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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Hospital Statistics 2015-16

Contacts

Contact : Room No. 239, II Floor, Dr. B.R.A.IRCH, AIIMS, New Delhi, India
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone No.: 91-11-26594439 (O); 91-11-29575050; 91-11-29575048 (Lab)

Vacancies

Lab Oncology
Vacancies

JRF position:
Please check AIIMS website for open Ph.D.and other research positions.

Post-Doc position
Candidates who have submitted/awarded Ph.D. recently can contact to me with your CV with your specific experimental skills, instrument handling experience, and one-page write-up about your thesis work. (CV can be sent to me directly at Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Summer/project trainee (no vacancy)

Publications

2019

  • Thakral, Deepshi, et al. "Rapid Identification of Key Copy Number Alterations in B-and T-cell Acute Lymphoblastic Leukaemia by Digital Multiplex Ligation-Dependent Probe Amplification." Frontiers in Oncology 9 (2019): 871
  • Kumar L, Ramavath D, Kataria B, Tiwari A, Raj A, Chellapuram SK, Mookerjee A, Sahoo RK, Malik PS, Sharma A, Gupta R, Sharma OD, Biswas A, Kumar R, Thulkar S, for AIIMS Myeloma Group. High-dose chemotherapy followed by autologous stem cell transplant for multiple myeloma: Predictors of long-term outcome. Ind J Med Res 2019;14996):730-739.
  • Mann M, Kumar S, Chauhan SS, Bhatla N, Kumar S, Bakhshi S, Gupta R, Sharma A, Kumar L.PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix. Oncotarget 2019;10(42):4262-4275. doi: 10.18632/oncotarget.27008. (PMID: 31303961)
  • Vanidassane I, Gogia A, Raina V, Gupta R. Treatment Related Acute Myeloid Leukemia in Breast Cancer Survivors: A Single Institutional Experience. Indian J Hematol Blood Transfus 2019 Jul;35(3):561-562. doi: 10.1007/s12288-019-01078-w. (PMID: 31388274)
  • Gogia A, Gupta R, Kumar L, Sharma A, Soni L. Chronic lymphocytic leukemia with deletion 17p: An Indian scenario. South Asian J Cancer. 2019; 8(1):40. (PMID: 30766851)
  • Kaur G, Gupta R*, Mathur N, Rani L, Kumar L, Sharma A, Singh V, Gupta A, Sharma OD. Clinical impact of chromothriptic complex chromosomal rearrangements in newly diagnosed multiple myeloma. Leuk Res. 2019; 76:58-64. (PMID: 30576858)
  • Rani L, Gogia A, Singh V, Kumar L, Sharma A, Kaur G, Gupta R*. Comparative assessment of prognostic models in Chronic Lymphocytic Leukemia: Evaluation in Indian Cohort. Ann Hematol. 2019; 98:437-443. (PMID: 30338367)
  • Mittal A, Gogia A, Mallick S, Gupta R. Leukemia Cutis: A Rare Initial Presentation of Chronic Lymphocytic Leukemia. Indian J Hematol Blood Transfus 2019;35(2):367-368. (PMID: 30988580)

2018

  • Gupta A, Mallick P, Sharma O, Gupta R, Duggal R. PCSeg: Color model driven probabilistic multiphase level set based tool for plasma cell segmentation in multiple myeloma. PLoS One 2018; 13(12):e0207908 (PMID: 30540767)
  • Kashyap R, Awasthi NP, Gupta R. Clinical and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in Indian patients. J Appl Hematol 2018; 9:85-90
  • Gupta R*, Kaur G, Kumar L, Rani L, Mathur N, Sharma A, Dahiya M, Shekhar V, Khan S, Mookerjee A, Sharma OD. Nucleic acid based risk assessment and staging for clinical practice in multiple myeloma. Ann Hematol. 2018; 97(12):2447-2454. (PMID: 30056581)
  • Gupta R*, Dahiya M, Kumar L, Shekhar V, Sharma A, Ramakrishnan L, Sharma OD, Begum A. Prevalence of Monoclonal Gammopathy of Undetermined Significance in India- A Hospital Based Study. Clin Lymphoma Myeloma Leuk. 2018;18:e345-e350. (PMID: 29980412)
  • Patekar M, Gogia A, Tiwari A, Kumar L, Sharma A, Mallick SR, Sharma MC Thulkar S, Gupta R. Adult Burkitt lymphoma: An institutional experience with a uniform chemotherapy protocol. South Asian J Cancer. 2018;7(3):195-199. (PMID: 30112340)
  • Rai S, Bhardwaj U, Misra A, Singh S, Gupta R. Comparison between photostability of Alexa Fluor 448 and Alexa Fluor 647 with conventional dyes FITC and APC by flow cytometry. Int J Lab Hematol. 2018;40(3):e52-e54. (PMID: 29575796)
     

