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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Publications

PUBLICATIONS 2019-2020

Journals

  1. Patnaik U, Panda S, Thakar A ( corresponding author), Audit of Complications in an Otolaryngology led Skull Base Surgical practice, Journal of Neurological Surgery- B ( Skull Base) 2019; 80 (06), 586-592
  2. A Thakar, P Sakthivel, A  Prashanth,R Kumar, SC Sharma. Clinical Utility of 68Ga-Prostate-Specific Membrane Antigen PET/CT Scan on Postoperative Assessment of Juvenile Nasal Angiofibroma Clinical nuclear medicine  2020; 45(2):e83-e84. doi: 10.1097/RLU.0000000000002745.PMID: 31348086
  3. Panda Smriti, Thakar Alok (corresponding Author), Sikka Kapil, Sharma Suresh C, Role of Sternomastoid Muscle Interposition In Concomitant Transoral Oncologic Resection and Neck Dissection, Head & Neck  2019; 41 (8), 2724-2731
  4. Thakar Alok, Aggarwal Karan, Nasal Endoscopic Trans Sphenoidal Optic Nerve Sheath Fenestration for Intractable Intracranial Hypertension with Papilloedema–Optimism with Caution, Neurology India 2020: 68:1:61.
  5. S Panda, K Sikka, V Singh, S Agarwal, R Kumar, A Thakar, SC Sharma, Comprehensive Analysis of Factors Leading to Poor Performance in Prelingual Cochlear Implant Recipients
    Otology &Neurotology 2019; 40 (6), 754-760.
  6. Shubhi Saini, Charanjeet Kaur, Indra Pal, Punit Kumar, Tony George Jacob, Alok Thakar, KK Roy. TS Roy, Morphological development of human cochlear nucleus. Hearing Research 2019; 382, 107784. doi: 10.1016/j.heares.2019.107784. Epub 2019 Aug 20 , PMID: 31522073
  7. A Singh, DVK Irugu, K Sikka, H Verma, A Thakar, Study of Sigmoid Sinus Variations in the Temporal Bone by Micro Dissection and its Classification–A Cadaveric Study, International Archives of Otorhinolaryngology. 2019; 23 (03), e311-e316
  8. S Singh, L Singh, R Ranjan, MK Singh, A Thakar, SC Sharma Correlating the treatment outcome with tumor staging, grading, and various treatment modalities in patients with esthesioneuroblastoma, South Asian journal of cancer 2019;  8 (2), 124
  9. S Singh, R Madan, MK Singh, A Thakar, SC Sharma, Head-and-neck paragangliomas: An overview of 54 cases operated at a tertiary care center, South Asian Journal of Cancer 2019; 8 (4), 237
  10. Mittal P, Verma H, Monga R, Garg A, Thakar A, Anterior clinoid mucocele and mono-ocular vision loss – Rare case with diagnostic dilemma Interdisciplinary Neurosurgery: 2019; 19: 1000568;    DOI: https://doi.org/10.1016/j.inat.2019.100568
  11. Sakthivel, P., Singh, C.A., Thakar A, G Thirumeni, S Raveendran, Sharma SC, Masseteric-Facial Nerve Anastomosis: Surgical Techniques and Outcomes—A Pilot Indian studyIndian J Otolaryngol Head Neck Surg (2020).72:1:92-97 https://doi.org/10.1007/s12070-019-01758-
  12. Sharma SC,  Panda S,  Thakar A,  Devaraja K, Petrous Bone Cholesteatoma: Radical Excision With An Endeavour For Hearing Preservation, Indian Journal of Otolaryngology and Head & Neck Surgery 2019; 71 (2), 1572-1579
  13. H Verma, S Panda, K Sikka, DVK Irugu, A Thakar  ( corresponding author), Primary spheno-petro-clival tuberculosis, Indian Journal of Otolaryngology and Head & Neck Surgery 71 (3), 1796-1799
  14.  N Mehmi, R Kumar, P Sagar, CA Singh, R Kumar, A Thakar, SC Sharma, Importance and Impact of Appropriate Radiology in the Management of Branchial Cleft Anomalies, Indian Journal of Otolaryngology and Head & Neck Surgery 71 (1), 953-959
  15.  K Sikka, CA Singh, R Agrawal, R Kumar, A Thakar, SC Sharma, Acquired non-malignant cervical trachea-esophageal fistula: a case series,Indian Journal of Otolaryngology and Head & Neck Surgery 71 (1), 286-290
  16. A Kakkar, P Sakthivel, S Mahajan, A Thakar, Nasopharyngeal Papillary Adenocarcinoma as a Second Head and Neck Malignancy, Head and neck pathology 2019; 13 (4), 699-704
  17. K Kumari, R Thota, HL Chaudhary, MC Sharma, A Thakar, G Singh, Low-Grade Fibromyxoid Sarcoma of the External Auditory Canal: A Rare Pathology and Unusual Location, Head and Neck Pathology. 2020; 14: 276-282    doi: 10.1007/s12105-019-01030-4. PMID: 30949896
