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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Dr. Raka Jain

Dr. Raka Jain

Professor

MSc. (Chemistry), Ph.D. (Medicinal Chemistry), CChem FRSC (U.K).

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Officer-Incharge NDDTC Laboratory

                                            

Field of interest:  Drug Addiction

  1. Drug Analysis (Toxicology)
  2. Neuro-Psychopharmacology (Biochemical, Molecular and preclinical Behavioral studies)
  3. Abuse liability studies of psychotropic drugs
  4. Validity of  drug use reporting and pattern of drug abuse among drug users
  5. Tobacco cessation

 

Total number of Publications till to date: 117Nos.

 

Peer reviewed National & International Journals till date: 100 Nos.

Chapter in Books/report/Manual/monograph till date: 17 Nos.

 

Presentations made at National and International scientific meetings /Conferences/workshops and abstracts published: 83 Nos.

 

Details of publications from year 2004 onwards till to date:

 

  1. Jain, R.  Self-reported Drug Use and Urinalysis Results. Ind. J. Physiol. Pharmacol. 48: 106-110 (2004).
  2. Jain, R. Mukherjee, K., Mohan, D.   Evidence  for a  role  of nitric oxide in nicotine precipitated withdrawals in the rat. Nic. Tob. Res. 6:  873 (2004).
  3. Jain, R.  Mukherjee,  K. , Rajvir, S.  Influence of sweet tasting solutions on opioid withdrawal.  Brain. Res. Bull. 64: 319-322 (2004).
  4. Jain, R., Holtzman, S.G. Caffeine Induces Differential Cross-tolerance to the Amphetamine-like Discrimination Effects of Dopaminergic Drugs. Brain. Res.  Bull. 65: 415-421 (2005).
  5. Prasad, HRY., Khaitan, BK., Ramam, R., Sharma, VK., Pandhi, RK., Agarwal, S.,   Dhawan, A., Jain, R. Diagnostic Clinical Features  of  Pentazocine Induced Ulcers.   Int.  J. Dermato. 44: 910-915 (2005)
  6. Jain, R., Varghese, S.T. Diagnostic usefulness of liver function tests in alcohol and  opoid dependent patients. Addit. Disoder. Their. Treat. 4: 117-120 (2005).
  7. Malhotra, S., Jain, R., Varghese, S.T. Effectiveness and compliance of naltrexone in opioid-dependent patients: A pilot studt from India. Addit. Disoder. Their. Treat. 5: 129-132 (2006).
  8. Jain, R., Tripathi, B.M., Varghese, S.T., Kumar, N., Kumar, M. Can you Trust Self-reports among Injectable Drug users in Clinical Setting?  J. Subs. Use. 11: 431-436 (2006).
  9. Singhal A., Tripathi BM., Pal HR, Jena R., Jain, R. Subjective effects of additional doses of buprenorphine in patients on buprenorphine maintenance. Addict Behav. 32: 320-331 (2007).

10. Jain, R., Mukherjee, K., Mohan, D. Effects of nitric oxide synthase inhibitors in attenuating the nicotine withdrawals in rats. Pharmacol. Biochem. Behav. 88: 473-480 (2008).

11. Jain, R., Mukherjee, K., Balhara, Y.P.S.  The Role of NMDA Receptor Antagonists in Nicotine Tolerance, Sensitization, and Physical Dependence: A Preclinical Review. Yonsei Med J 49: 175-188 (2008).

12. De, Shantanu., Jain, R., Ray R., Dhawan, A., Varghese, S.T. Assessment of Differential Doses of Buprenorphine for long Term Pharmacotherapy among opiate  Dependent Subjects. Ind. J. Physiol. Pharmacol. 52:   53-63 (2008).

13. Jain, R. Book Review entitled “WHO expert Committee on Drug Dependence, Thirty-fourth Report”. Indian J Med Res  127: 96-97 (2008).

14. Singhal A, Tripathi BM, Pal HR, Jena R, Jain R.  Effect of buprenorphine on psychomotor functions in patients on buprenorphine maintenance. Journal of opioid Management , 4: 41-47 (2008).

15. Jain, R., Balhara, Y.P.S.  Neurobiology of Cannabis Addiction. Ind. J. Physiol. Pharmacol. 52: 217-232 (2008).

16. Zolkowska, D., Jain, R.,  Rothman, RB., Partilla, J.S., Roth, BL., Setola, V., Prisinzano, T.E., Baumann, M.H. Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil. J. Pharmacol.Exp. Ther. 329: 738-746 (2009).

31. Jain, R., Balhara, Y.P.S.  Impact of alcohol and substance abuse on adolescent brain: a preclinical perspective. Ind. J. Physiol. Pharmacol. 54: 213-234 (2010).

32.Pattanayak, R.D.,  Jain, R., Ray, R. Jain, R. Validity of self-reported benzodiazepine use among consecutive treatment seekers at a tertiary care drug dependence centre. Ind. J. Physiol. Pharmacol. . 54: 337-243 (2010).

33.Balhara,Y.P.S., Jain , R. Dhawan, A., Mehta, M.  Assessment Of Abuse Liability Of  Pheniramine Among Opioid Dependent Human Subjects.  JSU 2011, 16: 484-495 (doi:10.3109/14659891.2010.513753)(2011).

34.Jain, K.D., Jain, R., Dhawan, A. Double-Blind, Double-Dummy Randomized Controlled Study of Memantine versus Buprenorphine in Naloxone Precipitated Acute Withdrawal in Heroin Addicts. J Opioid Manag  7:11-20  (2011).

35.Jain, R., Pattanayak, R.D. Pattern of consecutive urinalysis results for patients on take-home buprenorphine-naloxone in India: Do patients really take it at home?      JSU, 17: 230-234(doi:10.3109/14659891.2011.555055),(2012).

36.Jain, R., Pattanayak, R.D. Pattern of consecutive urinalysis results for opioid dependent patients on dextropropoxyphene: Do patients comply? Addict Disord. Their Treatment .10: 188-190, doi: 10.1097/ADT.0b013e3182133b76.(2011).

37.Balhara,Y.P.S., Jain , R. Sundar, S., Sagar,R. A comparative study of reliability of self-report of tobacco use among patients with bipolar and somatoform disorder. J Pharmacol Pharmacother. 2: 174-178, IP: 122.161.215.210.doi: 10.4103/0976-500X.83282 ,PMID: 21897711, (2011).

38. Pattanayak, R.D. Sagar,R., Jain, R. Perceived health risks, attitudes and readiness to quit tobacco among Bipolar disorder patients in regular contact with mental health services: An exploratory study from India. . J Ment  Health. 21: 83-90 (2012).

39.Quraishi, R.,  Jain, R.,   Pattanayak, R.D.      Laboratory  Profile  of Current Injecting Drug   Users   Seeking  Treatment  at  a  Tertiary Care Center in India: What do the       Regular  Blood  Tests  and  HIV  Screening Say?  Addict Disord. Their Treatment. doi:  10.1097/ADT.0b013e3182404043. December7, 2011.

40. Srinivas, T.R, Jain R., Tripathi B.M., Pal, H.P., Balhara, Y.P.S.  Extent of use and concordance of self report and urinalysis of benzodiazepine abuse: a comparative analysis in alcohol and opioid dependent individuals. Addict Disord. Their Treatment 11: 26-35 (2011).

41.Jain, R., Balhara, Y.P.S., Jhanjee,S., Sethi, H.Concordance between urinary cotinine levels and self-reported tobacco use among drug dependents: a pilot study. Subs Abuse. 33:  99-102, doi:10.1080/08897077.2011.630947 (2012).

42.Balhara, Y.P.S., Jain, R. Urinalysis based comparative evaluation of pattern of use of dextropropoxyphene and buprenorphine among opioid dependent subjects. J Opioid Manag .8: 45-49 (2012).

43. Pattanayak, R.D.,Jain, R.,  Sagar, R. Reliability of self-reported tobacco use in bipolar disorder: An exploratory study of euthymic patients visiting a tertiary care hospital  in India. Int J Psychiatry Med.  43: 153-163  (2012).

