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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Ocular Pharmacology

Department of Ocular Pharmacology Research Contributions
Malachite Green Toxicity
First reported the Ocular toxicity of Malachite green in Holi color (Hindustan times March 2006)- J Hazard Mater. 2007
Ocular drug disposition studies in progress
Indian Solar Ultraviolet Radiation Assessment Project- ISUVRA under WHO-INTERSUN Project
Corneal angiogenesis model for screening antiangiogenis compounds
Ocular drug disposition studies using concentric microdialysis probe
CADD experiments with Androgen receptors
CADD experiment to design ocular specific FQ

 

Incharge Dr.T.Velpandian Professor
Faculty Dr. Nabanita Halder, Assist. Professor

Facilities Established 

HPBAF    - High Precision Bio-analytical Lab (DST-FIST grant)

MolDyne – Molecular Dynamics Lab

OcuCel-  Cell culture facility  for invitro drug screening

NODDL –  Novel Ocular Drug Development Lab

ADD-FOND    – Adv.DrugDelv. Fac. For Ocu. Neovascular Dis.

GLP-Disp - Pharmacy (IV-Parentral dispensing Facility)                

Patient Care 

  • Nearly 30 drugs formulations for Dr. RP Centre
  •  Extemporaneously dispensed Bevacizumab Ampules (First time in India )
  •  Dispensing drugs for other Departments in AIIMS
  •  Provision to enable corneal preservation for transplantation (PECPT) – Free distribution to 45 eye banks 21 states in India (AIIMS & MHFW Initiative) 

Community Services 

  • Involved in National Security along with DRDO –Developing antidotes for Chemical warfare 
  • Taxane content analysis in Taxes  species of Himalayan region  - Tribal welfare
  •  Toxic dyes in Holi colors revealed (Malachite toxicity)
  •  Glaucoma Patient knowledge assessment and awareness program for public
  •  Two National Bio-analytical workshopsà promoting Phase I studies in India
  •  Quality of spectacle lenses available in India-Project ISUVRA (BIS)
  • Rampur Chemical Spell tragedy – Revealed
  • Pollutants in River water- Antibiotics in Yamuna water revealed 

PhD Scholars 

Student’s name

 

Research topics

MadhuNath

Evaluation of the Role of Retinal Renin Angiotensin System (RAS) in the Animal Model of Retinopathy of Prematurity (ROP)

Hanuman Sharma

Functional Importance of Nucleoside Transporters in the Ocular Disposition of their Substrates

AnkitaKotnala

Evaluation of A2E Biological Functions Relevant to the Pathology of Age Related Macular Degeneration

Moksha Laxmi

Understanding the Drug Transporter Functions in Blood Ocular Barriers during ocular inflammation in the Experimental Models of Uveitis

Ujjwalkumar Das

Developing and validating QSPR model to define enhanced drug penetration across blood ocular barriers

State-of-the-Art Facilities Available  at Ocular Pharmacology and Pharmacy

HPBAF

Neo-vasular research

NODDL-Sterile facility

MOLDYN
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