  18. C. Schafer (eds), Agarwal S, A. Thakar  ( corr. Author), Book Review “ Paediatric Audiology: Jane R. Madell, Carol Flexer, Jace Wolfe, Erin Indian Journal of Paediatrics, (2019) DOI: 10.1007/s12098-019-02973-w.
  19. Thota R, Kumar R, Kumar R, et al. Navigation-assisted endonasal endoscopic optic nerve decompression in fibrous dysplasia. BMJ CaseRep 2019;12:e230621.doi:10.1136/bcr-2019. 2)
  20. A Kairo, A Quadri, A Singh, S Sarwar, R Kumar, A Thakar, A Shariff, SC Sharma.Over expression of Psoriasin in middle ear cholesteatoma increases inflammation, bone destruction and severity of disease: Ultrastructural and molecular findings. Abstract of 27th Annual national conference of the Indian Society of Otology
  21. A Gupta, K Sikka, DVK Irugu, H Verma, AS Bhalla, A Thakar. Temporal bone meningoencephalocele and CAS leaks: experience in a tertiary care hospital. The journal of laryngology &otology 2019 Mar;133(3):192-200.
  22. Thakur R, Irugu DVK, Verma H. Osteoplastic flap approach for posterior table leak: a case report. JCDR 2019; DOI: 10.7860/JCDR/2019/41648.0000
  23. RohitVerma, Amit Jha, Shuchita Singh: Functional Near-Infrared Spectroscopy to Probe t DCS-Induced Cortical Functioning Changes in Tinnitus : J IntAdvOtol 2019, DOI: 10.5152/iao.2019.6022.
  24. Suresh Chandra Sharma, PirabuSakthivel, Shuchita Singh, Dhananjay Kumar: Boyce’s sign in a large Zenker’sdiverticulum : The Lancet : Gastroenterology and Hepatology : Vol 4, Issue 9, P742, September 1, 2019.
  25. Singh A, Thakur R, Kumar R, Verma H, Irugu DVK. Grading of the Position of the Mastoid Tegmen in Human Temporal Bones – A Surgeon’s Perspective J IntAdvOtol 2020; 16(1): 63-6 • DOI: 10.5152/iao.2020.7748
  26. Singh A, Kumar R (Corresponding Author), Manchanda S, Bhalla AS, Sagar P, Irugu DVK. Radiographic Measurement of Cochlear Duct Length in an Indian Cadaveric Population - Importance of Custom Fit Cochlear Implant Electrodes. Int Arch Otorhinolaryngol.  DOI https://doi.org/ 10.1055/s-0040-1701272.
  27. Sakthivel P, Thakar A, Prasanth A, Bhalla AS, Kakkar A, Sikka K, Singh CA, Kumar R, Sharma SC, Kumar R. Prostate-Specific Membrane Antigen Expression in Primary Juvenile Nasal Angiofibroma—A Pilot Study. ClinNucl Med  2020 Mar;45(3):195-199. doi:10.1097/RLU.0000000000002928.
  28. Zubair A, Kumar R (Corresponding Author), Jat B, Sagar P, Kairo A, Kumar R. Unusual Sites for Extracranial Head–Neck Schwannomas.  Indian J Otolaryngol Head Neck Surg. https://doi.org/10.1007/s12070-020-01820-1
  29. Singh A, Irugu DVK, Kumar R, Verma H, Gupta A, Kumari A. Study of morphologic variability of incudostapedial angle and its relation with temporal bone pneumatization, Journal of Otology, https://doi.org/10.1016/j.joto.2019.09.004
  30. Singh CA, Devaraja K, Kumar R. Recurrent Ameloblastoma: Long Term Outcomes with Free Fibular Bone Graft. Indian J Otolaryngol Head Neck Surg https://doi.org/10.1007/s12070-020-01790-4
  31. Thota R, Kumar R, Kumar R, Jat B. Navigation-assisted endonasal endoscopic optic nerve decompression in fibrous dysplasia. BMJ Case Rep 2019;12:e230621.doi:10.1136/bcr-2019.
  32. Singh A, Kumar R (Corresponding Author), Sagar P. Herald Cell: The Gateway to Posterior Tympanotomy - A Cadaveric Study. Indian J Otolaryngol Head Neck Surg. 2019 Dec;71(4):517-519. doi: 10.1007/s12070-019-01692-0. Epub 2019 Jun 26
  33. Aggarwal K, Kumar R (Corresponding Author), Bhardwaj N, Jat B, Kumar R. Isolated Laryngeal Leishmaniasis: A Diagnostic Dilemma. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):872-875. doi: 10.1007/s12070-019-01639-5. Epub 2019 Jun 1
  34. Irugu DVK, Singh A, Kumar R. Morphometry of the Digastric Ridge and Its Significance for Mastoid Surgeries-A Cadaveric Study. Ear Nose Throat J. 2019 Oct 2:145561319870491. doi: 10.1177/0145561319870491
  35. Budhiraja S, Sagar P, Kumar R, Sharma SC. Mycotic Pseudoaneurysm of Internal Carotid Artery Induced by Skull Base Osteomyelitis. OtolNeurotol. 2019 Sep;40(8):e816-e819. doi: 10.1097/MAO.0000000000002343
  36. Tripathy S, Kumar R, Kakkar A, Kumar R, Sharma P, Shamim SA. Esthesioneuroblastoma on 68Ga DOTANOC PET/CT. ClinNucl Med. 2019 Aug; 44(8):e486-e488. doi: 10.1097/RLU.0000000000002644
