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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi
कॉल सेंटर:  011-26589142

Research

Research

The department is actively engaged in extramural and intramural research projects over the past many years. The department has been recognized as a Unit of Excellence for Cancer Research in Multiple Myeloma by Department of Biotechnology.

 

Extramural Research Projects

  1. Molecular analysis of cytogenetically normal acute myeloid leukemia; Dr. Rajive Kumar
  2. Unit of Excellence on Cancer Research on Multiple Myeloma; Dr. Ritu Gupta
  3. Minimal Residual Disease Estimation in Multiple Myeloma using Image Processing: Design and Development of Myelomaimager- an Automated Computer Assisted Tool; Dr. Ritu Gupta
  4. Resistance to tyrosine kinase inhibitors in Indian patients with chronic myeloid leukemia-a mechanistic view; Dr. Ritu Gupta
  5. Design and Development of Leukoanalyzer, an Automated Computer Assisted Tool, for Minimal Residual Disease Estimation (MRD) in B-Lineage Acute Lymphoblastic Leukemia (ALL) using Image Processing Techniques; Dr. Ritu Gupta
  6. Elucidation of pathologically relevant miRNAs responsible for disease progression and resistance to chemotherapy in CLL; Dr. Ritu Gupta
  7. Interrogating the myeloma genome with reference to microRNAs modulated gene expression; Dr. Ritu Gupta
  8. Prognostic Relevance of DNA methylation in chronic lymphocytic leukemia; Dr. Ritu Gupta
  9. Th17 cells in pathobiology of multiple myeloma; Dr. Ritu Gupta; Natural Killer & T-lymphocyte Subset Analysis in Multiple Myeloma; Dr. Ritu Gupta
  10. Molecular & immunological basis of biological heterogeneity in CLL; Dr. Ritu Gupta; HIF-1α as regulator of angiogenesis in multiple myeloma; Dr. Ritu Gupta
  11. Regulatory T-Cell repertoire in plasma cell myeloma; Dr. Ritu Gupta
  12. Immunophenotypic characterization of plasma cells by flow cytometry in health & disease with particular reference to plasma cell myeloma; Dr. Ritu Gupta
  13. Early immature T- lymphoblastic leukemia (ALL): evaluation of early thymic precursor T-ALL immunophenotype, absence of biallelic deletion of TCR γ chains (ABD) and expression of MEF2C as predictors of treatment response as assessed by minimal residual disease determination; Dr. Anita Chopra
  14. Evaluation of  expression of  FGFR1, FGFR2 , Cyclin D1 & PIK3CA  and PIK3CA  mutations  in of Hormone Receptor(Estrogen & Progesterone ) positive and HER2 receptor negative cases of primary breast cancer; Dr. Pranay Tanwar
  15. A prospective study to evaluate WT1 gene expression as predictive molecular marker of disease progression in de novo cases of Acute myeloid Leukemia; Dr. Pranay Tanwar
  16. Comparative study of Genetic, Clinical and Epidemiological factors of Breast Cancer in Indian population; Dr. Pranay Tanwar
  17. Evaluation of HE4 level in epithelial ovarian cancer for diagnosis & monitoring of therapy; Dr. Amar Ranjan Singh
  18. Role of NFKB1 gene function in hematological diseases; Dr. Gurvinder Kaur

 

 

Intramural Research Projects

  1. Development of laboratory algorithm for molecular classification of Multiple Myeloma in clinical practice; Dr. Ritu Gupta
  2. Towards a comprehensive molecular score in CLL; Dr. Ritu Gupta
  3. Assessment of multi-drug resistance pattern in acute myeloid leukemia and response to therapy; Dr. Ritu Gupta
  4. Prevalence of intrachromosomal amplification of chromosome 21 (iAMP21) in B-ALL; Dr. Sanjeev Kumar Gupta
  5. IKZF1 (Ikaros) mutations in B cell acute lymphoblastic leukemia; Dr. Sanjeev Kumar Gupta
  6. Detection of minimal residual disease in T-lineage acute lymphoblastic leukemia by a low-cost PCR analysis of clonal T-cell receptor gene rearrangement; Dr. Anita Chopra
  7. Molecular determinants of prednisolone sensitivity in pediatric acute lymphoblatic leukemia; Dr. Anita Chopra
  8. A prospective study to evaluate Wilm’s tumor 1 (WT1) mutation in de novo cases of Acute myeloid Leukemia and correlating their outcome  with treatment response; Dr. Pranay Tanwar
  9. Evaluation of Thrombopoietin as a marker of sepsis in post operative cases of gastrointestinal malignancy; Dr. Amar Ranjan Singh
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