44. Jain, R., Quraishi, R., Majumder, P.,   Pattanayak, R.D. Comparison of self-report and biological measures for alcohol, tobacco and illicit drug use in consecutive alcohol dependent patients visiting a tertiary care centre. JSU., April 19, 1-9 , (doi:10.3109/14659891.2012.674625)  (2012).

45. Balhara, Y.P.S., Jain, R.    A urinalysis-based    study    of   buprenorphine  and non-prescription opioid use among patients on buprenorphine maintenance.    J Pharmaco  Pharmacother. 3: 15–19. doi:  10.4103/0976-500X.92496. (2012).

46.Balhara, Y.P.S., Jain, R. A urinalysis based comparative study of compliance on     Buprenorphine and Buprenorphine/Naloxone combination used as Opioid    Substitution Therapy. Innov Clin Neurosci. 9: 24-29 (2012).

47. Jain,R. Ensuring balance in national policies on controlled substances: Guidance for availability and accessibility of controlled medicines.( Book Review, WHO, Geneva, 2011). Indian J Med Res 136:313-316 (2012).   

48. Balhara, Y.P.S., Jain, R. Sagar,R.,  Sundar, S.    Use  of  cotinine urinalysis to verify

Self- reported tobacco use among male psychiatric out- patients. Lung India, 29:17- 220 (2012).

49. Balhara, Y.P.S., Jain, R. A Receiver Operated Curve (ROC) based evaluation of change in sensitivity and specificity of cotinine urinalysis for detecting active tobacco  use. J Cancer Res Ther.;9: 84-89 (2013) doi: 10.4103/0973-1482.110384.

50. Balhara,Y.P.S.  Jain, R. A urinalysis based study of buprenorphine and non-prescription opioid use among patients on buprenorphine  maintenance. J. Pharmacol.Pharmacother. 3: 15–19. doi:  10.4103/0976-500X.92496. (2012).IP: 122.151.134.137. (2012).

51. Jain, R. Ensuring balance in national policies on controlled substances: Guidance for availability and accessibility of controlled medicines (Book Review, WHO, Geneva, 2011). Indian J Med Res 136:314-316 (2012).   

52. Quraishi, R.,  Jain, R., Anish , P.K. Naltrexone level and biochemical profile of opiate dependent patients on naltrexone maintenance programme: A pilot study. Addict Disord. Their Treatment  (ahead of print)10.1097/ADT.0b013e31827a1ede (2013)

53. Chawla, J.M., Pal, H., Lal, R., Jain, R., Schooler N. Comparison of efficacy between Buprenorphine and Tramadol in the detoxification of opioid (heroin) dependent subjects. J Opioid Manag.  9: 43-50  (2013).

54. Quraishi R, Jain R.,  Ambekar, A . The use of dried blood spot samples in screening drugs of abuse.  Pharmacology & Pharmacy  4: 152-159 (2013).

55. Quraishi, R., Pattanayak, R.D.,  Jain, R.,  Dhawan A.  A   descriptive study of clinical, hematological and biochemical parameters of inhalant users seeking treatment at a tertiary care centre in India. Indian J Psychol Med  35: 174-179 (2013). doi: 10.4103/0253-7176.116249.

56. Jain R. Jhanjee, S., Jain, V.,  Gupta, T.,  Mittal, S.,  Goelz, P.,  Wileyto, P., Schnoll, R.A. A Double-Blind Placebo-Controlled Randomized Trial of Varenicline for Smokeless Tobacco Dependence in India . Nicotine Tob. Res.  16: 50-57 (2014)  doi: 10.1093/ntr/ntt115.

57. Quraishi, R., Jain  R., Chatterjee, B.  Laboratory profile of cannabis dependent and concurrent other substance users seeking treatment at a tertiary care centre in India. Int J High Risk Behav Addict 2: 107-11,(2013) doi: 10.5812/ijhrba.10993.

58. Jain R.,  Gupta, T.,  Majumder, P.  Pharmacological intervention of Nicotine  dependence.   Biomed Res Int. 2013;2013:278392. doi: 10.1155/2013/278392. Epub 2013 Dec 29.PMID:24490153

59. Quraishi, R., Jain, R. ANKK1/TaqA1 Genotyping from Dried Blood stored on Filter                    Paper Among Alcohol & Nicotine Dependent Subjects. British Biomedical Bulletin 2: 263-266 (2014).

60. Jain, R.  Book Review entitled “WHO expert Committee on Drug Dependence, Thirty-fifth Report”  WHO, Geneva, 2012. Indian J Med Res. 139: 789-791(2014).   

61.Chatterjee, B.,Quraishi, R., Jain, R. Socio-demographic and drug use  characteristics of treatment-seeking cannabis users at a tertiary care centre in India. Addict Disord. Their Treatment  13: 110-115 (2014)doi: 10.1097/ADT.0b013e31828bf7f2.

62.Balhara, Y.P.S., Jain, R. Cannabis use among opioid-dependent individuals on    opioid substitution. J. Pharmacol.Pharmacother.  5: 203-205 (2014).

63.Bhad, R., Mehta, M., Dhawan, A.,  Jain, R. Neurocognitive assessment of adolescent inhalant users in treatment setting of India. Indian J Psychiatry 56: SupplS1: 19-62. (2014).

64. Jain, R., Raghav, R.,Roy, T.S.,  Dhawan, A. Kumar ,P. Attenuation of opiate withdrawals by Co-administration of nalbuphine in opiate dependent rats. Alcohol and Alcoholism, 49: Suppl.1, i48 (2014).

65. Jhanjee, S., Pant, S., Girdhar,R., Gunasekhar,R., Jain, R., Sethi, H.  In-Prison outcomes of buprenorphine maintenance for prisoners: Results from a pilot intervention in Tihar prisons, India. Alcohol and Alcoholism, 49: Suppl.1, i64. (2014).

66. Jhanjee, S., Dayal., P., Shankar, R., Jain, R. Opportunities and challenges for youth Tobacco Cessation.  Indian J Soc. Psychiatry, 30: A10 (2014).

67. Bhad R., Jain, R., Dhawan, A., Mehta, M. Biochemical Assessment of Inhalant Use among Adolescents: A Pilot Study from Tertiary De-Addiction Center of India. J Subst Abuse Alcohol 2: 1021-1024 (2014).

68. Jain R. An efficient   screening method for detection of toluene -based inhalant abuse  in urine by Gas Chromatography-Nitrogen Phosphorous Detector. Addict Disord. Their Treatment 14: 47-52 (2015) doi: 10.1097/ADT.0b013e31829bb3d0

69. Jhanjee, S., Suruchi, P., Girdhar, N.,  Sethi, H., Gunasekaran, Rengaswamy., Jain, R.,  Sarangi, J. Opioid Substitution Treatment in Tihar prisons, India: Process of implementation. Int J Drug Policy. 26:890-1(2015) doi: 10.1016/j.drugpo.2015.05.016. Epub 2015 PMID:26123894.

70. Dhawan A., Chopra, A., Jain, R., Yadav, D., Vedamurthachar. Effectiveness of yogic breathing intervention on quality of life of opioid dependent users. Int J Yoga. 8:144-147 (2015). doi: 10.4103/0973-6131.154075. PMID:26170596

71. Jain, R., Jhanjee, S.,  Jain, V.,  Gupta, T., Mittal, S.,  Chauhan, P., Raghav, R., Goelz,  P., Schnoll, R.A. Biochemical Validation of Self-Reported Smokeless Tobacco    abstinence   among Smokeless Tobacco Users: Results from A Clinical Trial of       Varenicline in India.  J Psychoactive Drugs. 47:331-335(2015) doi: 10.1080/02791072.2015.1073412. PMID:26317285

72. Jhanjee, S. Jain, R.,   Jain, V.,   Gupta, T.,  Mittal, S.,   Goelz,  P.,  Schnoll, R.      Evaluating craving withdrawal and affect as correlates of cessation in a  randomized double- blind placebo-controlled clinical trial of Varenicline for smokeless tobacco   dependence in India. J Psychoactive Drugs 47: 325-3309(2015) doi: 10.1080/02791072.2015.1075092. PMID:26317176

73.Mandal, P., Jain, R., Jhanjee, S.  Psychological barriers to tobacco cessation in Indian buprenorphine-naloxone maintained patients -A pilot study. Indian J Psychol Med. 37:299-304 (2015) doi: 10.4103/0253-7176.162944. PMID: 26664077

74. Jain, R., Verma, A. Laboratory approach for diagnosis of toluene-based inhalant  abuse in a clinical setting. J Pharm Bioallied Sci. 8:18-22 (2016) doi: 10.4103/0975-7406.164293. 