  37. Gupta N, Kumar R, Soneja M, Singh G, Khot W, Malla S, Xess I. Mucor menace in an immunocompetent young male after dental manipulation. J Family Med Prim Care. 2019 Feb;8(2):757-759. doi: 10.4103/jfmpc.jfmpc_412_18
  38. Devaraja K, Kumar R (Corresponding Author), Sagar P, Barwad A. Intraductal pseudopodia in pleomorphic adenoma of parotid gland. Indian J PatholMicrobiol 2019;62:117-8
  39. SmitaManchanda, AshuSeithBhalla, Rakesh Kumar, Arvind Kumar Kairo Duplication Anomalies of the Internal Auditory Canal: Varied Spectrum; Indian J Otolaryngol Head Neck Surg, 71 (3), 294-298 Sep 2019
  40. Punj J, Kaler P, Ankalagi B, Prasad A, Sinha R, Sagar P. Successful anaesthesia management of a child with hunter syndrome for adenotonsillectomy. Intractable Rare Dis Res. 2019 Nov; 8(4): 286–288.doi: 10.5582/irdr.2019.01072
  41. Sakthivel P, Thakar A, Prasanth A, Bhalla AS, Kakkar A, Sikka K, Singh CA, Kumar R, Sharma SC, Kumar R. Prostate specific membrane antigen expression in Primary Juveline Nasal Angiofibroma- A Pilot Study. Clinical Nuclear Medicine (Accepted)
  42. Bindra A, Pathak S, Sikka K. Split Larynx. Anesthesiology. 2019 Jun 24. doi: 10.1097/ALN.0000000000002867. [Epub ahead of print]
  43. Thakar A, Sikka K (2019). Transoral Laser Microsurgery. In Bahadur S, Thakar A, Mohanty BK. Carconoma of the Larynx and Hypopharynx (1st ed; 99-110 Singapore, Springer)
  44. Panda S, Sikka K, Thakar A, Sharma SC, Krsihnamurthy P. Transoral robotic surgery for the parapharyngeal space: expanding the transoral corridor. J Robot Surg 2019 (Ahead of print)
  45. Rajeshwari M, Sakthivel P, Sikka K, Jain D. Carcinoma encuirasse in Neck: extremely unusual initial presentation of gastric cancer. BMJ Case Reports CP 2019;12:e228418
  46. Sakthivel P, Sikka K, Kakkar A, Kavutharapu S, Thakar A. Polypoidal Trachea: A Clinican’s Predicament. Am J Med 2019; 132 (3): 523-4
  47. Singh CA, Sakthivel P. Rhinosporidiosis. New England Journal of Medicine. 2019; 380:1359. DOI: 10.1056/NEJMicm1811820
  48. Kaur K, Kakkar A, Bhardwaj N, Sakthivel P, Singh CA, Jain D, Mathur SR, Iyer VK, Sood R. Spectrum of cytomorphological features of extranodal NK/T-cell lymphoma, nasal type. Cytopathology. 2019 Jul;30(4):393-401. doi: 10.1111/cyt.12705.
  49. Panda S, Kumar R, Konkimalla A, Thakar A, Singh CA, Sikka K, Sharma SC, Kakkar A, Bhasker S. Rationale behind thyroidectomy in total laryngectomy: analysis of endocrine insufficiency and oncological outcomes. Indian J SurgOncol. 2019 Dec;10(4):608-613. doi:10.1007/s13193-019-00935-4.
  50. Kanodia A, Sakthivel P, Singh CA, Rajeshwari M. Strawberry nose and rhinosporidiosis. QJM. 2020 Jan 1;113(1):64-65. doi:10.1093/qjmed/hcz132.
  51. Rewari V, Ramachandran R, Singh CA. [Awake nasal fibre optic intubation --- a simple manoeuvre for easy navigation of the fiberscope through the nasopharynx]. Rev Bras Anestesiol. 2019 Nov - Dec;69(6):641. doi: 10.1016/j.bjan.2019.06.011.
  52. Kakkar A, Bhardwaj N, Sakthivel P, Singh CA, Jain D, Mathur SR, Iyer VK. Fine needle aspiration cytology of cribriform adenocarcinoma of minor salivary gland, a recently defined entity. Cytopathology. 2019 Nov;30(6):662-666. doi:10.1111/cyt.12750.
  53. Sarangi J, Kakkar A, Roy D, Thakur R, Singh CA, Sharma MC. Ocular non-teratoidmedulloepithelioma with teratoid metastases in ipsilateral intraparotid lymph nodes. Eur J Ophthalmol. 2019 Aug 14:1120672119870079. doi:10.1177/1120672119870079.
  54. Chandran A, Sakthivel P, Singh CA. A Swollen Nose - Nasal Septal Hematoma.Indian J Pediatr. 2020 Jan;87(1):88. doi: 10.1007/s12098-019-03052-w.
  55. Chandran A, Sakthivel P, Chirom AS. Quincke's disease. BMJ Case Rep. 2019 Sep 11;12(9). pii: e231967. doi: 10.1136/bcr-2019-231967.
  56. Sakthivel P, Thakar A, Prashanth A, Bhalla AS, Kakkar A, Sikka K, Singh CA, Kumar R, Sharma SC, Kumar R. Prostate-Specific Membrane Antigen Expression in Primary Juvenile Nasal Angiofibroma-A Pilot Study. ClinNucl Med. 2020 Mar;45(3):195-199.  doi: 10.1097/RLU.0000000000002928.
  57. Rajeshwari M, Sakthivel P, Yogal R, Panda S, Singh CA, Jain D. Composite tumor of the larynx: A Case Report. JNMA J Nepal Med Assoc. 2020 Jan;58(221):52-55. PubMed PMID: 32335641.

