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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Dr. Sanjeev Kr. Gupta

    

 

 

Dr. Sanjeev Kumar Gupta

Additional Professor,

Laboratory Oncology, Dr B.R.A. IRCH,

All India Institute of Medical Sciences (AIIMS), New Delhi-110029. INDIA

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EDUCATIONAL QUALIFICATIONS

  • DM (Hematopathology), (2007-2010) from All India Institute of Medical Sciences (AIIMS), New Delhi
  • DNB (Pathology) (2004) from National Board of Examination, Delhi
  • MD (Pathology) (2001-2004) from Maulana Azad Medical College, New Delhi
  • MBBS (1995-2000) from Maulana Azad Medical College, New Delhi

 

FELLOWSHIP:  DHR Fellowship (2019) in the area of ‘Genomics’ at MD Anderson Cancer Centre, Houston, Texas, USA

 

 AREAS OF INTEREST:

Molecular Genetics of Hematological Malignancies, Acute Lymphoblastic Leukemia

 

CONTRIBUTIONS TO RESEARCH:

  • Dr Sanjeev Kumar Gupta has worked on the molecular genetic profile of B-acute lymphoblastic leukemia (B-ALL), particularly the gene copy number variations and their impact on clinical outcome. He published the first papers from India about the prevalence of gene copy number variations like CDKN2A/B, PAX5, ETV6, and IKAROS (IKZF1) deletions in B-ALL. This work confirmed the independent prognostic impact of IKZF1 deletions on the outcome of B-ALL and established a much higher prevalence of this adverse genetic variation in our cohort of patients.  He was awarded with the “AIIMS Excellence Research Award in 2017” for his work in this field.

 

  • Dr Gupta also studied about the complementary role of molecular genetic profile in outcome prediction of B-ALL; in addition to the standard practice of flow cytometry based minimal residual disease (MRD) assessment. He was awarded with “AIIMS Oncology Research Award in 2019” for his published work in this area.

 

  • Dr Gupta was part of an international collaborative group studying the involvement and clinical impact of COBL gene rearrangements in the B-ALL cases with IKZF1 Deletions. This work, published in Translational Oncology journal, confirmed that COBL is a hotspot associated with IKZF1 deletions but these rearrangements were not driven by RAG-mediated recombination. 

 

  • Earlier, Dr Gupta has worked on rapid diagnosis of acute promyelocytic leukemia (APML) using immunofluorescence. This approach helps in rapid confirmation of the disease and early institution of therapy, thus preventing coagulopathy related complications in patients of APML, which has to be tackled like a medical emergency. This work was quoted in the Brazilian national guidelines for the management of APML. For this research work, he was awarded “Mrs Geeta Mittal Medal, 2009” for Clinical Research at AIIMS, New Delhi.

 

  • Dr Gupta has also worked on establishing the data on prevalence of other genetic variations in Indian B-ALL patients, which are prognostically relevant, like iAMP21 (intrachromosomal amplification of chromosome 21) and ERG (ETS related gene) deletions.

 

  • Dr Gupta has evaluated the utility of various molecular diagnostic techniques like MLPA (multiplex ligation dependent probe amplification), multiplex fluorescent PCR, sequencing, Flow cytometry, FISH etc. in detecting the genetic variations in B-ALL.

 

  • Dr Gupta has also contributed towards maintaining the high standards of published research work through the peer-review process and was awarded the “Best Reviewer Award -Indian Journal of Hematology and Blood Transfusion at the 59th Annual conference of Indian Society of Haematology and Blood Transfusion, 2018” for his efforts.

 

AWARDS/ HONORS:

  1. AIIMS Oncology Research Award 2019- for outstanding publication (Clinical Research) titled, “Molecular genetic profile in BCR-ABL1 negative pediatric B-cell acute lymphoblastic leukemia can further refine outcome prediction in addition to that by end-induction minimal residual disease detection”, at AIIMS, New Delhi, 2019.
  2. AIIMS Excellence Research Award 2017- for outstanding publication (Clinical Research) titled, “Gene copy number alteration profile and its clinical correlation in B-ALL”, at AIIMS, New Delhi, 2017.
  3. Awarded long-term Fellowship in Genomics at MD Anderson Cancer Centre, Houston, Texas, USA (June- December 2019) by the Department of Health Research (DHR), Govt. of India.
  4. Best Reviewer Award -Indian Journal of Hematology and Blood Transfusion at the 59th Annual conference of Indian Society of Haematology and Blood Transfusion, 2018 at Kochi, Kerala
  5. PODC Scholarship award by International Society of the Paediatric Oncology (SIOP) to present research paper at the 49th Congress of the SIOP 2017 at Washington DC, USA,2017.
  6. UGC travel award to present research paper at the 28th annual conference of the International Society of Laboratory Hematology, ISLH 2015 at Chicago, Illinois, USA,2015.
  7. J C Patel Award for the best paper titled “Evaluation of PG-M3 antibodies in the diagnosis of acute promyelocytic leukemia” at Golden Jubilee Conference of ISHTM, at AIIMS, New Delhi, 2009.
  8. Mrs Geeta Mittal Medal, 2009 for Clinical Research at AIIMS, New Delhi.
  9. Mrs Geeta Mittal Book Prize, 2009 for Clinical Research at AIIMS, New Delhi.
  10. Pyare Lal Sharma Bishan Devi Gold Medal for Best Thesis in Pre and Para Clinical Subject for the year 2003 for thesis titled, “Evaluation of skin biopsies in leprosy for mast cells, dermal nerves and microvasculature” at Maulana Azad Medical College, New Delhi.
  11. Dr. R P Mathur Memorial Award for Best 3rd year outgoing Junior Resident in Pathology for the year 2003 in Maulana Azad Medical College, New Delhi.
  12. Dr. SN Mukherjee Gold Medal for Best Student in Obstetrics & Gynecology in the Final Professional University Exam, 1999 in Maulana Azad Medical College, New Delhi.
  13. First position in “The Quiz” of the VII National Hematology Update, at AIIMS, 2008.
  14. Award in Hindi essay-competition at AIIMS, New Delhi, 2018.
  15. Third prize in Oral paper presentation, 26th Annual Conference of Delhi Society of Hematology, Delhi, 2015.
  16. Second position in the “Hematology Quiz” at 54th Annual conference of Indian Society of Haematology & Blood Transfusion, 2013, Mumbai.
  17. Third Prize in “DM Quiz on Leukemias” in 33rd Annual Conference of Mumbai Haematology Group, at TMH, Mumbai, 2010.
  18. Second Prize for paper presentation in Young Dermatologist Session in Annual Conference of IADVL (Delhi), 2004.
  19. Certificate of Merit from Department of Education, Delhi Government, under National Scholarship Scheme in AISS Examination, 1992.
  20. All India Talent Search scholarship, 1990.

