisseria gonorrhoeae isolates in India. J Med Microbiol, 2019: 68(4): 555-559.
  2. Anjana A, Sood S, Chaudhry R, Kapil A, Gupta S. A pilot study to determine NG, CT co-infection rates in symptomatic patients attending STI clinics in New Delhi, India. Ind J Dematol Venereol Leprol, 2022: 88(3):367-371.
  3. Mahajan N, Sood S, Das BK, Kapil A, Kar HK, & Sharma VK. Molecular Characterization of decreased susceptibility (DS) to ceftriaxone and genotyping of Neisseria gonorrhoeae isolates in New Delhi, India. DMID 2021; 101(1): 115423.
  4. Dev T, Mahajan N, Sood S, Gupta S. The ping-pong infection in gonorrhoea: Lest we forget. Ind J Dermatol Venereol Leprol, 2021; 88(1): 109-11.
  5. Challa A, Sood S,  Kachhawa G, Upadhyay A, Dwivedi S & Gupta S. Diagnostic discordance between Amsel’s criteria and Nugent scoring method in the assessment of Bacterial Vaginosis. Sex Health. 2022: 18(6):512-514.

 

 

 

 

 

 

 

 

Prof. Rama Chaudhry

Prof. Rama Chaudhry

Dean (Research)

Head, Department of Microbiology,

All India Institute of Medical Sciences, New Delhi

Email : यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

 

Prof. Chaudhry has done her MBBS from LHMC and MD from AIIMS, New Delhi. Presently she is working as a Dean (Research), Professor and Head in the Department of Microbiology at All India Institute of Medical Sciences (AIIMS), New Delhi. She has an experience of over 35 years in the field of academics and medical-research to her credit. She has received many honors and memberships from various national and international scientific organizations. She has been among the research advisory and project review committees of national funding agency such as the DBT, CSIR and ICMR. Her research and international collaborations, has resulted in over 205 scientific publications in various journals of international repute including Nature, BMJ, EID, JCM, Lancet, TMID, JCV etc.  She has contributed several book chapters and edited books. 

 

Major Research Thrust Areas:

 

  • Anaerobic Bacteriology -Molecular characterization and diagnostics for anaerobic-pathogens including C. botulinum and C. difficile.
  • Special Bacterial Pathogens–Diagnosis and characterization of special pathogens including Mycoplasma, Legionella, Rickettsia, Leptospira, Bartonella and Lyme disease
  • Human Microbiome – Metagenomic characterization and profiling of human microbiota to assess the microbial and metabolic markers for different diseases and host microbe interactions including gut colonization and immunomodulation.
  • Probiotics– Application of probiotics for human health and development of indigenous probiotics
  • Antimicrobial Resistance: Antibiotic susceptibility of clinical and environmental isolates including anaerobic bacterial pathogens
  • Bacteriophages: Isolation and characterization of bacteriophages against drug resistant bacteria

 

Key Research Contributions:

 

Prof Chaudhry is in-charge of the Anaerobic-bacteriology, Special Bacterial Pathogen Laboratory and Metagenomics Laboratory at AIIMS that caters to the diagnostics needs as a nodal center for many teaching and non-teaching hospitals in the country.  

Areas of her research include- Anaerobic bacteriology, Infectious Diseases, Drug resistant enteric infections in India, Human microbiome, Metagenomics bacteriophage and Probiotics. Her research is also focussed on emerging and re-emerging vector borne diseases (Rickettsial diseases, Lyme, Ehrlichia and Anaplasma) and potential use of bacteriophage as biocontrol agent against MDR pathogens contaminated surfaces. During the COVID pandemic, she has also worked to explore the role of atypical bacterial pathogens in the causing superadded infections in COVID patients and their role in the mortality and morbidity of the COVID patients. 

Prof. Chaudhry conducted many conferences, workshops and CMEs in the field of anaerobic bacteriology, mycoplasma, probiotics and COVID-19. As the ASM International Ambassador to India she created awareness among microbiologists and clinicians and trained manpower for these specialized diagnostics even in small laboratory settings.

 

  1. Anaerobic bacteriology: Dr. Chaudhry is in-charge of anaerobic-lab in the department of Microbiology, which serves as a referral lab for several teaching and non-teaching hospitals in the country. This lab is responsible for its diagnostics catering via its routine culture and drug susceptibility testings, supply / identification of anaerobic strains on demand, and also provides hands on training programs for summer-trainees. The active research in this area involves studies pertaining molecular characterisation and diagnostics for anaerobic-pathogens w.r.t. C. botulinum and C. difficile. An outbreak of suspected C. butyricum botulism in India was investigated (Emerg. Infect. Dis., 1998; 4(3): 506-7) by applying these recent techniques. In a preliminary study of C. difficile infection at AIIMS, a tertiary care hospital, the prevalence of infection has been found to be 15%.
  • Enteric pathogens: Prof. Chaudhry’s research on human salmonellosis is a significant contribution. Early research work revealed the emergence of Salmonella Paratyphi-A strains with unusual resistance to quinolones causing enteric fever treatment failures in New Delhi.  An outbreak by resistant S. Paratyphi-A was also investigated in this region. Some of her research work on Salmonella, published in CDC and ASM journals have been cited in renowned medical textbooks- Topley& Wilson’s Molecular Medical Microbiology, Konemans’ Diagnostics Microbiology and Mandell etc.

