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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Publications

PUBLICATIONS  

1.       Jaini R, Naruse T, Kanga U, Eikkawa E, Kaur G, Inoko H, Mehra NK.  Molecular diversity of the HLA-A*19 group of alleles in North Indians: possible oriental influence.  Tissue Antigens, 59:487-91, 2002.

 2.       Mehra NK, Kaur G, Jaini R.  Genetic diversity in the human major histocompatibility complex (MHC): lessons for vaccination approaches to HIV infection.  Community Genet 5:162-66, 2002.

 3.       Witt CS, Price P, Kaur G, Cheong KML, Christiansen FT, Mehra NK.  The common HLA-B8-DR3 haplotype in Northern India is distinct from that found in Europeans. Tissue Antigens. 60:474-80, 2002

 4.       Kaur G, Sarkar N, Bhatnagar S, Kumar S, Rapthap CC, Bhan MK, Mehra NK.  Paediatric celiac disease in India is associated with multiple DR3-DQ2 haplotypes.  Human Immunol 63: 677-682, 2002.

 5.       Sharma SK, Balamurugan A, Saha PK, Pandey RM, Mehra NK.  Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment.  Am J Respir Crit Care Med. 165:1-4, 2002.

 6.       Sharma SK, Mitra DK, Balamurugan A, Pandey RM, Mehra NK.  Cytokine polarization in miliary and pleural tuberculosis.  J Clin Immunol, 22:345-52,2002.

 7.       Panigrahi A, Agarwal SK, Kanga U, Guleria S, Bhowmik D, Dash SC, Gupta S, Tiwari SC, Mehta SN, Mehra NK.  Influence of HLA compatibility on renal graft survival using unrelated and cadaver donors in India.  Indian J Med Res, 115:158-164, 2002.

 8.         Deka R, Panigrahi A, Agarwal S, Guleria S, Dash SC, Mehta SN, Pandey RM,     Mehra NK. Influence of Pretransplant panel reactive antibodies on the post transplant sensitization status.  Transplantation Proceed, 34:3082-83, 2002.

 9.                  Chopra G.S, Diwan R.N, Mehra NK. Role of molecular typing in live related donor renal transplantation. Med J. Armed Forces India.  58;201-204,2002.

 10.             Witt C, Cheong K, Kaur G, Kanga U, Price P, Mehra NK, Sayer D, DeSantis D, Christiansen F.  HLA-B8 & DR 3 associated with IDDM in Europeans and Northern Indians but are on different haplotyes in these populations.  Tissue Antigens 59(Suppl): 21,2002.

 11.             Mehra Raj D, Kaushal RK, Sagar R, Kaur G, Malhotra S, Sharma K, Mitra DK, Mehra NK. Immunogenetic Analysis of Asian Indian Autistic Children.  Tissue Antigens  59 (Suppl) : 70-71, 2002.

 12.             Jaini R, Neolia S, Philip E, Kanga U, Kaur, Mehra NK. External Genetic Influences on MHC Diversity in Asian Indians. Tissue Antigens 59 (Suppl): 99, 2002.

 13.             Panigrahi A, Deka R, Mehra NK.  Clinical Relevance of Donor and Non-Donor specific anti HLA class-I Antibodies in live related Donor Renal Transplantation.  Tissue Antigens 59 (Suppl): 125, 2002.

 14.             Kanga U, Kumar A, Agrawal S, Kanokar SR, Mehra NK.  Heterogeneity of HLA-B27 group of allele in Asian Idians. Tissue Antigens  59 (Suppl): 131, 2002.

 15.             Mehra NK, Balamurugan A, Singh M, Mitra DK, Sharma SK, Sengupta U.  Pocket ‘1’ and ‘4’ residues in DRB1 molecules modulate immune response in mycobacterial infection.  Tissue Antigens 59 (Suppl): 135, 2002.

 16.             Kaur G, Sarkar N, Bhatnagar S, Kumar S, Rapthap CC, Bhan MK, Mehra NK. Paediatric celiac disease in India is associated with multiple DR3-DQ      2 haploytes.  Tissue Antigens 59 (Suppl) : 140, 2002.

 17.             Bhowmik D,  Dash SC, Guleria S, Panigrahi A, Gupta S,  Agarwal S,  Tiwari SC,  Mehta  SN and Mehra N.K. Spousal Renal Transplants: Implications in Developing Countries.  Transplantation Proceed 35:26-27,2003.

 18.             Basak U, Mitra DK, Panigrahi A, Guleria S, Agarwal S, Mehta SN, Dash SC, Mehra NK.  Clinical relevance of monitoring cytokine production following live donor renal transplantation.  Transplantation Proceed 35: 404-406, 2003.