 

RESEARCH FUNDING/GRANTS:

  • Extramural research Funding by ICMR for project (I-1145; 2020-2023), “Development of risk-stratification algorithm to select BCR-ABL1 negative pediatric B-ALL patients for detailed genetic analysis- a step towards optimum use of next generation sequencing platform”
  • Intramural research project (A-600, 2018-2020), “Prevalence and significance of ETS related gene deletions in ALL”
  • Intramural research project (A-413, 2016-2018), “Prevalence of intrachromosomal amplification of chromosome 21 (iAMP21) in B-ALL”
  • Intramural research project (A-193, 2013-2015), “IKZF1 (Ikaros) mutations in B cell acute lymphoblastic leukemia”
  • ICMR Grant for DM thesis (3/2/2007-08/PG-Thesis-MPD-28) “Assessment of PNH clone by flow cytometry in Granulocytes in PNH and Aplastic Anemia” under supervision of Prof. H P Pati, AIIMS, New Delhi

 

PUBLICATIONS-

  1. Gupta SK, Viswanatha DS, Patel KP. Evaluation of somatic hypermutation status in chronic lymphocytic leukemia (CLL) in the era of next generation sequencing. Front. Cell Dev. Biol. 2020; 8:357:1-12. PMID: 32509784. doi: 10.3389/fcell.2020.00357 Published 19 May 2020 (IF- 5.180)
  2. Das N, Gupta R, Gupta SK, Bakhshi S, Malhotra A, Rai S, Singh S, Prajapati VK, Sahoo RK, Gogia A, Sharma A, Kumar L. A real world-perspective of CD123 expression in acute leukemia as promising biomarker to predict treatment outcome in B-ALL and AML. Clin Lymphoma Myeloma Leuk. 2020 Published:May 10, 2020. DOI:https://doi.org/10.1016/j.clml.2020.05.004 (IF-2.274)
  3. Lopes BA, Meyer C, Barbosa TC, Poubel CP, Mansur MB, Duployez N, Bashton M, Harrison CJ, Stadt U, Horstmann M, Pombo-de-Oliveira MS, Palmi C, Cazzaniga G, Venn NC, Sutton R, Alonso CN, Tsaur G, Gupta SK, Bakhshi S, Marschalek R, Emerenciano M. IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia. Translational Oncology, 2019; 12(5):726-732.  doi.org/10.1016/j.tranon.2019.02.002. (IF-3.071) (citations- 2)
  4. Gupta SK, Bakhshi S, Chopra A, Kamal VK. Molecular genetic profile in BCR-ABL1 negative pediatric B-cell acute lymphoblastic leukemia can further refine outcome prediction in addition to that by end-induction minimal residual disease detection. Leuk Lymphoma, 2018 Aug;59(8):1899-1904. (IF-3.093) (citations- 3)
  5. Garg S, Gupta SK, Bakhshi S, Mallick S, Kumar L. ETP-ALL with aberrant B marker expression: Case series and a brief review of literature. Int J Lab Hematol. 2019 Apr;41(2):e32-e37. doi: 10.1111/ijlh.12942. Epub 2018 Nov 8. Review. PubMed PMID: 30407727. (IF-1.919)
  6. Gupta SK, Bakhshi S, Kumar L, Kamal VK, Kumar R. Gene copy number alteration profile and its clinical correlation in B-cell acute lymphoblastic leukemia. Leuk Lymphoma, 2017;58(2):333-342. (IF-3.093) (citations- 22)
  7. Gupta SK, Bakhshi S, Kumar L, Seth R, Kumar R. IKZF1 (IKAROS) deletions in B-ALL and its clinical correlation: A prospective study from a tertiary care centre in Northern India. Leuk Res 2016;41:7-11. (IF-2.606) (citations- 9)
  8. Arora P, Gupta SK, Mallik N, Mittal R, Sharma OD, Kumar L. Flow cytometry in diagnosis of myelomatous pleural effusion: A Case Report. Indian J Hematol Blood Transfus. 2016 Jun;32(Suppl 1):138-42. Epub 2015 Sep 3. (IF-0.198) (citations- 4)
  9. Gupta SK, Chopra A, Singh S, Kumar R, Bakhshi S, Kumar L, Sharma A. Absence of CD9 expression in acute myeloid leukemia: possible correlation with t(8;21). Int J Lab Hematol. 2015; 37(3): e56-8. doi: 10.1111/ijlh.12296. Epub 2014 Sep 26. (IF-1.87) (citations- 1)
  10. Gupta SK, Sazawal S, Mahapatra M, Saxena R. Evaluation of PG-M3 antibody in the diagnosis of acute promyelocytic leukaemia. Eur J  Clin Invest 2010; 40 (10): 960–962. (IF-3.018) (citations- 5)
  11. Gupta SK, Pati HP, Tejomurtula AP, Seth T. PNH clone assessment by flow cytometry and its clinical correlation in PNH and aplastic anemia. J Hematopathol 2010; 3 (4):137–143 (IF-0.410) (citations- 3)
  12. Gupta SK, Chandramohan J, Kumar L. AML transformation after autologous stem cell transplant for multiple myeloma. BMJ Case Rep. 2015 May 29;2015. pii: bcr2015210024. doi: 10.1136/bcr-2015- 210024. (citations- 1)
  13. Gupta SK, Dass J, Saxena R. A rare case of double heterozygous state for HbD and HbE. Indian J Pathol Microbiol 2015; 58(1): 126-127.  (IF-0.642) (citations- 2)