75.Qureshi, R., Jain, R., Ambekar, A., Mishra, A.K. Association of ANKK I polymorphism with co-morbid alcohol and nicotine dependence: A pilot study from a tertiary care treatment center in North India. Indian J Med Res, (Accepted for Publication).

76. Bhad, R., Jain, R., Dhawan, A., Mehta, M.  Why do young people sniff? An exploratory study of adolescent inhalant abuse from north India . J Subst Use 2016, 00(00): 1–3 . DOI: 10.3109/14659891.2015.1082158.

77. Verma, A., Jain, R. , Dhawan, A., Lakshmy, R. Assessment of Lipid Peroxidation Biomarker Malondi-aldehyde Among Adolescent Inhalant Users. Ind. J. Pharmacol. 2015 :  47; S145.

78. Raghav, R., Jain, R., Roy, T.S., Dhawan, A., Kumar, P. Effect of Acute and Chronic Administration of Nalbuphine on Motor Activity in Opiate Dependent. Ind. J. Pharmacol.  2015;  47:| S66.

79. Das, M., Jain, R., Dhawan, A., Kaur A. Assessment of abuse liability of Tramadol among experienced drug users: Double-blind crossover randomized controlled trial. J Opioid Manag. 2016; 12:421-430. doi: 10.5055/jom.2016.0361.

80. Jain, R., Quraishi, R., Verma, A. Evaluation of Dried Urine Spot Method to Screen Cotinine among Tobacco Dependents: An Exploratory study. Indian J Psychol Med. (in press ).

 

Chapter in Books

  1. Ray, Jain, R.  R. Mongia, M. and Kumar, R. Substance Abuse in Young People: Biological Considerations.  In Mental Disorders in Children and Adolescents: Need and Strategies for Intervention, CBS Publishers, New Delhi, pp 82-87 (2005).
  2. Jain, R. Role of Laboratory Services In: Lal R (Ed). Substance Abuse Disorder:   Manual for Physicians, National Drug Dependence Treatment Centre, All India, Institute of Medical Sciences, New Delhi, 2005: pp127-137.
  3. Jain, R. Role of Laboratory Services in Management of Substance Use Disorder In: Lal R., Gupta S.  (Eds). Substance Abuse Disorder:   Manual for Nurses, National Drug  Dependence Treatment Centre, All India, Institute of Medical Sciences, New Delhi, 2007: 169-181.
  4. Jain, R. Role of Laboratory Services in Management of Substance Use Disorder In:  Lal R., Gupta S.  (Eds). Substance Abuse Disorder:   Manual for Nurses, National Drug  Dependence Treatment Centre, All India, Institute of Medical Sciences, New Delhi, 2007: 169-181. (reprinted , 2013).
  5. Jain, R. Role of Laboratory Services In: Lal R (Ed). Substance Abuse Disorder:   Manual for Physicians, National Drug Dependence Treatment Centre, All India, Institute of Medical Sciences, New Delhi, 2nd Ed. 2013: pp127-137.

6. Quraishi, R., Jain, R., Ambekar, A. Dried Blood Spots for Testing Drugs, In: Dried Blood Spots for Testing Drugs of Abuse, In: Detection of Drug Misuse : Biomarkers, Analytical Advances and Interpretation  , Wolff, K  (ed) RSC , UK , (in press)

 

Editor: and Author

 

  1. Jain, R., and Mukherjee, K. Biological Theories of Tobacco abuse.  In: Proceedings of  the workshop on assessment of tobacco as a gateway substance and information available on evidence relating to tobacco, alcohol and other forms of substance abuse (Eds. Dhawan A, Jain, R., Kumar, N.), New Delhi, India: Centre for Behavioral Sciences, AIIMS, sponsored by WHO India, & MOH & FW, GOI, pp. 33-38 (2004).  

Report

  1. Jhanjee, S., Jain, R., Sethi, H. Rolling out of Opioid Substitution Treatment (OST) in Tihar Prisons, India: Scientific Report, A collaborative project of UNODC- ROSA, AIIMS & Tihar Prisons, Published by United Nations Office on Drugs and Crime, , Regional Office for South Asia,(2013).
  2. Dhawan, A., Rao, R., Ambekar, A., Chopra, A., Jain, R., Yadav, D., Ray, R. Methadone Maintenance Treatment in India: A feasibility and effectiveness Report. UNODC (ROSA) and NDDTC (AIIMS), New Delhi, India,  Published by United Nations Office on Drugs and Crime, Regional Office for South Asia. (2014).
  3. Ambekar, A., Rao,R.,  Varshney,M., R., Prashanth., Dhawan, A.,  Jain, R., Ray, R., Bhola, s., Gupta, N., Chopra, A., Sethi, H. Post Marketing Surveillance of Methadone in India,  National Drug  Dependence  Treatment  Centre,  All India  Institute  of  Medical Sciences, New Delhi. (2014).

 

Monograph

  1. Dhawan, A., Jain , R., Chopra, A.  Opioid Substitution- Buprenorphine in India, New Delhi: UNODC, 2010. 

Presentations made at scientific meetings/ conferences/ workshops and Abstract Published from yr. 2000 onwards till to date:

 

1.Assessment of Drug Use: Comparison of Reported Drug Use and Urinalysis. Jain, R.  B.  M.  Tripathi,  (Abstract)  in  Annual  National  Conference  of  Indian Psychiatric Society, Cochin, (20-23rd Jan. 2000).

2.Buprenorphine: Pharmacology, Pharmacokinetics and Theurapeutic Potential, Jain, R. (invited talk)   in  National  workshop  on Treatment of opiate Dependence Disorder  with  Special  Focus  on Maintenance Programme, De-addiction Centre, AIIMS, New Delhi, (17-18th April, 2000).

3.Role of Mass Spectrometry in Detection of Drugs of Abuse, Jain, R.  (invited talk) in 9th ISMAS Workshop on Mass Spectrometry, Goa (12-16th Dec. 2000).

4.Role of Dopaminergic Drugs in Nicotine tolerance: A Pre-clinical Study, Jain, R.  S. Varma,  D. Mohan,  (Abstract)  in  Annual  Conference  of  Indian Psychiatric Society, Pune, (9-12th, Jan, 2001).

5.Assessment of Tolerance and Dependence: Pre-clinical Aspect, Jain, R.  (invited talk) in Annual Conference of Neuro-science, Lucknow (29-30th Jan. 2001).

6.Tolerance and Dependence: Preclinical Aspect, Jain, R.  (invited talk) in AIIMS - NIAAA Workshop on Substance Use Disorder, Drug Dependence Treatment Centre, AIIMS, New Delhi (6th March, 2001).

7.Enhanced Sensitivity to Behavioral Effects Of Naloxone. Jain, R.  R.Ray in 6th  NIDA / INVEST Meeting on Building International Research on Drug Abuse: Children and Youth at Risk at Scottsdale, Arizona, USA (June, 14-16th, 2001).

8.Effect  of  Selective  Dopaminergic Drugs in Nicotine Tolerant Rats. Jain, R., Varma, S. Mohan D. Jain, R.   in College on Problems of Drug Dependence, 63rd Annual Scientific Meeting, Scottsdale, Arizona, USA (June, 16-21st, 2001).