2017

  • Kumar L, Gogi L, Patel A, Mookerjee A, Sahoo R, Malik P, Sharma A, Thulkar S, Kumar R, Biswas A, Gupta R, Sharma O. Multiple myeloma with Extra medullary disease: Impact of Autologous stem cell transplantation on outcome. Bone Marrow Transplantation 2017; 52:1473-1475 (PMID: 28805789)
  • Rani L, Mathur N, Gupta R*, Gogia A, Kaur G, Dhanjal JK, Sundar D, Kumar L, Sharma A. Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia. Clin Epigenetics. 2017;9:57. doi: 10.1186/s13148-017-0356-0. (PMID:28572861)
  • Gupta R*, Kumar L, Dahiya M, Mathur N, Harry P, Sharma A,Sharma OD, Shekhar V. Minimal Residual Disease Evaluation in ASCT recipients with Multiple Myeloma. Leuk Lymphoma2017;58(5):1234-1237(PMID: 27658735)
  • Sharma A, Tilak T, Bakhshi S, Raina V, Kumar L, Chaudhary SP, Sahoo RK, Gupta R, Thulkar S. Lactobacillus brevis CD2 lozenges prevent oral mucositis in patients undergoing high dose chemotherapy followed by haematopoietic stem cell transplantation. ESMO Open. 2017;1(6):e000138. (PMID:28848667)
  • Yanamandra U, Khattry N, Kumar S, Raje N, Jain A, Jagannath S, Menon H, Kumar L, Varma N, Varma S, Saikia T, Malhotra P; for IMAGe Group. Consensus in the Management of Multiple Myeloma in India at Myeloma State of the Art 2016 Conference. Indian J Hematol Blood Transfus. 2017;33(1):15-21.PMID:28194051
     

2016

  • Gupta R*.Genomic Classification of Acute Myeloid Leukemia- An Incessantly Evolving Concept. Natl Med J India 2016;29(5):283-285 (PMID:28098084)
  • Kumar L, Boya RR, Pai R, Harish P, Mookerjee A, Sainath B, Patekar MB, Sahoo RK, Malik PS, Sharma OD, Gupta R. Autologous stem cell transplantation for multiple myeloma: Long-term results. Natl Med J India. 2016;29(4):192-199. (PMID: 28050994)
  • Sharawat SK, Raina V, Kumar L, Sharma A, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia: A prospective pilot study from India. Indian J Med Res. 2016;143(Supplement):S11-S16. (PMID: 27748272)
  • Baghmar S, Kumar L, Rani L, Mathur N, Sreenivas V, Malik PS, Tilak TVSVGK, Gupta R*. Prognostic Relevance of T Regulatory Cells in Patients with advanced-Stage Serous Carcinoma Ovary. Indian J Gynecol Oncolog 2016; 14:20.
  • Gupta R*, Chandgothia M, Dahiya M, Bakhshi S, Sharma A, Kumar L. Multi-Drug Resistance Protein 1 as Prognostic Biomarker in Clinical Practice for Acute Myeloid Leukemia. Int J Lab Hematol 2016; 38(5):e93-97 (PMID: 27321806)
  • Rani L, Mathur N, Gogia A, Vishnubhatla S, Kumar L, Sharma A, Dubey D, Kaur P, Gupta R*. Immunoglobulin Heavy Chain Variable Region Gene Repertoire and B-Cell Receptor Stereotypes in Indian Patients with Chronic Lymphocytic Leukemia. Leuk Lymphoma 2016;57(10):2389-400(PMID:26942309)
  • Nataraj V, Mathur N, Rani L, Gupta R, Bakhshi S. Serial assessment of circulating T regulatory cells and T helper 17 cells in pediatric non-Hodgkin lymphoma: a prospective study. Leuk Lymphoma 2016;57(7):1739-42 (PMID:26690272)
  • Nataraj V, Tiwari A, Mathur N, Rani L, Gupta R, Mallick S, Sharma MC, Bakhshi S. Vascular endothelial growth factor expression in pediatric non-Hodgkin lymphoma: A prospective study. PediatrHematolOncol. 2016;33(3):168-70 (PMID:27184774)
  • Chharchhodawala T, Gajendra S, Tiwari P, Gogia A, Gupta R*. Therapy related acute myeloid leukemia with t(8;16) mimicking acute promyelocytic leukemia. Indian J Hematol Blood Transfus 2016; 32:20-22 (PMID:27408347)
  • Sharma S, Arif M, Nirala RK, Gupta R, Thakur SC. Cumulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress. J Sci Food Agric. 2016;96(5):1500-1510. (PMID: 25966322)
     