  14. Gupta SK, Kumar R, Chharchhodawala T, Kumar L. Secondary pure erythroid leukaemia in relapsed acute lymphoblastic leukaemia: lineage switch or chemotherapy effect? BMJ Case Rep. 2014 May 19;2014. pii: bcr2013201724. doi: 10.1136/bcr-2013-201724. (citations- 5)
  15. Khera R, Gautam P, Gupta S, Arora P, Singh T, Gupta N. Adult T Lymphoblastic Leukemia (Pro-T ALL) with Reactive Monocytosis: A Case Report. Indian J Hematol Blood Transfus, 2014; 30(1):29-33. (IF-0.198) (citations- 1)
  16. Kapoor R, Pati HP, Gupta SK, Gupta N. Acute Promyelocytic Leukemia Presenting as Ischemic Stroke in Young. Indian J Hematol Blood Transfus, 2013; 29(2):93-5. (IF-0.198) (citations- 6)
  17. AggarwalS, Alam S, Khanna R, Maras JS, Gupta SK, Ahuja A. Novel nonsense mutation of ABHD5 in Dorfman Chanarin syndrome with unusual findings:A challenge for genotype-phenotype correlation. Eur J Med Genet2012;55(3):173-7(IF-2.178) (citations- 11)
  18. Sharma SK, Gupta S, Seth T, Mishra P,  Mahapatra M, Singh MK, Gupta S. Leukemia Cutis: An Unusual Presentation. Indian J Hematol Blood Transfus, 2012; 28(3): 175-177. (IF-0.198) (citations- 17)
  19. Gupta SK, Sharma M, Tyagi S, Pati HP. Transfusion induced hemoglobinopathy in patients of beta-thalassemia major. Indian J Pathol Microbiol 2011; 54: 609-11. (IF-0.676) (citations- 6)
  20. Rao S, Kar R, Gupta SK, Chopra A, Saxena R. Spectrum of hemoglobinopathies diagnosed by CE-HPLC and modulating effects of  nutritional deficiency anemia: Experience from a tertiary care centre in North India. Indian J Med Res, 2010, 132; 513-519. (IF-2.061) (citations- 61)
  21. Gupta N, Gupta SK, Jain A, Mahapatra M, Pati HP, Sarkar C. Extramedullary haematopoiesis in lymph node in a patient of T cell leukemia. Eur J Haematol, 2010; 84(6):553. (IF-2.614) (citations- 2)
  22. Gupta N, Gupta SK, Rathi S, Sharma SK, Mahapatra M, Seth T, Mishra P, Saxena R. Acute lymphoblastic leukemia presenting as non-oliguric renal failure and hypertension. Leuk Res, 2010; 34(7):e150-1. (IF-2.472) (citations- 7)
  23. Gupta SK, Rao S, Kar R, Tyagi S, Pati HP. Congenital Sideroblastic Anemia: A report of two cases. Ind J Pathol Microbiol 2009; 52(3): 424-426. (IF-0.676) (citations- 2)
  24. Gupta A, Singh U, Singh P, Kundu ZS, Gupta S, Gupta S. Fine needle aspiration of a huge pelvic mass involving the iliac bone. Cytopathology 2009; 20(1): 63-65. (IF-1.588) (citations- 1)
  25. Gupta SK, Jain D, Singh T. Plasmodium falciparum in trephine biopsy.  Am J Hematol 2008; 83(7): 602. (IF-4.671) (citations- 1)
  26. Saxena R, Gupta SK. Myeloproliferative neoplasms: The era of JAK2 mutations and more. Indian J Med Paediatr Oncol 2008; 29(4): 4-5.
  27. Jain D, Gupta SK, Singh T. Hemoglobin E disease with concomitant tuberculosis. Indian J Pathol Microbiol 2008; 51(4): 570. (IF-0.676)
  28. Gupta SK, Nigam S, Mandal AK, Kumar V. S-100 as a useful auxiliary diagnostic aid in tuberculoid leprosy. Journal of Cutaneous Pathology 2006; 33(7): 482. (IF-1.561) (citations- 19)
  29. Gupta SK, Singh S, Kumar CP, Marwah N, Gupta A. Fine needle aspiration cytology of a non ulcerated penile lump. Cytopathology 2005; 16: 312-314. (IF-1.588) (citations- 3)
  30. Nigam S, Gupta SK, Chaturvedi KU. Adenomatoid Odontogenic Tumor- A Rare Cause of Jaw Swelling. Brazilian Dental Journal 2005; 16(3): 251-253. (IF-0.283) (citations- 71)
  31. Pahwa R, Gupta SK, Singh T, Nigam S. Acute fulminant visceral leishmaniasis in children- A report of two cases. Indian J Pathol Microbiol 2004; 47(3): 428-430. (IF-0.676) (citations- 12)
  32. Singh S, Gupta R, Gupta SK , Jain S. Bilateral breast lumps in a young female- cytological approach to diagnosis. Cytopathology 2004; 15: 331-333. (IF-1.588) (citations- 3)
  33. Nigam S, Singhal N, Gupta SK, Chhabra D, Manaktala U. Placental site trophoblastic tumor in a postmenopausal female- A case report. Gynecologic Oncology 2004; 93: 550-553. (IF-3.592) (citations- 29)
  34. Pahwa R, Gupta SK, Prakash A, Singh T, Nigam S, Singh NP. Pyridoxine responsive sideroblastic anemia : A report of two cases. Indian J Hematol Blood Transfus 2003; 21(3): 90-91. (IF-0.198)
  35. 29.  Mishra D, Sharma S, Gupta S, Das M, Chauhan D. Acute Cysticercal Meningitis – missed diagnosis.  Indian J Pediatrics 2006; 73; 835-837. (IF-0.521) (citations- 4)

https://www.ncbi.nlm.nih.gov/myncbi/1TUEaZpfvbwQo/bibliography/public/

MEMBERSHIP OF SCIENTIFIC BODIES:

International societies-

  1. International Society for Laboratory Hematology (ISLH)- Member 2015-17
  2. International Society of the Paediatric Oncology (SIOP)- Member 2018
  3. Society of Hematologic Oncology
  4. Association of Molecular Pathology- Member 2019-20

National Societies-

  1. Member of National Academy of Medical Sciences (MNAMS) – admitted 2007
  2. Indian Society of Hematology & Blood Transfusion (ISHBT), 2007-Life Member No. LM-890.
  3. The Cytometry Society-India- Life member No. L-1213, (1000 renew for 14-23)
  4. Delhi Society of Haematology-Life Member No. DSH-285.
  5. Indian Association of Pathologists and microbiologists (IAPM)- Life member provisional No. OL/2015-19/1608
  6. Indian Society of Human Genetics (ISHG)- Life member no. L/1787/2015
  7. Society for Mitochondrial Research and Medicine (SMRM)-India- Life Member (L/154/2015)
  8. Indian Association of Pathologists and microbiologists (IAPM)-Delhi Chapter- Life member. 404/06

Contacts

Contact : Room No. 239, II Floor, Dr. B.R.A.IRCH, AIIMS, New Delhi, India
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone No.: 91-11-26594439 (O); 91-11-29575050; 91-11-29575048 (Lab)

GEO Submisstion

Lab Oncology
Geo Submissions
  • GSE123436 miRNA profiling of CLL Contributors :Gupta R, Gupta A, Kaur G, Chaturvedi N, Rani L
  • GSE125361 Gene expression signatures in multiple myeloma Contributors: Gupta R, Mathur N, Rani L, Katiyar A, Kaur P, Kumar L, Sharma A
  • GSE125363 miRNA expression signatures in multiple myeloma Contributors: Gupta R, Mathur N, Rani L, Katiyar A, Kaur P, Kumar L, Sharma A
  • GSE81936 Methylation Profiling of IGHV Unmutated vs mutated CLL Contributors: Mathur N, Rani L, Gupta R, Gogia A, Dhanjal JK, Sunder D. Kumar L, Sharma A
  • GSE81935 Gene expression profiling of IGHV Unmutated vs mutated CLL Contributors: Rani L, Mathur N, Gupta R, Gogia A, Dhanjal JK, Sunder D. Kumar L, Sharma A

Vacancies

Lab Oncology
Vacancies

JRF position:
Please check AIIMS website for open Ph.D.and other research positions.

Post-Doc position
Candidates who have submitted/awarded Ph.D. recently can contact to me with your CV with your specific experimental skills, instrument handling experience, and one-page write-up about your thesis work. (CV can be sent to me directly at Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Summer/project trainee (no vacancy)

Publications

2019

  • Thakral, Deepshi, et al. "Rapid Identification of Key Copy Number Alterations in B-and T-cell Acute Lymphoblastic Leukaemia by Digital Multiplex Ligation-Dependent Probe Amplification." Frontiers in Oncology 9 (2019): 871
  • Kumar L, Ramavath D, Kataria B, Tiwari A, Raj A, Chellapuram SK, Mookerjee A, Sahoo RK, Malik PS, Sharma A, Gupta R, Sharma OD, Biswas A, Kumar R, Thulkar S, for AIIMS Myeloma Group. High-dose chemotherapy followed by autologous stem cell transplant for multiple myeloma: Predictors of long-term outcome. Ind J Med Res 2019;14996):730-739.
  • Mann M, Kumar S, Chauhan SS, Bhatla N, Kumar S, Bakhshi S, Gupta R, Sharma A, Kumar L.PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix. Oncotarget 2019;10(42):4262-4275. doi: 10.18632/oncotarget.27008. (PMID: 31303961)
  • Vanidassane I, Gogia A, Raina V, Gupta R. Treatment Related Acute Myeloid Leukemia in Breast Cancer Survivors: A Single Institutional Experience. Indian J Hematol Blood Transfus 2019 Jul;35(3):561-562. doi: 10.1007/s12288-019-01078-w. (PMID: 31388274)
  • Gogia A, Gupta R, Kumar L, Sharma A, Soni L. Chronic lymphocytic leukemia with deletion 17p: An Indian scenario. South Asian J Cancer. 2019; 8(1):40. (PMID: 30766851)
  • Kaur G, Gupta R*, Mathur N, Rani L, Kumar L, Sharma A, Singh V, Gupta A, Sharma OD. Clinical impact of chromothriptic complex chromosomal rearrangements in newly diagnosed multiple myeloma. Leuk Res. 2019; 76:58-64. (PMID: 30576858)
  • Rani L, Gogia A, Singh V, Kumar L, Sharma A, Kaur G, Gupta R*. Comparative assessment of prognostic models in Chronic Lymphocytic Leukemia: Evaluation in Indian Cohort. Ann Hematol. 2019; 98:437-443. (PMID: 30338367)
  • Mittal A, Gogia A, Mallick S, Gupta R. Leukemia Cutis: A Rare Initial Presentation of Chronic Lymphocytic Leukemia. Indian J Hematol Blood Transfus 2019;35(2):367-368. (PMID: 30988580)