 

ABSTRACTS PUBLISHED IN JOURNALS

 

  1. 1.      Assessment of depth of invasion in tongue squamous cell carcinoma (T1-T3) by clinical palpation & radiology and their correlation to histopathological depth of invasion. Rajeev Kumar, Mohammad Ponneth, SmitaManchanda, AdarshBarwad,PremSagar, Chirom Amit Singh, AshuBhalla. J Head Neck Physicians Surg 2019 Oct; 7 (Suppl): ABS-087
  2. 2.      A Biswas, L Kashyap, S Roy, R Sahoo, R Pramanik, K Sikka, S Bhasker, Sharma, A; Thakar, A; BashiS..Multi-Modality Management of Nasopharyngeal Carcinoma in Paediatric and Adolescenet Patients: Experience from a Regional Cancer Centre in North India. PEDIATRIC BLOOD & CANCER 66, S124-S124
  3. 3.      AK Kairo, JA Quadri, A Singh, S Sarwar, R Kumar, A Thakar, A Shariff, Over Expression of Psoriasin in Middle Ear Cholesteatoma Increases Inflammation, Bone Destruction, and Severity of Disease: Ultrastructural and Molecular Findings. Annals of Otology and Neurotology 2 (01), A006

BOOK CHAPTERS

 

S. No.

Author(s) of chapter

Chapter title

Name of editor

Name of the book

Edition

City of publication

Publisher

Year of publication

First-Last page

1

Pirabhu S, Mittal P, Thakar A (corresponding author)  ( in press)

 

Vagal Paraganglioma and Shwannoma,

 

Eds.Gooi Zhen & Agarwal Nishant,

Difficult Decisions in Head and Neck Oncologic Surgery

 

New Delhi

Springer

2019

Print version awaited)

2

Sikka K, Thakar A.  