2015

  • Shah B, Gajendra S, Gupta R*, Sharma A. Novel Cytogenetic aberrations in a patient of chronic myeloid leukemia with blast crisis. J Clin Diagn Res 2015; 9(5):XD05-XD06 (PMID:26155548)
  • Das A, Singh A, Gajendra S, Gupta R*, Sazawal S, Seth R. An unusual case of phenotype switch between AML FAB subtypes. Clin Case Rep. 2015;3(2):118-20. (PMID: 25767711)
  • Bahl A, Sharma A, Raina V, Kumar L, Bakhshi S, Gupta R, Kumar R. Long-term outcomes for patients with acute myeloid leukemia: A single-center experience from AIIMS, India.Asia Pac J ClinOncol. 2015; 11: 242-252 (PMID:25639656)
     

2014

  • Sharma S, Gupta R, Thakur SC. Attenuation of Collagen Induced Arthritis by Centellaasiatica Methanol Fraction via Modulation of Cytokines and Oxidative Stress. Biomed Environ Sci. 2014; 27(12): 926-938 (PMID: 25484009)
  • Gajendra S, Gogia, A, Das P, Gupta R, Tanwar P. Acute myeloid leukemia presenting as “Bowel Upset”- A case report. J ClinDiag Res. 2014; 8(7): FD09-10 (PMID: 25177572)
  • Kumar L, Iqbal N, Mookerjee A, Verma RK, Sharma OD, Batra A, Pramanik R, Gupta R. Complete response after autologous stem cell transplant in multiple myeloma. Cancer Med. 2014; 3:939-46. (PMID: 24777883)
  • Tilak T, Sherawat S, Agarwala S, Gupta R, Vishnubhatla S, Bakhshi S. Circulating T-Regulatory Cells in Neuroblastoma: A Pilot Prospective Study. PediatrHematolOncol. 2014; 31(8):717-22. (PMID:24684178)
  • Gogia A, Raina V, Gupta R, Gajendra S, Kumar L, Sharma A, Kumar R, Vishnubhatla, S. Prognostic and predictive significance of Smudge cell percentage on routine blood smear in chronic lymphocytic leukemia.Clin Lymphoma Myeloma Leuk. 2014; 14(6):514-7 (PMID: 24656596)
  • Sharawat SK, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. FLT3-ITD Mutation in Relation to FLT3 Expression in Pediatric AML: a Prospective Study from India. PediatrHematolOncol. 2014; 31(8):717-22 (PMID: 24498869)
  • Sharawat SK, Gupta R, Raina V,Kumar L, Sharma A, Iqbal S,Bakhshi R, Vishnubhatla S, Bakhshi S. Quantitative Assessment of BAX Transcript and Flow-cytometric Expression in Acute Myeloid Leukemia: a prospective study FLT3-ITD. Hematology 2014;19(7):404-11 (PMID: 24620954)
  • TilakTV,Sharawat SK, Gupta R, Agarwala S, Khan SA, Rastogi S, Sreenivas V, BakhshiS.Circulating T- regulatory cells in PNET: A prospective study. Pediatr Blood Cancer 2014;61:228-232 (PMID: 23997029)
  • Gajendra S, Gogia A, Tanwar P, Sahoo MK, Bhethanabhotla S, Durgapal P, Gupta R*. Synchronous metastatic pulmonary adenocarcinoma with small cell lymphoma. Leuk Lymphoma 2014; 55: 1678-1680. (PMID: 24073807)
  • Gogia A, Mehta P, Pramanik R, Gupta R. Chronic lymphocytic leukemia with massive ascites: An unusual presenting manifestation. South Asian J Cancer. 2014;3(4):235-6 (PMID: 25422818)
  • Gajendra S, Gupta R*,Chandgothia M, Kumar L, Gupta R, Chavan SM. Chronic Neutrophilic Leukemia with V617F JAK2 Mutation. Indian J Hematol Blood Transfus2014;30(2):139-42 (PMID: 24839370)
     