2018

  • Gupta A, Mallick P, Sharma O, Gupta R, Duggal R. PCSeg: Color model driven probabilistic multiphase level set based tool for plasma cell segmentation in multiple myeloma. PLoS One 2018; 13(12):e0207908 (PMID: 30540767)
  • Kashyap R, Awasthi NP, Gupta R. Clinical and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in Indian patients. J Appl Hematol 2018; 9:85-90
  • Gupta R*, Kaur G, Kumar L, Rani L, Mathur N, Sharma A, Dahiya M, Shekhar V, Khan S, Mookerjee A, Sharma OD. Nucleic acid based risk assessment and staging for clinical practice in multiple myeloma. Ann Hematol. 2018; 97(12):2447-2454. (PMID: 30056581)
  • Gupta R*, Dahiya M, Kumar L, Shekhar V, Sharma A, Ramakrishnan L, Sharma OD, Begum A. Prevalence of Monoclonal Gammopathy of Undetermined Significance in India- A Hospital Based Study. Clin Lymphoma Myeloma Leuk. 2018;18:e345-e350. (PMID: 29980412)
  • Patekar M, Gogia A, Tiwari A, Kumar L, Sharma A, Mallick SR, Sharma MC Thulkar S, Gupta R. Adult Burkitt lymphoma: An institutional experience with a uniform chemotherapy protocol. South Asian J Cancer. 2018;7(3):195-199. (PMID: 30112340)
  • Rai S, Bhardwaj U, Misra A, Singh S, Gupta R. Comparison between photostability of Alexa Fluor 448 and Alexa Fluor 647 with conventional dyes FITC and APC by flow cytometry. Int J Lab Hematol. 2018;40(3):e52-e54. (PMID: 29575796)
     

2017

  • Kumar L, Gogi L, Patel A, Mookerjee A, Sahoo R, Malik P, Sharma A, Thulkar S, Kumar R, Biswas A, Gupta R, Sharma O. Multiple myeloma with Extra medullary disease: Impact of Autologous stem cell transplantation on outcome. Bone Marrow Transplantation 2017; 52:1473-1475 (PMID: 28805789)
  • Rani L, Mathur N, Gupta R*, Gogia A, Kaur G, Dhanjal JK, Sundar D, Kumar L, Sharma A. Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia. Clin Epigenetics. 2017;9:57. doi: 10.1186/s13148-017-0356-0. (PMID:28572861)
  • Gupta R*, Kumar L, Dahiya M, Mathur N, Harry P, Sharma A,Sharma OD, Shekhar V. Minimal Residual Disease Evaluation in ASCT recipients with Multiple Myeloma. Leuk Lymphoma2017;58(5):1234-1237(PMID: 27658735)
  • Sharma A, Tilak T, Bakhshi S, Raina V, Kumar L, Chaudhary SP, Sahoo RK, Gupta R, Thulkar S. Lactobacillus brevis CD2 lozenges prevent oral mucositis in patients undergoing high dose chemotherapy followed by haematopoietic stem cell transplantation. ESMO Open. 2017;1(6):e000138. (PMID:28848667)
  • Yanamandra U, Khattry N, Kumar S, Raje N, Jain A, Jagannath S, Menon H, Kumar L, Varma N, Varma S, Saikia T, Malhotra P; for IMAGe Group. Consensus in the Management of Multiple Myeloma in India at Myeloma State of the Art 2016 Conference. Indian J Hematol Blood Transfus. 2017;33(1):15-21.PMID:28194051
     

2016

  • Gupta R*.Genomic Classification of Acute Myeloid Leukemia- An Incessantly Evolving Concept. Natl Med J India 2016;29(5):283-285 (PMID:28098084)
  • Kumar L, Boya RR, Pai R, Harish P, Mookerjee A, Sainath B, Patekar MB, Sahoo RK, Malik PS, Sharma OD, Gupta R. Autologous stem cell transplantation for multiple myeloma: Long-term results. Natl Med J India. 2016;29(4):192-199. (PMID: 28050994)
  • Sharawat SK, Raina V, Kumar L, Sharma A, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia: A prospective pilot study from India. Indian J Med Res. 2016;143(Supplement):S11-S16. (PMID: 27748272)
  • Baghmar S, Kumar L, Rani L, Mathur N, Sreenivas V, Malik PS, Tilak TVSVGK, Gupta R*. Prognostic Relevance of T Regulatory Cells in Patients with advanced-Stage Serous Carcinoma Ovary. Indian J Gynecol Oncolog 2016; 14:20.
  • Gupta R*, Chandgothia M, Dahiya M, Bakhshi S, Sharma A, Kumar L. Multi-Drug Resistance Protein 1 as Prognostic Biomarker in Clinical Practice for Acute Myeloid Leukemia. Int J Lab Hematol 2016; 38(5):e93-97 (PMID: 27321806)
  • Rani L, Mathur N, Gogia A, Vishnubhatla S, Kumar L, Sharma A, Dubey D, Kaur P, Gupta R*. Immunoglobulin Heavy Chain Variable Region Gene Repertoire and B-Cell Receptor Stereotypes in Indian Patients with Chronic Lymphocytic Leukemia. Leuk Lymphoma 2016;57(10):2389-400(PMID:26942309)
  • Nataraj V, Mathur N, Rani L, Gupta R, Bakhshi S. Serial assessment of circulating T regulatory cells and T helper 17 cells in pediatric non-Hodgkin lymphoma: a prospective study. Leuk Lymphoma 2016;57(7):1739-42 (PMID:26690272)
  • Nataraj V, Tiwari A, Mathur N, Rani L, Gupta R, Mallick S, Sharma MC, Bakhshi S. Vascular endothelial growth factor expression in pediatric non-Hodgkin lymphoma: A prospective study. PediatrHematolOncol. 2016;33(3):168-70 (PMID:27184774)
  • Chharchhodawala T, Gajendra S, Tiwari P, Gogia A, Gupta R*. Therapy related acute myeloid leukemia with t(8;16) mimicking acute promyelocytic leukemia. Indian J Hematol Blood Transfus 2016; 32:20-22 (PMID:27408347)
  • Sharma S, Arif M, Nirala RK, Gupta R, Thakur SC. Cumulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress. J Sci Food Agric. 2016;96(5):1500-1510. (PMID: 25966322)
     