Vascular Compression Syndrome and Vertigo

Santosh K Kacker

Complicated Cases in Vertigo and Dizziness

2nd

New Delhi

Kontentworx

2019

138-140 

3

Pirabhu S, Mittal P, Thakar A

Difficult Decisions in Head and Neck Oncologic Surgery

Gooi Zhen & Agarwal Nishant

Difficult Decisions in Surgery: An Evidence-Based Approach 

1

 

Springer

2019

185-205.

 

 

 

 

Format: Author of chapter. Chapter title. In: Name of editor(s). Name of the book (in italics). Edition. City of Publication: Publisher; Year: first page-last page.

 

  1. 1.      List of edited books and monographs.

 

Books

 

Book Review  – Rhino sinusitis with nasal polyposis (IJMR Book Reviews).

–  Surgical Content Editor ‘Sinonasal Imaging’ (Clinico Radiological Series)

Other Facilities

Other Facilities                                                                                                                                                

  1. REHABILITATION UNIT OF AUDIOLOGY AND SPEECH THEARPY

This unit provides comprehensive diagnostic and rehabilitative services in various speech and hearing disorders which include diagnostic audiology services, hearing therapy & hearing aid fitting & rehabilitation & speech therapy & training.

The unit is equipped with state of the art equipment and houses facilities for diagnostic audiometry, tympanometry, evoked response testing, hearing aid calibration, ear mould lab, play therapy, stroboscopy & computer aided speech analysis with VAGHMI & vocal-2, speech analysis with software.

Consultations with clinical experts in the unit are available every working day morning. All patients seen in the unit should however have had a previous consultation with the ENT medical staff. The unit has developed expertise in detection & evaluation of paediatric hearing impairment & with its rehabilitation & therapy. The facilities for cochlear implant programming, behavioural assessment and Neural response telemetry are available in the cochlear implant lab. The speech therapy services provide therapy for stammering, misarticulating, voice disorder, post laryngectomy, aphonia, cleft palate, and patients with hearing impairment.

  1. 2.       RHINOLOGY & ENDOSCOPIC SKULLBASE SURGERIES
  2. 3.       SLEEP SURGERIES

The department also have advance instruments to manage cases of nose, paranasal sinus & skull base masses (Endoscopes, Coablator, Microdebrider, Navigation system, Radio-frequency ablation, Endoscopic drill, Carotid Doppler, CUSA, bone Saw). The department is also doing skullbase lesion. The department is operating angiofibroma, CSF leaks, transorbital excision of lesions, fungal sinusitis, choanal atresia, tumour of sino-nasal region etc on regular basis. The department is doing other extended endoscopic approaches with Neurosurgery team.

For localization of lesion in Obstructive sleep apnoea, the department have Apneography, Rhinomenometry.  DISE & sleep MRI are performed in collaboration with other Departments. The department is doing, tonsillectomy, adenoidectomy, expention procedures

Research

Research 2019-2020

Funded projects

Ongoing

S. No.

Title of the project

Name of Principal Investigator

Funded by (Name of funding agency)

Duration (years)

Start year – End year

Total funds sanctioned (Rs)

1

Prevalence & Etiology of hearing impairment- National Task Force project (Coordinating Centre)

Alok Thakar

Indian Council of Medical Research

4 Years

2015-2019

Rs. 97

lakhs

 


2

Prevalence of human papilloma virus in head-neck squamous cell carcinoma (AIIMS Site)

Alok Thakar

Head Neck Co-operative Oncology Group (HNCOG)

2 Years

2015-ongoing

Unfunded

3

Evaluation of machine learning techniques including deep learning for the identification of Malignancy in tissue samples.

Alok Thakar

Dr. Aanchal Kakkar ( Pathology- PI)

AIIMS- IIT Delhi Joint Collaborative Funding

2 Years

2019-ongoing

 

4

3D Printed Tracheal grafts for Regenerative application

Alok Thakar

Dr. Sujata Mohanty (Stem Cell Facility- PI)

AIIMS- IIT Delhi Joint Collaborative Funding

2 Years

2019-ongoing

 

5

Molecular Characterization of Olfactory  Neuroblastomas for classification into prognostically and therapeutically relevant subgroups

Alok Thakar

Dr. Aanchal Kakkar ( Pathology- PI)

DST (SERB) 

3 Years

2020-Ongoing

 

6

Effects of non-ionizing electromagnetic field on human health: effects on auditory and vestibular system

Dr Rakesh Kumar

ICMR

3.5 years (extended)

 

Rs 90 lakhs

7

Sound4All: Re-engineering High-end Audiometric Devices for Robust and Affordable Audiological Testing Phase 2

Dr Kapil Sikka

Indo German Science and Technology Center (IGSTC)