2013

  • Gajendra S, Gupta R, Gupta R*, Kumar L. Coexistence of scleroderma with multiple myeloma: a rare association. BMJ Case Rep. 2013; Sep 10; 2013. doi:pii: bcr2013200639. 10.1136/bcr-2013-200639 (PMID: 24022902)
  • Ghosh J, Singh RKB, Saxena R, Gupta R, Vivekanandan S, Sreenivas V, Raina V, Sharma A, Kumar L. Prevalence and aetiology of anaemia in lymphoid malignancies. Natl Med J India 2013; 26: 79-81 (PMID:24093980)
  • Sharawat SK, Gupta R, Raina V,Kumar L, Sharma A, Iqbal S,Bakhshi R, Vishnubhatla S, Bakhshi S. Increased co-expression of c-KIT and FLT-3 receptors on myeloblasts: independent predictor of poor outcome in pediatric acute myeloid leukemia.Clinical Cytometry2013; 84(6): 390-397 (PMID: 23740774)
  • Gogia A, Gupta R, Raina V. Disseminated tuberculosis mimicking relapse in Hairy cell leukemia. Indian J Cancer 2013;50:321
    47. Gogia A, Raina V, Gupta R. Massive ascites as apresenting feature of Plasma Cell Leukemia. Indian J Cancer 2013;50:301
  • Gogia A, Sharma A, Raina V, Kumar L, Gupta R, Kumar R. Prevalence of ZAP70 and CD38 in Indian chronic lymphocytic leukemia patients. Indian J Cancer 2013;50(4):333-336
  • Sharawat SK, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. BAX/BCL2 RMFI ratio predicts better induction response in pediatric patients with acute myeloid leukemia. Pediatr Blood Cancer. 2013; 60:E63-6 (PMID: 23553948)
  • Bhaskar A, Gupta R*, Sreenivas V, Rani L, Kumar L, Sharma A, Sharma OD, Sharma MC, Thakur SC. Synergistic effect of vascular endothelial growth factor and angiopoietin-2 on progression free survival in multiple myeloma. Leuk Res. 2013; 37:410-415 (PMID: 23332455)
  • Baghmar S, Mohanti BK, Sharma A, Kumar L, Prakash G, Kumar S, Gupta R, Kumar R, Raina V. Solitary Plasmacytoma: 10 years’ experience at AIIMS, New Delhi. Leuk Lymphoma. 2013; 54:1665-1670. (PMID: 23163525)
  • Bhaskar A, Gupta R*, Sreenivas V, Kumar L, Sharma A, Sharma MC, Prasenjit Das P, Thakur SC. Angiopoietins as biomarker of disease activity and response to therapy in multiple myeloma. Leuk Lymphoma. 2013; 54:1473-8 (PMID: 23113684)
     