9.Evidence for an Involvement of D2 Dopamine Receptor in Mediating Nicotine Tolerance in Rats  Jain, R.  S. Varma, D. Mohan in Annual Meeting of Society for   Research   &  Tobacco  (SRNT) at Savannah, Georgia, USA, dated (February 20 – 23, 2002). 

10.Clinical Utility of Drug Abuse Testing  : Self Report Vs. Urinalysis. Jain, R.  in 9th Asian Pacific Congress of Clinical Biochemistry, New Delhi. dated (March 9-14th,  2002).

11.A Pilot Study on the Consistency of Self-Reported Drug Use and Urinalysis. Jain, R.  in College on Problems of Drug Dependence, 64th Annual Scientific Meeting, Quebec City, Canada (June, 8-13, 2002).

12.Comparison of Patient self-Reports and Urinalysis in the Community outreach Clinic, Jain, R.   B. S. Chavanin 7th  NIDA / INVEST Meeting on Building International Research on Drug Abuse: Treatment Innovations,   Quebec City, Canada (June, 13-15th, 2002).

13.Biological Theories of Tobacco Abuse , Jain, R.  in workshop on Assessment of Tobacco as a Gateway substance and Information on evidence relating to Tobacco, Alcohol and other Forms of Substance Abuse, All India Institute of medical Sciences, New Delhi (Sept, 4-5th, 2002).

14.Effects of Dopaminergic Drugs in Nicotine Tolerant Rats, Jain, R.  S. Varma, D.  Mohan, in 2nd World Assembly on Tobacco Counters Health, New Delhi, India (Sept., 29th- 3rd Oct 2002).

15.Self-Reported Drug use Among Injectable Drug Users, Jain, R.  B. M. Tripathi, S. Singh, N. Kumar, M. Kumar in  2nd International Conference On HIV and Substance Abuse , HOPE 2002 , Mumbai, India (Dec 1-3rd, 2002).

16.Role of liver Function Tests in Assessment of Alcoholics and Opioid Addicts. Jain, R.  R. Singhin 2003 NIDA International Forum, Building International Research: Emerging Trends and patterns in Drug Abuse Around the World.  Miami, Florida (June, 13-19th, 2003).

17.Moderate Drinking-Preclinical Aspects. Jain, R.  (invited talk)In National Workshop on Responsible Drinking- Review of Evidence and Formulation  of Recommendations, National Drug Dependence Treatment Centre, AIIMS, New Delhi (Sept, 1-2nd, 2003).  

18.Evidence for a Role of Nitric Oxide in Nicotine Precipitated Withdrawal in the Rat. Jain, R.  K. Mukherjee, D. Mohan in Fifth European Conference of the Society for Research on Nicotine and Tobacco at Padua, Italy (Nov, 18- 24th, 2003).

19.Tobacco and Nicotine Related Studies at National Drug Dependence Treatment Centre, AIIMS: An overview.  Jain, R.  in Fifth European Conference of the Society for Research on Nicotine and Tobacco at Padua, Italy (Nov, 18- 24th, 2003).

20.Influence of Sweet tasting solution in morphine withdrawal - A pilot study Jain, R.  K. Mukherjee., In XXXVI Annual Conference of  Indian  Pharmacological Society, New Delhi ( Dec, 5-7th, 2003).

21.Effect of Nitric Oxide Synthase Inhibitors in Nicotine Precipitated Withdrawal Rats. Jain, R.  K. Mukherjee.,In World Assembly on Tobacco Counters Health, New Delhi (March, 7-11th, 2004).

22.Role of sweet tasting solution in opiate withdrawal. Jain, R.  K. Mukherjee., In Satellite Meeting of 2004 NIDA international Forum: Progress through Collaboration, San Juan, Puerto Rico (June 11-14th, 2004).

23.Effects of the NMDA receptor antagonists (Ketamine) to the operant decrement produced by naloxone in morphine - treated rat. Jain, R.  In 66th Annual Scientific Meeting of College on Problem of Drug dependence, San Juan, Puerto Rico (June 12- 17th, 2004).

24.Effect of nitric oxide synthase inhibitors in nicotine dependent rats Society for Research on Nicotine and Tobacco’s:  Jain, R. . In 11th Annual Meeting held jointly with the 7th SRNT European Conference’ (20-23 rd March, 2005) at Prague ‘Czech Republic’.

25.Drunken Driving. Jain, R.  (invited talk). In. Workshop on Road Rage: A study of Aggressive behavior and intervention strategies Deptt. of Psychiatry, AIIMS, New Delhi.  (May 4rth, 2005).

26.Role of laboratory in Primary Health Care.  Jain, R.  (invited talk). In. Workshop on Managing Alcohol Abuse in Primary Care Setting: A study of Aggressive behavior and intervention strategies, National Drug Dependence Treatment Centre, AIIMS, New Delhi.   (June 17th-18th, 2005).

27.Comparison of the effects of nitric oxide synthase inhibitors in nicotine dependent rats.  Jain, R.  K. Mukherjee, D. Mohan. In Satellite meeting of 2005 NIDA International Forum: Linking Drug Abuse and HIV/AIDS in conjuction with 67-th Annual Scientific meeting of College on Problem of Drug Dependence (CPDD)  (June17th-23rd, 2005), Orlando, Florida, USA.   

28.Can you Trust Self-reports among Injectable Drug users in Clinical Setting? Jain, R., Tripathi, B.M., Varghese, S.T., Kumar, N., Kumar. In 6th NIDA/INVEST Meeting on International Trends and Needs in Drug Abuse Research at Scottsdale, Arizona, USA (June, 16-19th, 2006). Scottsdale, Arizona, USA.  

29.Patterns of Drug Use: Role of Urine Testing. Jain, R. Sethi Hem. In International Symposium on Forensic Science at Amity Institute of Advance  Forensic Science Research and Training (1-4 August. 2007) Noida, UP, India.

30.Concordance between Urinary cotinine levels and self-reported tobacco use among drug dependents: A Pilot study.  Jain, R., Balhara, Y.P.S., Jhanjee S., Sethi, H.S. In 5th World Assembly on Tobacco Counters Health, New Delhi (Dec.2-5th, 2007).

31.Comparison of Self-Report of Tobacco Use and Urinary Cotinine Levels among Drug Dependents: A Pilot Study. Jain, R., Balhara, Y.P.S., Jhanjee S., Sethi, H.S.In 14th Annual Meeting February of Society for Research on Nicotine and Tobacco at Portland, Oregon, USA (27th Feb - 1st March, 2008).

32.Role of urine testing in evaluation of illicit drug use and ensuring compliance in opioid dependent subjects maintained on sublingual buprenorphine substitution therapy. Jain, R., Balhara, Y.P.S. In 10th Annual Meeting for the International Society of Addiction Medicine, Cape Town, South Africa (16-20th Nov, 2008).

33.Compliance and detection of illicit drug use among opioid dependent subjects maintained on sublingual buprenorphine substitution therapy. Jain, R., Balhara, Y.P.S. In International Conference of Translation Pharmacology and 41st Annual Conference of Indian Pharmacological Society, (18-20th Dec. 2008), AIIMS, New Delhi.

34.Role of Nitric Oxide Synthase Inhibitors in Nicotine Dependent Rats. Jain, R., Mukherjee, K., Mohan D. In:  National Symposium on Emerging Trends in Nitric Oxide Research,   (12th Jan, 2009), Vallabhai Patel Chest Institute, University of Delhi.

35.Participated in “Regional Advocacy Workshop on “Tobacco Control Law & Measures” scheduled on 16-17 Jan 2009 at Chandigarh in collaboration with MOH & FW, GOI.  

36.Participated in “14th World Conference on Tobacco or Health” on 8-12th March 2009 at the National Centre for Performing Arts Mumbai, India. 

37.Effects of Nitric Oxide Synthase Inhibitor to the Operant Decrement produced by Naloxone in Morphine Dependent Rats. Jain, R., In: 2nd Annual International Drug Abuse Research Society (IDARS) & International Society  for Neurochemistry Satellite Meeting  In Association with Korean Society  for Drug Abuse Research  (17-21st August, 2009),  Grand Hyatt Hotel, Seoul, S. Korea.