2015

  • Shah B, Gajendra S, Gupta R*, Sharma A. Novel Cytogenetic aberrations in a patient of chronic myeloid leukemia with blast crisis. J Clin Diagn Res 2015; 9(5):XD05-XD06 (PMID:26155548)
  • Das A, Singh A, Gajendra S, Gupta R*, Sazawal S, Seth R. An unusual case of phenotype switch between AML FAB subtypes. Clin Case Rep. 2015;3(2):118-20. (PMID: 25767711)
  • Bahl A, Sharma A, Raina V, Kumar L, Bakhshi S, Gupta R, Kumar R. Long-term outcomes for patients with acute myeloid leukemia: A single-center experience from AIIMS, India.Asia Pac J ClinOncol. 2015; 11: 242-252 (PMID:25639656)
     

2014

  • Sharma S, Gupta R, Thakur SC. Attenuation of Collagen Induced Arthritis by Centellaasiatica Methanol Fraction via Modulation of Cytokines and Oxidative Stress. Biomed Environ Sci. 2014; 27(12): 926-938 (PMID: 25484009)
  • Gajendra S, Gogia, A, Das P, Gupta R, Tanwar P. Acute myeloid leukemia presenting as “Bowel Upset”- A case report. J ClinDiag Res. 2014; 8(7): FD09-10 (PMID: 25177572)
  • Kumar L, Iqbal N, Mookerjee A, Verma RK, Sharma OD, Batra A, Pramanik R, Gupta R. Complete response after autologous stem cell transplant in multiple myeloma. Cancer Med. 2014; 3:939-46. (PMID: 24777883)
  • Tilak T, Sherawat S, Agarwala S, Gupta R, Vishnubhatla S, Bakhshi S. Circulating T-Regulatory Cells in Neuroblastoma: A Pilot Prospective Study. PediatrHematolOncol. 2014; 31(8):717-22. (PMID:24684178)
  • Gogia A, Raina V, Gupta R, Gajendra S, Kumar L, Sharma A, Kumar R, Vishnubhatla, S. Prognostic and predictive significance of Smudge cell percentage on routine blood smear in chronic lymphocytic leukemia.Clin Lymphoma Myeloma Leuk. 2014; 14(6):514-7 (PMID: 24656596)
  • Sharawat SK, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. FLT3-ITD Mutation in Relation to FLT3 Expression in Pediatric AML: a Prospective Study from India. PediatrHematolOncol. 2014; 31(8):717-22 (PMID: 24498869)
  • Sharawat SK, Gupta R, Raina V,Kumar L, Sharma A, Iqbal S,Bakhshi R, Vishnubhatla S, Bakhshi S. Quantitative Assessment of BAX Transcript and Flow-cytometric Expression in Acute Myeloid Leukemia: a prospective study FLT3-ITD. Hematology 2014;19(7):404-11 (PMID: 24620954)
  • TilakTV,Sharawat SK, Gupta R, Agarwala S, Khan SA, Rastogi S, Sreenivas V, BakhshiS.Circulating T- regulatory cells in PNET: A prospective study. Pediatr Blood Cancer 2014;61:228-232 (PMID: 23997029)
  • Gajendra S, Gogia A, Tanwar P, Sahoo MK, Bhethanabhotla S, Durgapal P, Gupta R*. Synchronous metastatic pulmonary adenocarcinoma with small cell lymphoma. Leuk Lymphoma 2014; 55: 1678-1680. (PMID: 24073807)
  • Gogia A, Mehta P, Pramanik R, Gupta R. Chronic lymphocytic leukemia with massive ascites: An unusual presenting manifestation. South Asian J Cancer. 2014;3(4):235-6 (PMID: 25422818)
  • Gajendra S, Gupta R*,Chandgothia M, Kumar L, Gupta R, Chavan SM. Chronic Neutrophilic Leukemia with V617F JAK2 Mutation. Indian J Hematol Blood Transfus2014;30(2):139-42 (PMID: 24839370)
     

2013

  • Gajendra S, Gupta R, Gupta R*, Kumar L. Coexistence of scleroderma with multiple myeloma: a rare association. BMJ Case Rep. 2013; Sep 10; 2013. doi:pii: bcr2013200639. 10.1136/bcr-2013-200639 (PMID: 24022902)
  • Ghosh J, Singh RKB, Saxena R, Gupta R, Vivekanandan S, Sreenivas V, Raina V, Sharma A, Kumar L. Prevalence and aetiology of anaemia in lymphoid malignancies. Natl Med J India 2013; 26: 79-81 (PMID:24093980)
  • Sharawat SK, Gupta R, Raina V,Kumar L, Sharma A, Iqbal S,Bakhshi R, Vishnubhatla S, Bakhshi S. Increased co-expression of c-KIT and FLT-3 receptors on myeloblasts: independent predictor of poor outcome in pediatric acute myeloid leukemia.Clinical Cytometry2013; 84(6): 390-397 (PMID: 23740774)
  • Gogia A, Gupta R, Raina V. Disseminated tuberculosis mimicking relapse in Hairy cell leukemia. Indian J Cancer 2013;50:321
    47. Gogia A, Raina V, Gupta R. Massive ascites as apresenting feature of Plasma Cell Leukemia. Indian J Cancer 2013;50:301
  • Gogia A, Sharma A, Raina V, Kumar L, Gupta R, Kumar R. Prevalence of ZAP70 and CD38 in Indian chronic lymphocytic leukemia patients. Indian J Cancer 2013;50(4):333-336
  • Sharawat SK, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. BAX/BCL2 RMFI ratio predicts better induction response in pediatric patients with acute myeloid leukemia. Pediatr Blood Cancer. 2013; 60:E63-6 (PMID: 23553948)
  • Bhaskar A, Gupta R*, Sreenivas V, Rani L, Kumar L, Sharma A, Sharma OD, Sharma MC, Thakur SC. Synergistic effect of vascular endothelial growth factor and angiopoietin-2 on progression free survival in multiple myeloma. Leuk Res. 2013; 37:410-415 (PMID: 23332455)
  • Baghmar S, Mohanti BK, Sharma A, Kumar L, Prakash G, Kumar S, Gupta R, Kumar R, Raina V. Solitary Plasmacytoma: 10 years’ experience at AIIMS, New Delhi. Leuk Lymphoma. 2013; 54:1665-1670. (PMID: 23163525)
  • Bhaskar A, Gupta R*, Sreenivas V, Kumar L, Sharma A, Sharma MC, Prasenjit Das P, Thakur SC. Angiopoietins as biomarker of disease activity and response to therapy in multiple myeloma. Leuk Lymphoma. 2013; 54:1473-8 (PMID: 23113684)
     