3 Years

2019-2022

54 Lakhs

8

Factors impacting outcomes of Cochlear Implants in Pediatric population

Dr Kapil Sikka

ICMR

3 years

2019-2022

28,4000

9

The Clinicopathological evaluation of Cholesteatoma aggressiveness

Kapil Sikka

AIIMS

2 years

2018-2020

6.5 Lakhs

10

Study of  Human Papilloma Virus (HPV) Association in Sinonasal Tumors

Kapil Sikka

AIIMS

2 years

2018-2020

20 Lakhs

11

Evaluation of unknown head and neck primaries metastatic to cervical lymph nodes

 

Chirom Amit Singh

AIIMS

2 years

2018-2020

4.95 lakhs

12

Evaluation of genetic profile of olfactory neuroblastoma

Rajeev Kumar

AIIMS

2 years

2018-2020

Rs 10 lakhs

13

An evaluation of HLA, phagocytic function and trace elements in cases of sinusitis, invasive fungal sinusitis and non-invasive fungal sinusitis

HITESH VERMA

AIIMS

2 Years

2019-2021

10 LACS

14

Development of single-cell derived clonal spheroids as a tool for drug discovery in cancer research with focus on Head and Neck Cancer

HITESH VERMA

ICMR

3 Years

2019-2022

3 CRORE

15

Salivary micro-RNA: Their utility as bio-marker during molecular changes in tobacco users vs. tobacco non-users

Shuchita Singh

AIIMS

2 years

2016-18

9.8 lakhs

16

 

Study of Inner Ear Protein Otolin-1, Vitamin D and Ionized Calcium in circulation as a biomarker in non-Meniere’s disease vertigo patients

 

David Victor Kumar Irugu

AIIMS

2 years

2018- 2020

8.66 lakhs

17

pilot   comparative   study   on   expressional   level   difference   of

‘psoriasin’  between   different   squamous   ear   diseases   in   patients   undergoing

mastoid surgeries

BRCC3 Expression as a prognostic marker in Oropharyngeal Carcinoma Patients and its effect on radiotherapy resistance

Arvind Kumar Kairo

AIIMS

2 years

2018-2020

9.05 lakhs

18

Prevention of Radiotherapy Induced Xerostomia by intraductal administration of N- Acetyl

Dr Arvind Kumar Kairo

ICMR

3years

2020- 2023

 

 

36 lakhs

 

Completed

 

1

To elucidate the functional relevance of Sin3B mRNA alternate splicing in pathogenesis of oral squamous cell carcinoma (OSCC)

S.C. Sharma

Science and Engineering Research Board (SERB)

2 Years

2017-2019

3.55 Lakhs

2

Evaluation of level of Vascular Endothelial Growth Factor’ – in cases of Recurrent Respiratory Papillomatosis

Hitesh Verma

AIIMS

2 years

2016-18

4.7 lakhs

3

Clinical and biochemical evaluation for depression in patients with recently diagnosed head and neck cancer

 

DrPremSagar

AIIMS

3 Years

2016-2019

8 lakhs

Departmental projects (including thesis/dissertations)

Ongoing

S. No.

Title of the project

 1

Allogenic tissue engineered tracheal transplantation in wistar rats – preclinical study

 2

To evaluate the role of transnasal esophageal endoscopy for detection of synchronous esophageal neoplasm in head and neck cancer patients

 3

Impact of OSMF on Occult and Overt lymph node metastasis in Gingivobuccal complex carcinoma of Oral Cavity- A prospective study

 4

Design and development of Tracheoesophageal prosthesis for improved deployment and voice rehabilitation in post-laryngectomy patients.

 5

Parathyroid identification in thyroid surgery by naked eye evaluation, microscopic evaluation and by near infrared fluorescence using indocyanine green

 6

Evaluation of clinical features and treatment outcomes in patients with Skull Base Osteomyelitis

 7

Evaluation of serum Otolin 1as biomarker and significance of serum vitamin D in BPPV Patients

 8

Comparison of different cochlear implantation outcome scores with auditory cortical activity seen on fNIRS in prelingual profound SNHL patients atleast 3 years after cochlear implantation

 9

Severity of OSA- An evaluation with effect of surgery by inflammatory markersand correlation with anatomical factors

 10

Evaluation of fat implantation in patients with sulcus vocalisandvideolaryngostroboscopic assessment before and after treatment

 11

To determine the incidence of paratracheal lymph node metastasis in patients with carcinoma larynx and hypopharynx planned for partial/ Total Laryngectomy

 12

Outcomes of patients undergoing same stage pinna reconstruction and canalplasty

 13

Coblation assisted endoscopic excision of juvenile nasopharyngeal angiofibroma: a prospective pilot study

 14

Survival outcomes and quality of life evaluation for surgically treated oral cavity carcinoma patients

 

Completed

S.No.