38.Tobacco use: Relationship between self-report and urinary cotinine. Jain, R., Balhara, Y.P.S., Jhanjee, S., Sethi, H. In: Silver Jubilee Year Conference of the Indian Association for Social Psychiatry (16th-17th Nov.) 2009 at Lucknow.

39.Neurobiological basis of nicotine addiction: An update (invited talk). Jain, R., Chatterjee, B., In: XXVII Annual Conference of Indian Academy of Neurosciences at Jaipur (18-20th Dec. 2009).

40.Role of nitric oxide synthase inhibitors to the operant decrement produced by naloxone in morphine treated rats. Jain, R., In: “2010 NIDA International forum: Drug Abuse Research Policy and the Public Good & CPDD 72 Annual Scientist Meeting, at The Fairmont Scottsdale, Scottsdale, Arizona, USA (11-17th June, 2010).

41.Compliance of Prescribed Benzodiazepines in Alcohol and Opioid Dependent Subjects Based on Urinalysis.   Jain, R., In: 10th Indo-Pacific Congress on Legal Medicine and Forensic Science at Amity University, UP (25-30th. Oct. 2010).

42.Drug Abuse Testing in Substance Abuse Treatment Program: AIIMS NDDTC Experience. Jain, R., “2nd International Conference on Medical Negligence in Medical Practice and on Recent Advances in Forensic Sciences, Medicine Toxicology at Hotel Riveriera De Goa, at Goa (20-21st Feb., 2011).

43.Pattern of urinalysis results for patients prescribed with dextropropoxyphene in opioid dependent  subjects: Do patients really  comply? Jain, R., Pattanayak, R.D. In “2011 NIDA International forum: Building International Collaborative Research on Drug Abuse and CPDD 73rd Annual Scientific Meeting  from June 17th to 23rd, 2011 at The Westin Diplomat Hollywood, Florida, USA (17th - 23rd June.,  2011).

44.Participated in Refresher Training on Opioid Substitution Treatment in Tihar Prison  on  11th Nov. 2011.

45.Delivered a invited talk on “Role of Laboratory Services in Substance Abuse Treatment Programme” to training course Participants of CRCL, Govt. of India,   New Delhi (15th Nov. 2011).

46.Comparison of  self-report and biological measures for alcohol, tobacco and illicit drug use in alcohol dependent patients  Jain, R.,  Quraishi, R., Majumder, P., Pattanayak, R.D. In “3rd International Conference on  Legal Medicine, Medical  Negligence in Medical Practice and on  Current Trends in Forensic Sciences, Medicine Toxicology  at  Hotel Ramada  Jaipur  (3rd - 5th Feb. 2012).

 

47.Delivered a invited talk on “Role of Laboratory Services in Drug Dependence Treatment Programme” on Forensic Science Day,  at Amity University, UP (23rd March, 2012).

48.Participated and attended in training programme on “Medical Laboratory Quality Management System And Internal Audit as per IS-ISO 15189” conducted by National Institute of Training for Standardization Bureau of Indian Standards at AIIMS, New Delhi (8th -11th August, 2012).

49.Laboratory detection of toluene –based inhalant abuse in urine. Jain, R., In “4th  International Conference on Legal Medicine, Medical Negligence and Litigation in Medical Practice  4th International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology   at  Uday Samudra Hotel, Kovalum, Thiruvananthapuram, Kerala.  (25th- 27th Jan. 2013).

50.A randomized double-blind placebo-controlled clinical trial of varenicline for smokeless tobacco dependence in India.  Jain, R.,  Jhanjee, S., Jain, V.,  Gupta, T.,  Mittal, S.,  Goelz, P.,  Schnoll, R., In 2013 SRNT (Society for Research on Nicotine and Tobacco) 19th Annual International Meeting, Westin Boston Waterfront Hotel Boston, Massachusetts, USA. (13th-16th March, 2013).

51.Effect of nitric oxide synthase inhibitor,  nitro-l-arginine (L-NNA),  on sensitization to the operant decrement produced by naloxone in morphine treated rats Jain, R. In 2013 NIDA International forum: Building International Collaborative Research on Drug Abuse and  CPDD 75th Annual Scientific Meeting,  at The  Hilton Bayfront Hotel, San Diego, CA, USA.  (14th - 20th June, 2013).  

52.An Efficient Method for Detection of Opiate in Dried Urine Specimens among Opioid Users. Jain, R.,  Quraishi R,  Verma A,  Ambekar A. In 11th Indo Pacific Association of Law, Medicine and Science Congress 2013 (INPALMS 2013), at Shangri-La Hotel, Malaysia, Kuala Lumpur (5th–10th Oct, 2013).

53.Biochemical Validation of Self-reported Smokeless Tobacco Abstinence Among Smokeless Tobacco Users: Results from a Clinical trial of Varenicline in India. Jain, R.,  Jhanjee, S., Jain, V.,  Gupta, T.,  Mittal, S.,  Goelz, P.,  Schnoll, R., In 2014 SRNT (Society for Research on Nicotine and Tobacco) 20th Annual Meeting  at Sheraton Seattle Hotel Seattle, Washington, USA (Feb 5-8 th 2014).

54.Evaluating Craving, Withdrawal and affect as Mediators of Tobacco Cessation in a Randomized Double-Blind Placebo-Controlled Clinical Trial of Varenicline for Smokeless Tobacco Dependence In India.Jhanjee, S., Jain, R.,  Jain, V.,  Gupta, T.,  Mittal, S.,  Goelz, P.,  Schnoll, R., In 2014 SRNT (Society for Research on Nicotine and Tobacco) 20th Annual Meeting  at Sheraton Seattle Hotel Seattle, Washington, USA (Feb 5-8 th 2014).

55.Attenuation of opiate withdrawals by Co-administration of Nalbuphine in Opiate Dependent Rats. Jain, R., Raghav, R.,Roy, T.S.,  Dhawan, A. Kumar ,P., In  16th International Society of Addiction Society (ISAM) Annual Meeting at Pacifico Yokohama Conference Center, Yokohama, Japan (Oct. 2nd- 6th2014).

56.Role of Biomarkers for Youth  tobacco Cessation: Recent advances, Jain, R.,  In Symposium  entitled “Opportunities and challenges for youth Tobacco” Cessation (Jhanjee, S., Dayal., P., Shankar, R., Jain, R),   National Conference of Indian Association for Social Psychiatry  (NCIASP 2014)  at JSS Medical JSS College hospital, JSS University, Mysore  (Nov.21rd -23rd 2014).

57.Urinalysis based evaluation of pattern of drug use among substance users seeking treatment   at a tertiary care De- addiction Centre of North India. Jain, R. In IAMLE-2015, 6th  International Conference on Legal Medicine, Medical Negligence and Litigation in Medical Practice and 6th International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology at  Hotel Clarks, Khajuraho, Madhya Pradesh  ( Feb. 26th – 28th 2015).

58.Evaluation  of Dried Urine  Spot Method for  Detection of Cotinine among Tobacco Users. Jain, R., Quraishi, R.,Verma, A.  In 2015 NIDA International forum: Building International Collaborative Research on Drug Abuse at Arizona Biltmore Hotel, Phoenix, Arizona, USA.  (12th - 15th June, 2015).

59.Effect of Nalbuphine on Plasma corticosterone levels and opiate withdrawal Raghav, R., Jain, R., Roy, T.S., Dhawan, A., Kumar, P.  In 2015 NIDA International forum: Building International Collaborative Research on Drug Abuse at Arizona Biltmore Hotel, Phoenix, Arizona, USA.  (12th - 15th June, 2015).

60.Effect of Nalbuphine on motor activity and plasma corticosterone levels in opiate dependent rats, Jain, R., Raghav, R., Roy, T.S., Dhawan, A., Kumar, P.  In ISAM  Dundee 2015 Congress, 17th International Society of Addiction Medicine  (ISAM) Congress,  Dundee, Scotland,( October 5th -8th, 2015).