2012-2003

  • Sharma A, Bahl A, Raina V, Kumar L, Gupta R. Dasatinib in chronic myeloid leukemia: A limited Indian experience. Asia-Pacific Journal of Clinical Oncology. 2012; 8:375-9 (PMID: 22897916)
  • Gogia A, Sharma A, Raina V, Kumar L, Vishnubhatla S, Gupta R, Kumar R. Assessment of 285 cases of CLL seen at single large tertiary centre from Northern India. Leuk Lymphoma. 2012; 53:1961-5 (PMID: 22475243)
  • Gogia A, Sharma A, Raina V, Gupta R. Priapism as an initial presentation of chronic lymphocytic leukemia. Leuk Lymphoma. 2012;53:1638-9 (PMID:22242818)
  • Bhaskar A, Gupta R*, Kumar L, Sharma A, Sharma MC, Kalaivani M, Thakur SC. Circulating endothelial progenitor cells as potential prognostic biomarker in multiple myeloma. Leuk Lymphoma. 2012; 53:635-40. (PMID: 21973309)
  • Naseem S, Kaur S, Gupta R*, Kashyap R, Nityanand S. Plasma Cell Leukemia: Case Series From a Tertiary Center with Review of Literature. Ind J Hematol Blood Transfus2012; 28:10-14 (PMID:23449039)
  • Ganeshan P, Gupta R*, Hakim M, Kumar L, Bhaskar A, Sharma A. Reconstitution of regulatory T-cells after autologous transplantation in multiple myeloma. Int J Hematol. 2011 ;94:578-9 (PMID:22045305)
  • Agrawal V, Gupta A, Gupta R*, Sharma MC, Das P. Nonleukemic granulocytic sarcoma of kidney with mixed phenotype blasts: A diagnostic dilemma. Indian J PatholMicrobiol. 2011; 54:606-8 (PMID: 21934235)
  • Smeeta G, Gupta R*, Sharma A, Gupta R, Gogia A. Acute myeloid leukemia with Pseudo-Chediak Higashi granules and intracytoplasmic vacuoles. Eur J Haematol. 2011 Jun 16. doi: 10.1111/j.1600-0609.2011.01668.x. (PMID: 21679254)
  • Gupta R*, Ganeshan P, Hakim M, Verma R, Sharma A, Kumar L. Significantly reduced regulatory T cell population in patients with untreated multiple myeloma. Leukemia Research 2011;35: 874-878 (PMID: 21146215)
  • Puri K, Singh P, Das RR, Seth R, Gupta R. Diagnostic dilemma of JMML coexisting with CMV infection. Indian J Pediatr. 2011; 78: 485-487 (PMID: 21193971)
  • Ghosh I, Bakhshi S, Gupta R*. Acute Basophilic Leukemia in an Infant with Proptosis. Indian J Pathol Microbiol 2011; 54: 210-211 (PMID: 21393925)
  • Agarwal R, Sreenivas V, Gupta R, Bakhshi S. Diagnostic and Follow up Eosinophilia is not Predictive of Outcome in Childhood Acute Myeloid Leukemia. J Pediatr Hematol Oncol 2011;33:e51-53 (PMID: 21285899)
  • Panda D, Gupta N, Gupta R, Bakhshi S. Pediatric myelodysplastic syndrome with cytoplasmic vacuolation in myeloid precursors. J Pediatric Hematol Oncol 2011; 33:59-61 (PMID: 21178710)
  • Agarwal P, Sekhar Das S, Gupta R, Khetan D, Chaudhary R. Quantification of Feto-Maternal Hemorrhage: Selection of Techniques for a Resource-Poor Setting. Gynecol Obstet Invest. 2010;71:47-52 (PMID: 21160194)
  • Medhi K, Raina V, Kumar L, Sharma A, Bakhshi S, Gupta R, Kumar R. Response Assessment of chronic myeloid leukemia (CML) patients receiving imatinibmesylate (Glivec) therapy: Experience from a single center in developing country. Leuk Lymphoma 2010; 51:1850-1854 (PMID: 20849386)
  • Gupta N, Kumar S.S, Gupta R*, Bakhshi S. Childhood chronic myeloid leukemia with monocytosis. Indian J Pediatr 2010; 77: 1143 (PMID: 20882436).
  • Prabhu SB, Gupta R*, Seth R. Juvenile myelomonocytic leukemia presenting with co-existent cytomegalovirus infection – A case report. J Pediatric Hematol Oncol 2010;32(4):e153-4 (PMID: 20445410)
  • Singhal M, Raina V, Gupta R, Das P. T cell-prolymphocytic leukemia detected in a patient of breast cancer at the time of recurrence: a case report. Cases Journal 2010;3:4 (PMID: 20076807)
  • Agarwal R, Gupta R*,Bakhshi S, Sharma A. Unusual cytochemical reactivity in granular acute lymphoblastic leukemia: A rare Case report. Turk J Hematol 2010;27:43-45 (PMID: 27265798)
  • Gupta R*, Bhaskar A, Kumar L, Sharma A, Jain P. Flow cytometric immunophenotyping and minimal residual disease analysis in multiple myeloma. Am J Clin Pathol 2009;132:728-732 (PMID: 19846814)