 19.             Mehra NK, Kaur G.  MHC based vaccination approaches: progress and perspectives.  Expert Reviews in Molecular Medicine 5; 1-17, 2003. (http://www.expertreviews.org/03005957h.htm)

 20.             Kanga U, Jaini R, Kalia R,. Mehra NK.  Asian Indian Donor Marrow Registry: an alternate source of HLA matched donors for bone marrow transplantation.  In: Advances in Hematopoietic Stem Cell Transplantation eds: N.K. Mehra, O.P. Sood, published by Ranbaxy Science Foundation, Gurgaon, India p65-75, 2002.

 21.             Mehra NK, Singh M. Immunological mechanisms underlying relapse of original cancer: experience from autologous peripheral blood stem transplantation In: Advances in Hematopoietic Stem Cell Transplantation eds: N.K. Mehra, O.P. Sood, published by Ranbaxy Science Foundation, Gurgaon, India p109-117, 2002.

 22.             Kaur G, Rapthap CC, Mehra NK. Molecular analysis of chimerism following bone marrow transplantation In: Advances in Hematopoietic Stem Cell Transplantation eds: N.K. Mehra, O.P. Sood, published by Ranbaxy Science Foundation, Gurgaon, India p119-127, 2002.

 23.             Mehra NK. Opening Remarks In: Advances in Hematopoietic Stem Cell Transplantation eds: N.K. Mehra, O.P. Sood, published by Ranbaxy Science Foundation, Gurgaon, India p1-3, 2002.

 24.             Mehra NK.  Chapter on Transplantation Immunology and Clinical immunogenetics.  In: API Textbook of Medicine, 7th edition, editor-in-chief , Siddharth N. Shah, p23-30, 2003.

 25.             Mehra NK, Kaur G.  Genomics and immune response: opportunities and risks.  In Proceedings ICMR Symposium on Ethical, legal and social issues on Genomics, ICMR Publication, 2003.

Awards And Honours

Prof. N.K. Mehra received the chief of the Army Staff Award in February 2003.  He was elected ‘International Councillor for the prestigeous International Histocompatibility Workshops.  He continues to be the  'council member' of the International union of Immunological Societies (IUIS), Vice President of the Federation of Immunological Societies of Asia-Oceania (FIMSA) and as international councillor for the Australasian and South East Asian Tissue Typing Association (ASEATTA).  He serves as the 'Honorary Consultant' to the Armed Forces Medical Services (AFMS), a trustee of the Immunology Foundation India, member of the DBT Task Force on Human Resource Development, and Human Genetics and Genome analysis, member of the Scientific Advisory Committee of JALMA Institute for Leprosy, Agra and Institute of Cytology and Preventive Oncology (ICPO), New Delhi, member of the Advisory Board of the Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi.  member of the Board of Studies in Human Genetics of the Guru Nanak Dev University (GNDU), Amritsar, member of the ICMR Task Force on Immunology and of Project review committees of the ICMR, member of BHU Advisory Board for Molecular Genetics.

 

Prof. N.K. Mehra is on the Editorial Board of several prestigeous international journals: Microbes and Infection (Pasteur Institute, Paris), Tissue Antigens (Australia), Modern Rheumatology (Japan), International journal of Human Genetics (India), Journal of Clinical Immunology (USA).  He was invited Guest speaker at the inaugural scientific meeting of the Allergy and Immunology Society of Srilanka (ALSSL) and at the Braunschweig Streptococcal colloquium, Branschweig, Germany.  Professor Mehra is a member of the ethical, legal and social implications (ELSI) Committee of the Type 1 Diabetes Genetics consortium (T1DGC) of the NIH, Washington, USA.  He was elected as Vice President of the Indian Society of Organ Transplantation (ISOT). 

            Dr. Uma Kanga (Scientist II) serves as the ‘Councillor’ for the Australasian and South East Asian Tissue Typing Association (ASEATTA).

 

 Visiting Scientists 

 Dr Beverly Smith Keiling (USA), Dr Andreas D Keling (USA), Prof John Fahey (USA), Dr Jaspal Kaeda (UK), Dr Nikolai Petrovasky (Australia).  Dr. Sudhir Gupta (USA), Dr Sophie Caillat Zucman (France).

 Significant Events

 The department has established several new technologies including ELISA-PRA and Flow-PRA, for assessment of graft dysfunction following renal and bone marrow transplantation.   Chimerism analysis following BMT is also performed to assess the engraftment status of the recipient. These tests are very informative for post transplant monitoring. The services are offered for patient care purposes on routine basis.

 

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