vThe future of medicine lies in understanding how the body creates itself out of a single cell and the mechanisms by which it renews itself throughout life.
vWhen we achieve this goal, we will be able to replace damaged tissues and help the body regenerate itself, potentially curing or easing the suffering of those afflicted by disorders like heart disease, Alzheimers, Parkinson’s, Diabetes, Spinal cord injury and Cancer.
vResearch at the facility leverages many strengths in a way that promotes that goal. The Facility brings together experts from a wide range of scientific and medical fields to create a fertile, multidisciplinary research environment.
vDifferentiation of human mesenchymal stem cells: Researcher is expanding their understanding of human mesenchymal stem cells differentiation into functional cardiomyocytes and dopaminergic neurons by using different cocktails of the growth factors and chemicals.
vTissue regeneration from transplanted mesenchymal stromal cells (MSC) either through transdifferentiation or cell fusion was originally proposed as the principal mechanism underlying their therapeutic action. Identifying key MSC-secreted factors and their functional role seems a reasonable approach for a rational design of next generation MSC-based therapeutics.span>
vMitochondrial transfer techniques have the potential to provide patients with novel reproductive options for the prevention of mtDNA disease
Tissue engineering is an emerging field that aims at regeneration of natural tissues and the creation of new tissues using a combination of cells, biomaterials, biotechnology, engineering, and clinical medicine.
Scaffold: Chitosan, hydroxyapatite, Poly-Caprplactone
Properties: Bio –compatible, Osteo-conductive, comprehensive strength
In vivo studies- Good osteogenic potential, No inflammation
Scaffold: Plasma PCL
Properties: Biocompatible, Good transparency, Biodegradable, Mechanical Strength
In vivo study: Alkali burn rabbit model, Good healing, No immunological reactions
Ocular Surface Reconstruction
Peripheral vascular disease
Spinal Cord injury
Age related Macular Regeneration
Institutional Committee for Stem Cell Research
Heart Surgery Forum; 2007
Journal of American College of Cardiology,2010
Journal of Cardiovascular Magnetic Resonance, 2011
Indian Journal of Nuclear Medicine; 2014
Pediatr Srgu Int. 2011 Cornea ; 2011
IOVS , 2011 World Journal of Retina and Vitreous;2012,5-13