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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Research

Research

The department is actively engaged in extramural and intramural research projects over the past many years. The department has been recognized as a Unit of Excellence for Cancer Research in Multiple Myeloma by Department of Biotechnology.

 

Extramural Research Projects

  1. Molecular analysis of cytogenetically normal acute myeloid leukemia; Dr. Rajive Kumar
  2. Unit of Excellence on Cancer Research on Multiple Myeloma; Dr. Ritu Gupta
  3. Minimal Residual Disease Estimation in Multiple Myeloma using Image Processing: Design and Development of Myelomaimager- an Automated Computer Assisted Tool; Dr. Ritu Gupta
  4. Resistance to tyrosine kinase inhibitors in Indian patients with chronic myeloid leukemia-a mechanistic view; Dr. Ritu Gupta
  5. Design and Development of Leukoanalyzer, an Automated Computer Assisted Tool, for Minimal Residual Disease Estimation (MRD) in B-Lineage Acute Lymphoblastic Leukemia (ALL) using Image Processing Techniques; Dr. Ritu Gupta
  6. Elucidation of pathologically relevant miRNAs responsible for disease progression and resistance to chemotherapy in CLL; Dr. Ritu Gupta
  7. Interrogating the myeloma genome with reference to microRNAs modulated gene expression; Dr. Ritu Gupta
  8. Prognostic Relevance of DNA methylation in chronic lymphocytic leukemia; Dr. Ritu Gupta
  9. Th17 cells in pathobiology of multiple myeloma; Dr. Ritu Gupta; Natural Killer & T-lymphocyte Subset Analysis in Multiple Myeloma; Dr. Ritu Gupta
  10. Molecular & immunological basis of biological heterogeneity in CLL; Dr. Ritu Gupta; HIF-1α as regulator of angiogenesis in multiple myeloma; Dr. Ritu Gupta
  11. Regulatory T-Cell repertoire in plasma cell myeloma; Dr. Ritu Gupta
  12. Immunophenotypic characterization of plasma cells by flow cytometry in health & disease with particular reference to plasma cell myeloma; Dr. Ritu Gupta
  13. Early immature T- lymphoblastic leukemia (ALL): evaluation of early thymic precursor T-ALL immunophenotype, absence of biallelic deletion of TCR γ chains (ABD) and expression of MEF2C as predictors of treatment response as assessed by minimal residual disease determination; Dr. Anita Chopra
  14. Evaluation of  expression of  FGFR1, FGFR2 , Cyclin D1 & PIK3CA  and PIK3CA  mutations  in of Hormone Receptor(Estrogen & Progesterone ) positive and HER2 receptor negative cases of primary breast cancer; Dr. Pranay Tanwar
  15. A prospective study to evaluate WT1 gene expression as predictive molecular marker of disease progression in de novo cases of Acute myeloid Leukemia; Dr. Pranay Tanwar
  16. Comparative study of Genetic, Clinical and Epidemiological factors of Breast Cancer in Indian population; Dr. Pranay Tanwar
  17. Evaluation of HE4 level in epithelial ovarian cancer for diagnosis & monitoring of therapy; Dr. Amar Ranjan Singh
  18. Role of NFKB1 gene function in hematological diseases; Dr. Gurvinder Kaur

 

 

Intramural Research Projects

  1. Development of laboratory algorithm for molecular classification of Multiple Myeloma in clinical practice; Dr. Ritu Gupta
  2. Towards a comprehensive molecular score in CLL; Dr. Ritu Gupta
  3. Assessment of multi-drug resistance pattern in acute myeloid leukemia and response to therapy; Dr. Ritu Gupta
  4. Prevalence of intrachromosomal amplification of chromosome 21 (iAMP21) in B-ALL; Dr. Sanjeev Kumar Gupta
  5. IKZF1 (Ikaros) mutations in B cell acute lymphoblastic leukemia; Dr. Sanjeev Kumar Gupta
  6. Detection of minimal residual disease in T-lineage acute lymphoblastic leukemia by a low-cost PCR analysis of clonal T-cell receptor gene rearrangement; Dr. Anita Chopra
  7. Molecular determinants of prednisolone sensitivity in pediatric acute lymphoblatic leukemia; Dr. Anita Chopra
  8. A prospective study to evaluate Wilm’s tumor 1 (WT1) mutation in de novo cases of Acute myeloid Leukemia and correlating their outcome  with treatment response; Dr. Pranay Tanwar
  9. Evaluation of Thrombopoietin as a marker of sepsis in post operative cases of gastrointestinal malignancy; Dr. Amar Ranjan Singh

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All India Institute of Medical Sciences

Ansari Nagar, New Delhi - 110029

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