 

  1. 2.         Special Bacterial Pathogens
  • Mycoplasma pneumoniae: In an ICMR-funded project, comparative evaluation of available diagnostic tests for M. pneumoniae were carried out. Since most of the kits are too expensive and usually imported, an effort was made to develop our own indigenous tests by standardizing ELISA using self-prepared antigens (a 170 kD-virulence protein-P1) while comparing it with other techniques. The laboratory is equipped for M. pneumoniae diagnosis by culture, antigen detection and PCR. She has contributed significant work on epidemiology and expression studies of immunodominant epitopes of P1, P30, P116 gene of Mycoplasma pneumoniae to develop an in-house rapid point of care test.
  • Legionella pneumophila: She has reported the role of Legionella in the atypical pneumonia and isolated it from the environment for the first time from India. The environmental isolates showed high percentage of the pathogenicity loci which indicate disease-causing Legionella in hospital environment. As a countermeasure, point of use filters was installed to the drinking water taps.  Antibiotic susceptibility testing, virulence gene detection, and genotyping were carried out in environmental Legionella.  The genetic analysis of environmental Legionella isolates showed diversity. 
  • Lyme disease, Rickettsia and Bartonella: Prof. Chaudhry is working on Lyme disease research to advance the scientific knowledge and laboratory diagnosis of this emerging tick-borne infection in India.  This is the only laboratory equipped with Standard Two-tiered testing serology and various molecular techniques to diagnose Lyme disease and other co-infections in India which will help to treat this infection in its early stages. Prof. Chaudhry is conducting a Multicenter extramural research grant supported from ICMR to investigate the clinical and epidemiological features of Lyme disease in India.
  • Antimicrobial Resistance: Antibiotic susceptibility of clinical and environmental isolates including anaerobic bacterial pathogens

 

  1. Metagenmics:
  • Probiotics and Microbiome: As a pioneer in the field of probiotics from India, she collaborated with researchers from University of Maryland and contributed in NIH, USA sponsored studies published in ‘Nature 2017’. Prof. Chaudhry also conducted a study on gut microbiota in healthy Indian subjects, patient of IBD and colon cancer.
  1. Bacteriophages: Bacteriophages are considered as natural predators of bacteria. Prof. Chaudhry is working on Isolation and characterization of bacteriophages against drug resistant bacteria including A. baumannii, P. aeruginosa, K. pneumoniae, E coli and S. aureus from the river Ganga and other environmental samples.

 

 

Honors and Awards

 

  1. ASM International Ambassador to India by American Society for Microbiology, USA, 2016-2021.
  2. Prestigious ‘Atal Swasthya Bhushan Samman 2019’ by Honorable Lok Sabha Speaker, Parliament of India.
  3. IAMM Endowment Lecture Award 2014 by Indian Association of Medical Microbiologist (IAMM).
    1. Dr R Sengupta and Dr A.M. Saoji Memorial Prize Gold Medal- 2009 for best paper in Immunology in XXXIII National Conference of Indian Association of Medical Microbiologists held in JSS Medical College, Mysore.
    2. Dr. S.S. Kelkar Memorial Gold Medal Award twice in 2017 & 2002 by Indian association of medical microbiologist for an outstanding scientific work accomplished entitled “Expression and immunological characterization of the carboxy-terminal region of the P1 adhesin protein of Mycoplasma pneumoniae.” (2002)

 

Best publications

 

  1. Vinayaraj EV, Gupta N, Sreenath K, Thakur CK, Gulati S, Anand V, Tripathi M, Bhatia R, Vibha D, Dash D, Soneja M, Kumar U, Padma MV, Chaudhry R. Clinical and laboratory evidence of Lyme disease in North India, 2016-2019.Travel Med Infect Dis. 2021 Jun 30;43:102134. doi: 10.1016/j.tmaid.2021.102134.IF 6.2
  1. Sreenath K, Batra P, Vinayaraj EV, Bhatia R, SaiKiran K, Singh V, Singh S, Verma N, Singh UB, Mohan A, Bhatnagar S, Trikha A, Guleria R, Chaudhry R. Coinfections with Other Respiratory Pathogens among Patients with COVID-19.MicrobiolSpectr. 2021 Jul 21: e0016321. doi: 10.1128/Spectrum.00163-21.IF 6.62
  1. Chaudhry R, Sreenath K, Arvind V, Vinayaraj EV, Tanu S. Legionella pneumophila Serogroup 1 in the Water Facilities of a Tertiary Healthcare Center, India. Emerg Infect Dis. 2017 Nov; 23(11):1924-1925. IF 6.9
  2. Pinaki Panigrahi, Sailajanandan Parida, Nimai C. Nanda, RadhanathSatpathy, Lingaraj Pradhan, Dinesh S. Chandel, Lorena Baccaglini, Arjit Mohapatra, Subhranshu S. Mohapatra, Pravas R. Misra, Rama Chaudhry, Hegang H. Chen, Judith A. Johnson, J. Glenn Morris Jr, Nigel Paneth & Ira H. Gewolb (2017): A randomized synbiotic trial to prevent sepsis among infants in rural India: Nature 548, 407–412.IF 40.1
  3. Chaudhry R, Lall SB, Mishra B, Dhawan B. A foodborne outbreak of organophosphate poisoning. British Medical Journal.1998 Jul 25; 317(7153):268-9. IF19.9
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