Title of the project

 1

Assessment of depth of invasion in oral cavity squamous cell carcinoma(T1-T3) by clinical palpation and radiology and their correlation to histopathological depth of invasion

 2

Study of microvascular density and tumour associated macrophages in oral squamous cell carcinoma

 3

A prospective study to explore patterns of nicotine dependence in newly diagnosed cases of head and neck squamous cell carcinoma and evaluate its association with perioperative complications

 4

Outcome in patients undergoing surgical correction of microtia

 5

Evaluation of various clinical and immunological parameters in predicting the outcomes of sinonasal and skull base invasive fungal diseases: A descriptive study

 6

A pilot study on the causal relationship of gastroesophageal reflux and obstructive adenoid or adenotonsillar hypertrophy in paediatric population

 7

SDH-X mutation in head and neck paragangliomas: A clinicopathological study 

 8

Effect of short term endotracheal intubation on laryngeal function

 9

Clinico radiological correlation of severity of disease with vit D and immune markers in cases of allergic rhinitis and nasal polyposis

 10

Comparison of post cochlear implant outcomes in children with inner ear malformation vs normal anatomy

 11

Prospective pilot study to evaluate the incidence of lymph node metastasis in olfactory neuroblastoma

 12

EMG findings in dysphonia due to laryngopharyngeal reflex disease and correlation with treatment outcome: an observational study

 13

To correlate functional near infrared spectroscopy measurement of auditory cortex activation with auditory verbal outcome in prelingual profound sensorineural hearing loss patients after cochlear implantation

 14

Assessment of clinical profile in patients of Menieres Disease and Vestibular Migraine

 15

Exploration of first echelon lymph node drainage of squamous cell carcinoma of tonsil with reference to lateral retropharyngeal lymph node of rouviere

 16

Role of 68 gapsmahbed cc scan in patients with juvenile nasal angiofibroma S

 17

Assessment of host immunological tumour response byhistochemistry in cancer oral cavity and its impact on prognosis –retrospective cohort study

18

A prospective study to determine the efficacy of PET-CT scan in determining residual disease in locally advanced head and neck squamous cell carcinoma managed with primary chemoradiotherapy (Department of Nuclear Medicine)

19

 

A pilot study to assess the therapeutic potential of Lu- 177 DKFZ- PMSA 617 in Ga-68 PSMA HBED CC PET-CT positive anaplastic thyroid carcinoma (Department of Nuclear Medicine

 

Collaborative projects

Ongoing

S. No.

Title of the project

Collaborating department/institution

 

 1

Interdisciplinary variations in the spectrum of oral mucosal lesions

Dermatology

 

 2

Pilot study on comparison of efficacy and usability of indigenous handheld suction assembly for pediatric tracheostomised patients with the existing suction devices

Pediatrics

 

 3

Developing suctioning machine for cleaning tracheostomy tubes

IIT Delhi

 

 4

“Cleft Lip and Palate anomaly in India:  Clinical profile Risk factors and current status of treatment:  A hospital based study”

Co-Investigator: Prof SC Sharma

Centre for Dental Education and Research

 

 

 5

Serum Zinc levels in Indian population with chronic idiopathic tinnitus

Pharmacology

 

6

A longitudinal Survey to assess Patient Satisfaction for Nurse Initiated Follow Up Tele-Consultation among patients discharged from a selected tertiary care hospital

Nursing

 

7

An OMR sheet based feed-back survey on in-patient satisfaction regarding various hospital services in a selected tertiary care hospital

College of Nursing

 

8

Phenotypic and genotypic characterization of non-typeableHaemophilusinfluenzae (NTHi) from North India       

Microbiology

 

9

A Study of nasopharyngeal carriage of Haemophilus influenza in north Indian population

Microbiology

 

10

Fluorosis mitigation in scheduled caste community of Bihar through intervention and counselling

Anatomy

 

11

Pilot study on comparison of efficacy and usability of indigenous handheld suction assembly for paediatric tracheostomised patients with the existing suction devices

Department of Otolaryngology & Head Neck Surgery and Department of Paediatrics, AIIMS, New Delhi

 

12

Clinico-radio-pathological evaluation of different possible primary sites in cases of FNAC proven SCC of lymph node in head and neck malignancy