61.Evaluation of Dried Urine Spot Method for Detection of Benzodiazepines among Substance Users”.  Jain, R. , Quraishi, R., Ambekar, A., Verma, A.,   Gupta, P. In IAMLE-2016, 7th  International Conference on Legal Medicine, Medical Negligence and Litigation in Medical Practice and 7th International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology at    The Central Court Hotel, Hyderabad, Telangana  (Jan. 29th –31st 2016).

62.Stability of substance use in urine spotted on filter paper at various storage conditions over a 12 weeks period. Jain, R. , Quraishi, R., Ambekar, A., Verma, A.,   Gupta, P. In  12th Indo Pacific Association of Law, Medicine and Science  INPALMS Congress 2016), at The Stones  Hotel, Bali , Indonesia (17th -23rd September, 2016).

63.Current understanding of the neurobiology of the nicotine dependence: the role of NAchRs and dopamine and their treatment implications. In symposium  entitled “Role of non-nicotinic Acetylcholine receptors in nicotine dependence :Implications for smoking cessation treatment”  (Jain, R.,  Chatterjee, B., Mandal, P.) XXXIV Annual Meeting of Indian Academy of Neurosciences, National Brain research  Centre, Manesar, Gurgaon Dist. Haryana (Oct.19th -21st 2016).

64.  Safety of e-cigarettes- evidence from toxicological studies. In symposium entitle “E- Cigarettes Use: Is It An Acceptable Alternative?” (Jhanjee,S., Jain, R.,  Chatterjee, B., Mandal, P.)  22nd World Congress of Social Psychiatry (WASP2016),The Ashoka, New Delhi (30th Nov.- 4th  Dec.2016)

 

Number of Projects:
Funded Research Projects:

Chief Investigator:

  1. Jain, R.,  D. Mohan.  Role of Dopamine in Experimentally Induced Nicotine Tolerant Rats (funded by Council of Scientific and Industrial Research, Govt. Of India, 1997-2001, completed).
  2. Jain, R.,  R. Ray. Blocking of Enhanced Sensitivity to Behavioral Effects of Naloxone Induced by Narcotic Agonists in Rats (funded by All India Institute of Medical Sciences, 1999- 2000, completed).
  3. Jain, R.,  D. Mohan. Role of Nitric Oxide Synthase Inhibitors In Modifying Nicotine Withdrawals in Rats  ( funded by Council of  Scientific and Industrial Research, Govt. Of India, 2001- 2005, completed).
  4. Jain, R. ., Effects of the NMDA Receptor Antagonist (Ketamine) to the Operant Decrement Produced by Naloxone in Morphine-treated Rats (funded by All India Institute of Medical Sciences, 2002- 2003, completed).
  5. Jain, R.,  S. Jhanjee., V. Jain.  R. Schnoll. Efficacy of Varenicline for Smokeless Tobacco Use in India,     Indo-US collaborative Research Project AIIMS and UPENN (University of Pennsylvania) ( funded by National Institute on Drug Abuse,  National Institute of Health (NIH),  R21 DA026404, NIH, USA, 2011-2014,completed, Rs. 69 lakhs).

6.  R. Jain.,  A.  Ambekar,  R.  Quraishi,  Feasibility of transporting urine samples of drug users on filter paper for screening drugs of abuse:   A pilot     exploratory study (funded by Indian Council of Medical Research funded 2012-2014, completed, Rs. 12.5 lakhs).

7.  R. Jain.,  T.S. Roy, A. Dhawan. Effect of nalbuphine on opiate withdrawal in rats: Behavioural, Biochemical and Molecular study ( funded by Indian Council of Medical Research, 2012-2015, completed, Rs. 46 lakhs).

8. R. Jain., S. Jhanjee, A. Jabeen,  “Role of Delphinium denudatum (Jadwar) in a Rat Model of Nicotine Dependence” (funded by Ministry of AYUSH, Dec. 2016, Rs.  29.16 lakhs, approved).

 

 

Co-Investigator:

  1. D. Mohan., Jain, R., H. Pal. Health Status of Workers with Chronic  Opioid Exposure at Govt. Opium and Alkaloid Factory, Ghazipur, U.P., ( funded by Ministry of Finance, Govt. of India, 1998-2001, completed).
  2. D. Mohan., Jain, R.,  H. Pal. Identification and Management of Alcohol Use Related Disorders in Districts Hospital in Goa. ( funded by WHO India, Ministry of Health, Govt. of India,  2002- completed). 
    1. A. Dhawan., Jain, R.,  A. Chopra. To test the effectiveness of Oral Substitution with Buprenorphine and to establish a protocol for Oral Substitution with Buprenorphine. ( funded by UNODC, 2005-2011, completed).
    2. S.  Jhanjee., Jain, R.,  H. Sethi.  Rolling out of Opioid Substitution Treatment (OST) in Tihar prisons, Indi .( funded by UNODC, 2008-2012, completed).
    3. A. Dhawan., Jain, R.,  D. Yadav.   Effectiveness of Yoga in patients of Opiate Dependence ( funded by AYUSH, MOH & FW. GOI, 2009-2011, completed).
    4. A. Dhawan. R. Ray., Jain, R.,  A. Ambekar., D. Yadav.   A. Chopra. Methadone Maintenance Treatment in India: A feasibility and effectiveness study.   ( funded by  UNODC,  2011-2014,completed).
    5. A. Ambekar, R. Ray., R. Jain, A. Dhawan, A. Chopra, H. Sethi. Post Marketing Surveillance of Methadone (funded by M/s Rusan Pharmaceuticals, 2012-2014,completed).
    6. Y.P.S. Balhara., R. Jain. A comparative study of prevalence of metabolic syndrome among patients with Opioid and Alcohol Dependence Syndrome. (funded by AIIMS, New Delhi, 2013 –completed).      

10. G. Shankar, S. Jhanjee., R. Jain., P. Dayal, A. K. Mishra. Cognitive Behavioural based Intervention in Group Setting for Tobacco Cessation in tertiary de-addiction centre in Northern India Approved (funded by ICMR, ongoing, 2015-2016, Funds: 4,37,280/-).

11. R. D.  Pattanayak, S.K. Khandelwal., R. Jain. Response to Lithium prophylaxis among patients with Bipolar Disorder: Relationship with clinical variables and inflammatory cytokine (TNF-α). (funded by AIIMS,  2015- ongoing, Funds: Rs 1,80,000).

 12.S. Sarkar., R. Jain. Serum BDNF levels in patients with opioid dependence during the early withdrawal period: A case control study. (funded by AIIMS,  2015- ongoing, Funds: Rs  3,15,000).

13. R. Quraishi., R.Jain.,  A. Ambekar., R. Rao.  Feasibility of transporting blood/ serum samples on to filter paper to screen for biomarkers of harmful alcohol use among opioid dependent patients on agonist maintenance treatment: a pilot study in community setting.  (funded by AIIMS,  2016- ongoing, Funds: Rs  2,80,000/).

14. S. Sarkar, A. Sharma., R. Jain, Y.P.S. Balhara. Relationship of serotonin pathway polymorphisms with self harm behaviour among patients with opioid dependence. ( DST, accepted).

 

 

Departmental Research Projects:

Chief investigator:

  1. Jain, R.,  R. Ray, B. M Tripathi, C. Singh. Opiate Excretion Profile among Heroin Dependent Subjects (1992-1993, completed).
  2. Jain, R., N. G. Desai, H. P. Jhingan, M. Vaswani,  B. M. Tripathi. Self Validation of Opiate use in Opiate Addicts. (1993-1994, completed).
  3. Jain, R.,  A. Dhawan. Concordance between Self-reported Drug Use and Urinalysis in Opioid Dependent Subject on Maintenance in the Community (1999-2000, completed).
  4. Jain R. A comparative Evaluation of Efficacy of Diazepam and Buprenorphine In Suppression of Opioid Withdrawal Signs in the Rats (1999- 2000, completed).
  5. Jain R. Influence of Sweet Tasting Solutions in Morphine Withdrawal - A pilot study (2003, completed).
  6. Jain R. Role of Sweet tasting Solutions in modifying the Opioid Withdrawals in rats (2004, completed).
  7. Jain R. Effect of Nitric Oxide Synthase Inhibitor to the Operant Decrement Produced by Naloxone In morphine Treated Rats (2004-2006).
  8. Jain R. Effect of Nitric Oxide Synthase Inhibitor 7-NI on Sensitization to the  Operant Decrement Produced by Naloxone in Morphine Treated Rats. (2006- Ongoing).
  9. Jain R.  Jhanjee, S. Balhara, YPS, Sethi H. Validity of self-reported tobacco use among opioid dependent subjects (2007-completed).