2012-2003

  • Sharma A, Bahl A, Raina V, Kumar L, Gupta R. Dasatinib in chronic myeloid leukemia: A limited Indian experience. Asia-Pacific Journal of Clinical Oncology. 2012; 8:375-9 (PMID: 22897916)
  • Gogia A, Sharma A, Raina V, Kumar L, Vishnubhatla S, Gupta R, Kumar R. Assessment of 285 cases of CLL seen at single large tertiary centre from Northern India. Leuk Lymphoma. 2012; 53:1961-5 (PMID: 22475243)
  • Gogia A, Sharma A, Raina V, Gupta R. Priapism as an initial presentation of chronic lymphocytic leukemia. Leuk Lymphoma. 2012;53:1638-9 (PMID:22242818)
  • Bhaskar A, Gupta R*, Kumar L, Sharma A, Sharma MC, Kalaivani M, Thakur SC. Circulating endothelial progenitor cells as potential prognostic biomarker in multiple myeloma. Leuk Lymphoma. 2012; 53:635-40. (PMID: 21973309)
  • Naseem S, Kaur S, Gupta R*, Kashyap R, Nityanand S. Plasma Cell Leukemia: Case Series From a Tertiary Center with Review of Literature. Ind J Hematol Blood Transfus2012; 28:10-14 (PMID:23449039)
  • Ganeshan P, Gupta R*, Hakim M, Kumar L, Bhaskar A, Sharma A. Reconstitution of regulatory T-cells after autologous transplantation in multiple myeloma. Int J Hematol. 2011 ;94:578-9 (PMID:22045305)
  • Agrawal V, Gupta A, Gupta R*, Sharma MC, Das P. Nonleukemic granulocytic sarcoma of kidney with mixed phenotype blasts: A diagnostic dilemma. Indian J PatholMicrobiol. 2011; 54:606-8 (PMID: 21934235)
  • Smeeta G, Gupta R*, Sharma A, Gupta R, Gogia A. Acute myeloid leukemia with Pseudo-Chediak Higashi granules and intracytoplasmic vacuoles. Eur J Haematol. 2011 Jun 16. doi: 10.1111/j.1600-0609.2011.01668.x. (PMID: 21679254)
  • Gupta R*, Ganeshan P, Hakim M, Verma R, Sharma A, Kumar L. Significantly reduced regulatory T cell population in patients with untreated multiple myeloma. Leukemia Research 2011;35: 874-878 (PMID: 21146215)
  • Puri K, Singh P, Das RR, Seth R, Gupta R. Diagnostic dilemma of JMML coexisting with CMV infection. Indian J Pediatr. 2011; 78: 485-487 (PMID: 21193971)
  • Ghosh I, Bakhshi S, Gupta R*. Acute Basophilic Leukemia in an Infant with Proptosis. Indian J Pathol Microbiol 2011; 54: 210-211 (PMID: 21393925)
  • Agarwal R, Sreenivas V, Gupta R, Bakhshi S. Diagnostic and Follow up Eosinophilia is not Predictive of Outcome in Childhood Acute Myeloid Leukemia. J Pediatr Hematol Oncol 2011;33:e51-53 (PMID: 21285899)
  • Panda D, Gupta N, Gupta R, Bakhshi S. Pediatric myelodysplastic syndrome with cytoplasmic vacuolation in myeloid precursors. J Pediatric Hematol Oncol 2011; 33:59-61 (PMID: 21178710)
  • Agarwal P, Sekhar Das S, Gupta R, Khetan D, Chaudhary R. Quantification of Feto-Maternal Hemorrhage: Selection of Techniques for a Resource-Poor Setting. Gynecol Obstet Invest. 2010;71:47-52 (PMID: 21160194)
  • Medhi K, Raina V, Kumar L, Sharma A, Bakhshi S, Gupta R, Kumar R. Response Assessment of chronic myeloid leukemia (CML) patients receiving imatinibmesylate (Glivec) therapy: Experience from a single center in developing country. Leuk Lymphoma 2010; 51:1850-1854 (PMID: 20849386)
  • Gupta N, Kumar S.S, Gupta R*, Bakhshi S. Childhood chronic myeloid leukemia with monocytosis. Indian J Pediatr 2010; 77: 1143 (PMID: 20882436).
  • Prabhu SB, Gupta R*, Seth R. Juvenile myelomonocytic leukemia presenting with co-existent cytomegalovirus infection – A case report. J Pediatric Hematol Oncol 2010;32(4):e153-4 (PMID: 20445410)
  • Singhal M, Raina V, Gupta R, Das P. T cell-prolymphocytic leukemia detected in a patient of breast cancer at the time of recurrence: a case report. Cases Journal 2010;3:4 (PMID: 20076807)