Department of Otolaryngology & Head Neck Surgery, Department of Radio-diagnosis, Department of Pathology, AIIMS, New Delhi

 

13

Role of ultrasound in predicting the depth of tumour invasion and lymph node metastasis in early tongue carcinoma

Department of Otolaryngology & Head Neck Surgery, Department of Radiology, AIIMS, New Delhi

 

14

Evaluation of split- bolus dual energy CT in staging of carcinoma larynx (Department of Radiodiagnosis)

Radiodiagnosis

 

15

Evaluation of WNT and SHH signalling pathways in olfactory neuroblastomas (Department of Pathology)

Department of Pathology, Department of Otolaryngology- Head Neck Surgery, Dept. of Medical Oncology

 

16

To compare the functioning of delayed surgical obturator fabricated using conventional and vacuum formed method in maxillectomy patients: a randomized control study ( Department of Prosthodontics)

Pathology

 

17

To evaluate the role of Kit-based Loop-Mediated Isothermal Amplification (TB-LAMP) assay in the diagnosis of Extra-pulmonary tuberculosis (EPTB)

Medicine

 

Patient Education

Patient Care

Patient Care

  1.     COCHLEAR IMPLANT PROGRAM (an overview)

The cochlear implantation (CI) program was started in All India Institute of Medical Sciences in 1996 under the chairmanship of Prof.RC Deka and the first adult patient was successfully operated upon in February  1997. Soon, the department started the Children Program in 1998. Till now (Feb 2020), we have performed 414 cochlear implant surgeries in adults and children. The department has provided support in starting a cochlear implant program in R.R. Hospital, Central Railway Hospital in New Delhi, and also PGIMER in Chandigarh.

What is a cochlear implant?

A cochlear implant is an electronic device that restores partial hearing to the deaf. It is the only treatment option available for patients with bilateral profound sensorineural hearing loss if there is no benefit with hearing aids.

How does a cochlear implant work?
A cochlear implant is surgically implanted in the ear and activated by a device worn behind the ear. It converts sound to electrical impulses. These impulses are then transmitted via hearing nerve to the brain. The device bypasses damaged parts of the auditory system (hair cells of the cochlea) and directly stimulates the nerve of hearing, allowing individuals who are profoundly hearing-impaired to perceive sound.

What are the components of Cochlear Implant?

Cochlear implants have two parts -:

a. external (outside) parts that include a microphone, a speech processor, and a transmitter.

b. internal (surgically implanted) parts - a receiver-stimulating system fixed to the skull bone behind the ear and electrodes which are inserted into the cochlea

 

 

 

 

 

 

 

 

 

 

 

 The microphone picks up sounds and sends them to the speech processor. The speech processor analyzes and digitizes the sound signals and sends them to a transmitter worn on the side of the head just behind the ear. The transmitter sends the coded signals to an implanted receiver. The receiver in turn delivers them to the array of electrodes that stimulate the fibers of the auditory nerve directly. The auditory nerve transmits this information to the brain where it is interpreted as meaningful sound and thus the implanted person starts learning language and speech communication skills.

Cochlear Implant surgery in AIIMS

An implant team consisting of Otolaryngologist, Audiologist, Radiologist, Pediatric Neurologist, Clinical Psychologist and Speech Therapist does the clinical and other laboratory assessment before planning for surgery. Implant surgery is performed under general anesthesia and lasts from two to three hours. The procedure requires a stay in the hospital for 7 to 10 days. 

Postoperative rehabilitation

The postoperative rehabilitation will be done by the rehabilitation team consisting of Otolaryngologist, Audiologist and Speech Therapist. Parents’ participation in the training is of paramount importance and one of the parents has to learn the therapy to train the child at home. When the surgical wound is well healed (usually 3 to 4 weeks after surgery) the cochlear implant is activated (switch-on) and a MAP is created using computer based software. The subsequent mapping sessions are individually tailored as per the progress made by the patient. The short and long term goals are set for listening and then language and speech. The therapist teaches the child to listen to the sound that is received from the cochlear implant and helps them in the developing effective spoken communication, leading to development of language and speech. 

When my child/ the patient start hearing and speaking?

Cochlear implants do not restore normal hearing, and benefits vary from one individual to another. The implantees are expected to hear and/or recognize sounds/speech and learn language through the auditory input with the help of a cochlear implant. In children, 4-5 years of intensive training is needed.

Contact Us

All India Institute of Medical Sciences

Ansari Nagar, New Delhi - 110029

Board Number : +91-11-26588500 / 26588700

Fax : +91-11-26588663 / 26588641

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Important E-mail Addresses at AIIMS

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