10. Jain, R.  Sethi H.  Evaluation of    Abuse of Prescription Drugs Among Opioid Dependent Patients Based On Urinalysis (NDDTC funded, AIIMS, 2007-completed).

11. Jain, R.  Balhara, YPS, Evaluation of illicit drug use in the opioid dependent subjects maintained on sublingual buprenorphine: Role of urine screening (2007-completed).

12. Jain, R.  Balhara YPS, Shamsunder S, Sagar R. Screening of tobacco use among psychiatric disorders: A pilot study based on urinalysis and self-report (2008-completed).

13. Jain R. Effect of Nitric Oxide Synthase Inhibitor L-NNA on Sensitization to the Operant Decrement Produced by Naloxone in Morphine Treated Rats. (2009- Ongoing).

14. Jain, R.  Compliance of Prescribed Benzodiazepines in Alcohol and Opioid Dependent Subjects Based on Urinalysis.   (2010-completed). 

15. Jain, R.  R, Sagar, Raman Deep Pattanayak. Validity of self-reported tobacco use among patients with bipolar disorder visiting the psychiatric disorder (2010-completed). 

16. Jain, R. Balhara YPS, Quraishi, R. Assessment of biochemical and haematological profile of opioid dependent patients receiving Buprenorphine/Buprenorphine –naloxone Combination (2012-ongoing).

17. Jain, R. Balhara YPS, Quraishi, R. Evaluation of compliance in patients receiving naltrexone for long term management of opioid dependence (2012-2014, completed).

18. Jain, R.  Quraishi, R. Estimation of nicotine in urine samples spotted on filter paper in substance users (2013-2014, completed).

19. Jain, R. An efficient screening method for simultaneous detection of  cotinine, pentazocine and pheniramine in urine of substance users by  Gas Chromatography- Nitrogen- Phosphorus Detector (2015- 2016,completed).

20. Jain, R.,   Jhanjee S., Quraishi, R. Effect of smoking on Platelets Monoamine Oxidase B activity levels in Opioid Dependent Patients on Maintenance Treatment: An Exploratory study. (2016-Ongoing)

 

Co-Investigator             

  1. H. Pal, Jain, R.  Investigation and Management of Psychotropic Substance Problems in Primary Care settings, Phase I, Pilot study (Assist, WHO, 1998, completed).
  2. A. Dhawan, Jain R. Concordance between Self-Reported Drug Use and Urinalysis in Out patient Opioid Dependence subjects (1998-1999, completed).
  3. S. Malhotra., Jain R. Current Pattern of Naltrexone Maintenance and Patient Compliance (2003 -2004 completed).
  4. Raman Deep Pattanayak,  R, Sagar, Jain R. Assessment of knowledge, attitude and perceived health risk for tobacco among patients with bipolar disorder (2010- completed).
  5. R Quraishi, R. Jain Association of ANKK I polymorphism and Nicotine Dependence (ND): A Pilot Study (2012-completed).
  6. Balhara YPS., Jain, R., A urinalysis based evaluation of cannabis use among opioid dependent subjects maintained on buprenorphine: A retrospective study (2012-completed).
  7. Quraishi R. Jain R,  Ambekar A.  Comparative evaluation based on clinical and laboratory profile of HIV screened positive and negative treatment seekers from a tertiary care treatment centre: a retrospective chart analysis study. (2014-completed).

 

 

Thesis supervised as MD/ DM/PhD

 

a)   Chief guide for Postgraduate Medical Students M.D. Thesis –Twelve  (Completed) Two(Ongoing)

b)   Co-guide for Postgraduate Medical Students M.D. Thesis- Eleven (Completed) Four (Ongoing)

c)      Co-guide for Postgraduate Medical Students DM Thesis- Three (Ongoing)

d)    Chief guide for  Ph.D Student Thesis-Three (Ongoing)

e)    Co-guide for  Ph.D Student Thesis-One (Completed)

 

Reviewer for Scientific Peer Reviewed Journals

  i)   Indian Journal of Pharmacology  since 1994

  ii)  Indian Journal of Medical Research  since 2006

  iii) Brain Research Bulletin, 2007

  iv) Neuroscience letters, 2005

  v) Nicotine & Tobacco Research  since 2011

 vi) National Medical Journal of India since 2016

 

         Significant Events:

Awards and Honors:

  • Recipient of United Nations Fund for Drug Abuse Control Programme (UNDCP) fellowship and had five months advance training in ‘Analytical’ Methods of Body Fluid Analysis from September, 1990 to January, 1991 at Institute of Legal Medicine, Forensic Toxicology Laboratory University of Padova, Italy.  During this period, was awarded United Nations Fellowship.
  • Recipient of   National Institute on Drug Abuse NIDA INVEST FELLOWSHIP, US Govt. at Deptt. of Pharmacology, School of Medicine, Emory University, Atlanta, Georgia 30322-3090 for a period of 13 months (1996-1997).
  • Was elected as a Fellow of Royal Society of Chemistry, U.K and was awarded  Cchem FRSC (2000).
  • Recipient of National Institute on Drug Abuse (NIDA) international travel awards for presenting research papers in NIDA International conferences, USA (1999-2004, 2006).
  • Recipient of Travel award to attend NIH Stigma and Global Health Conference at Bethesda, Maryland, USA (Sept. 2001).
  • Recipient of Society for   Research & Tobacco (SRNT) Global Network Travel award 2002 and 2003 for presenting research paper..
  • Chaired the session "Glutamate -What's all the Excitement?” session in   College on Problems of Drug Dependence, (CPDD), USA meeting on 15th June, San Juan, Puerto Rico, USA.
  • Appointed as steering committee member of International Drugs of Abuse Research Society (IDARS) in Oct, 2004.
  • Recipient of WHO/NIDA/CPDD  International traveling Fellowship  award  for   participating and presenting paper   in   Satellite meeting of 2005 NIDA International Forum: Linking Drug Abuse and HIV/AIDS in conjuction with 67-th Annual Scientific meeting of College on Problem of Drug Dependence (CPDD)  (June17th-23rd, 2005), Orlando, Florida, USA.      
  • Recipient of  Distinguished International Scientist Collaboration Award (DISCA), National Institute on Drug Abuse, US, Govt. USA for the year 2006 from (1/6/06-31/8/06). at 5500 Nathan Shock Drive, John Hopkins Bayview Campus, Baltimore, MD, 22124, USA.
  • Recipient of NIDA International Travel Award for presenting papers in 6th NIDA/INVEST Meeting on International Trends and Needs in Drug Abuse Research at Scottsdale, Arizona, USA (June, 16-19th, 2006) & in College on Problems of Drug Dependence, 67rd Annual Scientific Meeting, Scottsdale, Arizona, USA  (June 18th  –22nd, 2006).
  • Appointed as member of selection committee for convening of Departmental promotion Committee meeting for filling the post of Assistant Director (Biochemistry), CCRAS, Deptt. of AYUSH , MOH & FW, Govt. of India,  April, 2006.
  • Chaired the 3rd scientific session on 3rd August of International Symposium on Forensic Science at Amity Institute of Advance Forensic Science Research and Training (1-4 August. 2007) Noida, UP, India.
  • Recipient of NIDA ISAM ( International Society of Addiction Medicine) Travel Award for presenting paper in 10th Annual Scientific Meeting of  ISAM at Cape Town, South Africa (Nov. 17th-20th, 2008).
  • Chaired the symposium on “ Substance Use disorder” of XVI National Conference of the Indian Association for Social Psychiatry (28-30th Nov. 2008), AIIMS, New Delhi.
  • Chaired the Poster Session 5 of the International Conference of Translation Pharmacology and 41st Annual Conference of Indian Pharmacological Society, (18-20th Dec. 2008), AIIMS, New Delhi.
  • Chaired the Scientific Session entitled “Health Effects, Screening and Biomarkers” In “14th World Conference on Tobacco or Health”, (8-12th March 2009), New Oberoi Hotel, Mumbai, India.  
  • Examiner Delhi University for Ph. D thesis in Biomedical Sciences, since 2009.
  • Was nominated as a member of Technical Advisory Committee for Tobacco testing Labs in India,   by Directorate General Health Services,   MOH Nirman Bhawan, New Delhi.” (since 2009). Resource development group, Extra mural research Division, Govt. of India, New Delhi, since 2010.
  • Project Reviewer: Council of scientific & Industrial Research, (CSIR), Human Resource development group, Extra mural research Division, Govt. of India, New Delhi, since  2010
  • Project Reviewer: Indian Council  of   Medical Research, Govt. of India, New Delhi, since  2010.
  • Reviewer for many Scientific Peer Reviewed National and International Journals.
  • Recipient of NIDA  International  Travel  award  for   participating and presentingpaper   in   “2010 NIDA International forum: Drug Abuse Research Policy and the Public Good & attending CPDD 72 Annual Scientist Meeting, at The Fairmont Scottsdale, Scottsdale, Arizona, USA (11-17th June, 2010).
  • Chaired the session “Forensic Toxicology” session in 10th Indo-Pacific Congress on Legal Medicine and Forensic Science on 27/10/2010 at Amity University, UP (25-30th. Oct. 2010).
  • Chaired the session  “ Alternate Matrices Regional Thoughts & Future Direction.” in “2nd International Conference on Medical Negligence in Medical Practice and on Recent Advances in Forensic Sciences, Medicine Toxicology at Hotel Riveriera De Goa, at  Goa ( 20-21st Feb., 2011).
  • Chaired the session of “Forensic Sciences, Antropology and Miscellaneous.” In 3rd International Conference on  Legal Medicine, Medical  Negligence in Medical Practice and on  Current Trends in Forensic Sciences, Medicine Toxicology  at  Hotel Ramada  Jaipur  (3rd - 5th Feb. 2012).
  • Delhi University  Ph.D viva Examiner in ‘BioMedical Sciences’ in the year 2012.
  • Doctoral Committe member of two Ph.D thesis (2012).
  • Member of the Selection   Committee in the interview board,  July 2012 session for admission to MSc- Ph.D combined Degree Program in Biomedical Sciences, Dr. B.R. Ambedkar Centre for Biomedical Research (ACBR), University of Delhi, Delhi.
  • Chaired the session of “Forensic Psychiatry, Toxicology.”In “4th  International Conference on Legal Medicine, Medical Negligence and Litigation in Medical Practice  4th International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology   at  Uday Samudra Hotel, Kovalum, Thiruvananthapuram, Kerala.  (25th- 27th Jan.2013).
  • Recipient of NIDA  International  Travel  award  for   participating and presenting paper  in 2013 NIDA International forum: Building International Collaborative Research on Drug Abuse and  attending CPDD 75th Annual Scientific Meeting,  at The  Hilton Bayfront Hotel, San Diego, CA, USA.  (14th - 20th June, 2013). 
  • Was one of the judge for the poster Session” Drugs and Toxicology” 11th Indo Pacific Association of Law, Medicine and Science Congress 2013 (INPALM 2013), at Shangri-La Hotel, Malaysia, Kuala Lumpur (5th- 10th Oct. 2013).
  • Was one of the expert on Substance abuse and a potential member  in WHO meeting of the guidelines development group for the World Health Organization "Guidelines on the management of opioid overdose" held at WHO headquarters in Geneva, Switzerland ( 19th- 20th Feb., 2014).
  • Chaired a session in Symposium on “Biological Research On Meditation/SKY” In Conference on Stress Reduction Skills: Scientific Update Dogra Hall (Auditorium) IIT Delhi, organized by Sri Sri Global Meditating Doctors Association & Department of Psychiatry  AIIMS ( August 30th-31st  2014).

 

  • Chaired a session of“ Future technology for sample collection in Forensics” InIAMLE-2015, 6th  International Conference on Legal Medicine, Medical Negligence and Litigation in Medical Practice and
     6th International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology at  Hotel Clarks, Khajuraho, Madhya Pradesh  ( Feb. 26th – 28th 2015).
  • Was  Recipient of NIDA  International  Travel  award  for   participating and presenting paper In 2015 NIDA International forum: Building International Collaborative Research on Drug Abuse at Arizona Biltmore Hotel, Phoenix, Arizona, USA.  (12th - 15th June, 2015).
  • Has been honored  with a  Certificate of appreciation as “Pioneer” in recognition of two decades of Building International Collaborative research on drug abuse on the 20th – Anniversary of NIDA International forum  in the 2015 NIDA International Forum meeting held  at Arizona Biltmore Hotel, Phoenix, Arizona, USA.  (12th - 15th June, 2015).
  • Appointed as a member of the  WHO   Expert Advisory Panel on Drug Dependence (Dependence Liability  Evaluation) :  World Health Organization, Geneva ,dated 31.08.2015
  • Has been honored with “Fellow” in “Forensic Toxicology” during  IAMLE  (Indian Association of Medico-legal Experts ) 2016 meeting held in Hyderabad 29th-31st Jan. 2016. 

·         Convener and Chaired the Symposium entitled “Role of non-nicotinic Acetylcholine receptors in nicotine dependence :Implications for smoking cessation treatment”  In, XXXIV Annual Meeting of Indian Academy of Neurosciences, National Brain research  Centre, Manesar, Gurgaon Dist. Haryana (Oct.19th -21st 2016).

·         Chaired the Symposium entitled Adoption of “E-Health and Novel Approaches in Prevention of Drug Abuse and Promotion of Mental Health” In, 22nd World Congress of Social Psychiatry (WASP2016),The Ashoka, New Delhi (30th Nov.- 4th  Dec.2016)

 

 

Others:

  1. Planned and Established the Drug Abuse Testing Laboratory at De-Addiction Centre of All India Institute of Medical Sciences, New Delhi, India.  This is the first time such a laboratory has been established in the country. The laboratory started functioning in June 1989.
  2. Officer- Incharge of Drug Abuse Testing , Preclinical Behavior and Biochemistry laboratories  at the National Drug Dependence Treatment Centre, AIIMS.  Drug Tests in body fluid includes (screening and confirmation) for: opioids (morphine, heroin, codeine, dextropropoxyphene, pentazocine, buprenorphine), opioid antagonists (naloxone, naltrexone), benzodiazepines (diazepam, oxazepam, chlordiazepoxide, nitrazepam), Barbiturates,  cannabinoids, anitihistaminics (pheniramine, promethazine), cocaine and nicotine (cotinine), inhalants (Toluene) . Every year approximately 26,000 drug tests (drugs of abuse) are screened in urine samples under my supervision. Moreover, every year approximately 29,000 routine biochemistry tests and 7000 hematological tests are carried out under my supervision
  3. Apart from post graduate teaching also imparting training of Drug Abuse Testing in body fluids to Laboratory personnel’s, Doctors, Nurses of various States of the country.
  4. Planned and Established a ‘Pre-clinical Behavior Laboratory in the department, for carrying out pre-clinical studies.  The laboratory started functioning in 1994.
  5. Chief Coordinator for organising National  workshop  on Treatment of Opiate Dependence  Disorder  with  Special  Focus  on Maintenance Programme, De-addiction Centre, AIIMS, New Delhi, (17-18th April, 2000).
  6. Membership of Scientific Societies: National:   Five;  International:   Six

 

 


 

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