  • Agarwal R, Gupta R*,Bakhshi S, Sharma A. Unusual cytochemical reactivity in granular acute lymphoblastic leukemia: A rare Case report. Turk J Hematol 2010;27:43-45 (PMID: 27265798)
  • Gupta R*, Bhaskar A, Kumar L, Sharma A, Jain P. Flow cytometric immunophenotyping and minimal residual disease analysis in multiple myeloma. Am J Clin Pathol 2009;132:728-732 (PMID: 19846814)
  • Ganesan P, Thulkar S, Gupta R, Bakhshi S. Childhood Aleukemic Leukemia with Hypercalcemia and Bone Lesions Mimicking Metabolic Bone Disease: Case Report and Review of Literature. J Pediatric Endocrinology and Metabolism 2009;22:463-467 (PMID: 19618667)
  • Bhaskar A, Gupta R*, Sharma A, Kumar L, Jain P. Analysis of bone marrow plasma cells in patients with solitary bone plasmacytoma. Cancer Therapy 2009;7:49-52 (PMID: 26834513)
  • Gupta N, Gupta R*, Bakhshi S. Transient myeloproliferation mimicking JMML associated with parvovirus infection of infancy. Pediatr Blood Cancer 2009; 52: 411-413 (PMID: 18989883)
  • Srivastava S, Naseem S, Gupta R*, Kashyap R, Chaudhary R. Paroxysmal nocturnal hemoglobinuria clone in a case of myelodysplastic syndrome rapidly progressing to acute leukemia. Ind J Hematol Blood Transfus 2009;25:33-35 (PMID: 23449039)
  • Agarwal R, Gupta R*, Bhaskar A, Sharma A, Kumar L. Synchronous Presentation of Multiple Myeloma and Lung Cancer. J ClinOncol 2008; 26:5814-5816 (PMID: 19001336)
  • Naseem S, Gupta R*,Kashyap R, Nityanand S. T-cell prolymphocytic leukemia – A report of two cases with review of literature. Ind J Hematol Blood Transfus 2008;24(4):178-181 (PMID: 23100959)
  • Gupta R*, Pandey P, Choudhry R, Kashyap R, Mehrotra M, Naseem S, Nityanand S. A prospective comparison of four techniques for diagnosis of paroxysmal nocturnal hemoglobinuria. Internat J Lab Hematol 2007; 29:119-126 (PMID: 17474884)
  • Gupta R*, Naseem S, Kashyap R, Paul L. Role of fine needle aspirate immunophenotyping by flow cytometry in rapid diagnosis of lymphoproliferative disorders. DiagnCytopathol. 2007; 35:381-5 (PMID: 17580342)
  • Gupta R*, Naseem S, Kashyap R, Nityanand S. Immunophenotypic patterns in precursor T-cell neoplasm. Indian J PatholMicrobiol 2007; 50:75-77 (PMID: 17474267)
  • Chaudhary R, Das SS, Gupta R, Khetan D. Application of flow cytometry in detection of red-cellboundIgG in coombs-negative AIHA. Hematology 2006 ; 11:295-300 (PMID : 17178671)
  • Gupta R*, Jain P, Bakshi S, Sharma MC. Primary Hodgkin’s disease of spleen – a case report. Indian J Pathol Microbiol 2006; 49:435-437 (PMID: 17001914)
  • Sharma A, Itha S, Baijal SS, Gupta R, Sonkar A, Aggarwal R. Superior sagittal sinus thrombosis and Budd-Chiari syndrome due to paroxysmal nocturnal hemoglobinuria managed with transjugular intrahepatic portosystemic shunt: a case report. Trop Gastroenterol 2005;26:146-148 (PMID: 16512467)
  • Kashyap R &Gupta R. Extramedullary Plasmacytoma. Indian J Med & Paed Oncol 2005; 26:31
  • Gupta R*, Jain P, Anand M. Acute basophilic leukemia- a case report. Am. J Hematol. 2004; 76:134-138 (PMID: 15164378)
  • Gupta R, Jain P, Deo SVS, Sharma A. Flow cytometric analysis of CD5 positive B-cells- a frame of reference for minimal residual disease in Chrnic lymphocytic leukemia. Am. J Clin Path. 2004; 121:368-372 (PMID: 15023041)
  • Jain P, Kumar R, Anand M, Asthana S, Deo SVS, Gupta R, Bhutani M, Karak AK, Shukla NK. Touch imprint cytology of axillary lymph nodes after neoadjuvant chemotherapy in patients with breast cancer. Cancer 2003; 99:346-351 (PMID: 14681942)
  • Anand M, Kumar R, Jain P, Gupta R, Ghosal N, Sharma A, Agarwal A, Sharma M C. Metastatic anaplastic oligodendroglioma simulating acute leukemia - a case report. Acta Cytol. 2003; 47:467-9 (PMID: 12789933)