  • Ganesan P, Thulkar S, Gupta R, Bakhshi S. Childhood Aleukemic Leukemia with Hypercalcemia and Bone Lesions Mimicking Metabolic Bone Disease: Case Report and Review of Literature. J Pediatric Endocrinology and Metabolism 2009;22:463-467 (PMID: 19618667)
  • Bhaskar A, Gupta R*, Sharma A, Kumar L, Jain P. Analysis of bone marrow plasma cells in patients with solitary bone plasmacytoma. Cancer Therapy 2009;7:49-52 (PMID: 26834513)
  • Gupta N, Gupta R*, Bakhshi S. Transient myeloproliferation mimicking JMML associated with parvovirus infection of infancy. Pediatr Blood Cancer 2009; 52: 411-413 (PMID: 18989883)
  • Srivastava S, Naseem S, Gupta R*, Kashyap R, Chaudhary R. Paroxysmal nocturnal hemoglobinuria clone in a case of myelodysplastic syndrome rapidly progressing to acute leukemia. Ind J Hematol Blood Transfus 2009;25:33-35 (PMID: 23449039)
  • Agarwal R, Gupta R*, Bhaskar A, Sharma A, Kumar L. Synchronous Presentation of Multiple Myeloma and Lung Cancer. J ClinOncol 2008; 26:5814-5816 (PMID: 19001336)
  • Naseem S, Gupta R*,Kashyap R, Nityanand S. T-cell prolymphocytic leukemia – A report of two cases with review of literature. Ind J Hematol Blood Transfus 2008;24(4):178-181 (PMID: 23100959)
  • Gupta R*, Pandey P, Choudhry R, Kashyap R, Mehrotra M, Naseem S, Nityanand S. A prospective comparison of four techniques for diagnosis of paroxysmal nocturnal hemoglobinuria. Internat J Lab Hematol 2007; 29:119-126 (PMID: 17474884)
  • Gupta R*, Naseem S, Kashyap R, Paul L. Role of fine needle aspirate immunophenotyping by flow cytometry in rapid diagnosis of lymphoproliferative disorders. DiagnCytopathol. 2007; 35:381-5 (PMID: 17580342)
  • Gupta R*, Naseem S, Kashyap R, Nityanand S. Immunophenotypic patterns in precursor T-cell neoplasm. Indian J PatholMicrobiol 2007; 50:75-77 (PMID: 17474267)
  • Chaudhary R, Das SS, Gupta R, Khetan D. Application of flow cytometry in detection of red-cellboundIgG in coombs-negative AIHA. Hematology 2006 ; 11:295-300 (PMID : 17178671)
  • Gupta R*, Jain P, Bakshi S, Sharma MC. Primary Hodgkin’s disease of spleen – a case report. Indian J Pathol Microbiol 2006; 49:435-437 (PMID: 17001914)
  • Sharma A, Itha S, Baijal SS, Gupta R, Sonkar A, Aggarwal R. Superior sagittal sinus thrombosis and Budd-Chiari syndrome due to paroxysmal nocturnal hemoglobinuria managed with transjugular intrahepatic portosystemic shunt: a case report. Trop Gastroenterol 2005;26:146-148 (PMID: 16512467)
  • Kashyap R &Gupta R. Extramedullary Plasmacytoma. Indian J Med & Paed Oncol 2005; 26:31
  • Gupta R*, Jain P, Anand M. Acute basophilic leukemia- a case report. Am. J Hematol. 2004; 76:134-138 (PMID: 15164378)
  • Gupta R, Jain P, Deo SVS, Sharma A. Flow cytometric analysis of CD5 positive B-cells- a frame of reference for minimal residual disease in Chrnic lymphocytic leukemia. Am. J Clin Path. 2004; 121:368-372 (PMID: 15023041)
  • Jain P, Kumar R, Anand M, Asthana S, Deo SVS, Gupta R, Bhutani M, Karak AK, Shukla NK. Touch imprint cytology of axillary lymph nodes after neoadjuvant chemotherapy in patients with breast cancer. Cancer 2003; 99:346-351 (PMID: 14681942)
  • Anand M, Kumar R, Jain P, Gupta R, Ghosal N, Sharma A, Agarwal A, Sharma M C. Metastatic anaplastic oligodendroglioma simulating acute leukemia - a case report. Acta Cytol. 2003; 47:467-9 (PMID: 12789933)

 

Book Chapters

  • Rahul Duggal, Anubha Gupta, Ritu Gupta & Pramit Mallick. “SD-Layer: Stain Deconvolutional Layer for CNNs in Medical Microscopic Imaging” in Medical Image Computing and Computer-Assisted Intervention, Lecture Notes in Computer Science, Part III, Descoteaux M., Maier-Hein L., Franz A., Jannin P., Collins D., Duchesne S (eds), MICCAI, Springer 2017; pp 435-443
  • Gupta R*& Jain P. Role of flow cytometry in plasma cell proliferative disorders. Haematology Today – 2010
  • Gupta R*. Flow cytometry and Paroxysmal Nocturnal Hemoglobinuria. Haematology Today – 2009
  • Gupta R*. Myelodysplastic syndromes in API Text Book of Medicine, Shah Siddhartha N (ed), VIII Edition, 2008

 

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