Research Projects Ongoing In Department
Trials running as Principal Investigators
1) Patil PA. Cervical cancer tumor micro-environment immune-profiling and effect on early response to standard chemoradiotherapy in Indian patients. Ethics committee AIIMS IEC-878/04.09.2020, RP-65/20. Sample size= 54
2) Sharma A. “The SWOAR Trial: A Phase III trial evaluating sparing of swallowing and aspiration related organs at risk & submandibular gland with Intensity-modulated radiotherapy versus standard IMRT in Head and neck squamous cell carcinomas” (CTRI REF/2021/05/043810) Sample Size=136
3) Sharma A. “The Eliminate Trial: A Phase II/III randomized trial evaluating omission of radiotherapy to regional lymphatic’s in pN0/N1 neck for Oral Cavity carcinomas”(CTRI REF/2021/06/044351) Multicentric trial 12 centers participating across India, Sample Size =496.
4) Mallick S. Optimum radiation dose for palliation in head and neck Squamous cell carcinoma – A phase 3 randomized controlled trial (Oprah) Sample Size=286
5) Mallick S. Phase II study of hypo-fractionated accelerated radiotherapy with concurrent and maintenance temozolomide in newly diagnosed IDHwt Anaplastic Astrocytoma (NCI-R-01-HyRAA). Sample Size=60
6) Mallick S. One week or three-week Adjuvant Radiation in breast cancer: A phase III non-inferiority trial (NCI-R-02- OthAR). Sample Size=680
7) Mallick S. Standardizing sequence of Adjuvant Radiation and Systemic therapy for breast cancer (STARS): A phase III randomized controlled trial. Sample Size=700
8) Ghosh et al. HYPCON Trial: Hypofractionated adjuvant radiation therapy in head and neck malignancies: a randomized phase II study. Sample Size 44
9) Dagar et al A phase II study of curative approach treatment along with SABR compared to standard of care for bone-only oligometastatic disease in breast cancer patients. Sample size 40.
Land Mark Contribution
Research:
Extramural Grants:
PI: Dr Hari Sagiraju.
PI: Dr Jitendra Kr Meena
PI: Dr Hari Sagiraju.
Intramural Grants:
PI: Dr Jitendra Kr Meena.
PI: Dr Hari Sagiraju
PI: Dr Hari Sagiraju
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