 

Book Chapters

  • Rahul Duggal, Anubha Gupta, Ritu Gupta & Pramit Mallick. “SD-Layer: Stain Deconvolutional Layer for CNNs in Medical Microscopic Imaging” in Medical Image Computing and Computer-Assisted Intervention, Lecture Notes in Computer Science, Part III, Descoteaux M., Maier-Hein L., Franz A., Jannin P., Collins D., Duchesne S (eds), MICCAI, Springer 2017; pp 435-443
  • Gupta R*& Jain P. Role of flow cytometry in plasma cell proliferative disorders. Haematology Today – 2010
  • Gupta R*. Flow cytometry and Paroxysmal Nocturnal Hemoglobinuria. Haematology Today – 2009
  • Gupta R*. Myelodysplastic syndromes in API Text Book of Medicine, Shah Siddhartha N (ed), VIII Edition, 2008

 

GEO Submisstion

Lab Oncology
Geo Submissions
  • GSE123436 miRNA profiling of CLL Contributors :Gupta R, Gupta A, Kaur G, Chaturvedi N, Rani L
  • GSE125361 Gene expression signatures in multiple myeloma Contributors: Gupta R, Mathur N, Rani L, Katiyar A, Kaur P, Kumar L, Sharma A
  • GSE125363 miRNA expression signatures in multiple myeloma Contributors: Gupta R, Mathur N, Rani L, Katiyar A, Kaur P, Kumar L, Sharma A
  • GSE81936 Methylation Profiling of IGHV Unmutated vs mutated CLL Contributors: Mathur N, Rani L, Gupta R, Gogia A, Dhanjal JK, Sunder D. Kumar L, Sharma A
  • GSE81935 Gene expression profiling of IGHV Unmutated vs mutated CLL Contributors: Rani L, Mathur N, Gupta R, Gogia A, Dhanjal JK, Sunder D. Kumar L, Sharma A

Research Project

Overview

Hematological malignancies are area of my interest and I am actively pursuing research in this area. The extramural grants received have been utilized to standardize laboratory assays for cancer research and also in setting up new assays for patient care services.Description of my over the last few years has been highlighted below.

1. Unit of excellence on cancer research on Multiple Myeloma (MM): This program aims to promote excellence in clinical laboratory practice, research and education on MM. In the era of personalized medicine where specific genomic aberrations have been linked to response and/or refractoriness to therapy, advanced genomic based tests in MM are important for assessing prognosis and imparting high quality personalized clinical care. The enhancement of current diagnostic facilities so as to achieve complete characterization of disease in each patient, development of facility to store these well-characterized samples for future research and study of genetic and epigenetic aberrations in these cancers to identify novel biomarkers for diagnosis, prediction of disease progression and response to therapy, are the focus of this unit of excellence.

2. Center of Advanced Research & Education on Acute Myeloid Leukemia (AML): AML in India has a disease burden of 2.5 cases per 100,000 and is distinct from the west because of younger age at presentation (30-40 years vs. 60-70 years in US), an advanced stage and higher early mortality during treatment. In addition, disease relapse occurs in nearly 50% of the patients of AML within the first five years and is of concern worldwide. Persistence of leukemic stem cells (LSC), which are highly divergent founder progenitors harboring heterogeneous functional, genomic, epigenomic and immunologic phenotypes, with properties of self-renewal, cell cycle quiescence and chemo-resistance, acts as the epicenter of regrowth of leukemia in treated patients of AML. The main focus of the proposed project is to characterize LSC in AML and study its micro environment which may then be used to develop appropriate therapeutic approach against them. Besides, the microtransplantation based approach for treatment of AML will be evaluated for its effect on early induction mortality, response, leukemia free survival, overall survival.

3. Minimal Residual Disease Estimation in Multiple Myeloma using Image Processing: Design and Development of Myelomaimager - an Automated Computer Assisted Tool: This study is aimed at the development of a computerized image analysis software for the classification of neoplastic plasma cells (PC) and normal PC for estimating minimal residual disease (MRD) in multiple myeloma (MM). We aim to develop a resource-effective tool for MRD detection in clinical management of MM that will benefit Indian society at large because, in general, our public hospitals and pathology labs suffer with resource shortage including skilled manpower.

4. Identification of network pathways for drug targeting in Multiple Myeloma from NGS data using Deep Learning: Most of the cancers involve intricate escape mechanisms in an individual that help malignant cells evade immune system and develop drug resistance against chemotherapy. The inherent ability of cancerous cells to continue to evolve and reach a dynamic state of physiological heterogeneity is the underlying mechanism of failure of treatment and development of relapse in patients. In this study, an integrated approach will be used to analyse genomic datasets of MM using machine learning/deep learning based computational tools to corroborate gene signatures of MM with their functional biological and pharmacological pathways at a high resolution.

Contact Us

All India Institute of Medical Sciences

Ansari Nagar, New Delhi - 110029

Board Number : +91-11-26588500 / 26588700

Fax : +91-11-26588663 / 26588641

AIIMS Exam Section Helpline numbers ( Click Here)

Important E-mail Addresses at AIIMS

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