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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Research

 

 

Year- 2021-2022

 

Funded projects

 

S. No.

Title of the project

1.

A Label Extension, Single Arm Multicentric Phase III Study To Assess The Efficacy And Safety Of Approved Product Stempeucel® In Patients With Critical Limb Ischemia Due To Buerger’s Disease

2.

Study of effectiveness of Maharishi Amrit Kalash on Breast cancer as  adjunct therapy along with Neo Adjunct Chemotherapy: An open Randomized controlled cl

 

3.

An observational study to evaluate the role of impaired NAD+ biosynthesis in calf skeletal muscle dysfunction in people with peripheral arterial disease,

4.

To check the feasibility of aortoplasty balloon catheter for endovascular occlusion of aorta- a cadaveric study

5.

Comparision of wire-guided lumpectomy versus sonographic hematoma guided lumpectomy in management of nonpalpable breast cancers. (Intramural Project)

6.

Development of aptamer-based assay for the diagnosis of breast tuberculosis (Breast TB), (AIIMS-THSTI collaborative project)

7.

“Study of heavy metals and trace elements (Arsenic, cadmium, chromium, and nickel, selenium, zinc, copper, lead, mercury, lead, cobalt) in gall bladder cancer and cholelithiasis patients.”. 

8.

“Study of heavy metals and trace elements (Arsenic, cadmium, chromium, and nickel, selenium, zinc, copper, lead, mercury, lead, cobalt) in Breast cancer and Benign breast disease  patients.”. 

9.

Clinical significance of Proteomics in liquid biopsy for Indian breast cancer women: An Exploratory stud

11.

To study the role of inflammatory markers in low pressure vs standard pressure laparoscopic cholecystectomy. RCT.

12.

Development of aptamer based assay for the diagnosis of breast tuberculosis

13.

Role of heavy metals in breast cancer.

14

Identification of factors predictive for weight loss after Bariatric Surgery: Building a Model for improving outcomes and maintaining weight loss

15

Transcendental meditation (TM) to reduce stress and enhance immunity of health care workers during COVID-19 pandemic: a randomized trial (TURMERIC trial)

16

Study to evaluate the presence of SARS-Cov-2 in different body fluids in SARSCOV- 2 positive/suspect patients undergoing laparoscopic, open surgery and endoscopic procedures

17

Study of Gut Microbiome in patients with gall bladder carcinoma -

18

LongTerm Outcome of Patients with Walled off Necrosis/Pseudocystof Pancreas in terms of Recurrence of Acute Pancreatitis, Fluid Collection and Functional Consequences following Internal Drainage by Laparoscopic or Endoscopic method

19

Prevalence of BRCA1/2 germline mutation in young Indian Women with triple negative breast cancer

20

RNA-seq based case-control study to identify alternatively spliced events in colorectal adenocarcinoma- Bioinformatics and genomics based study [2021-12417]

21

Metabolic resuscitation using early administration of ascorbic acid, thiamine and hydrocortisone in perioperative management of surgical patients with septic shock: A Randomized Controlled trial.

 

 

 

 Departmental projects including thesis

 

 

 

S.N

Title of the project

1

As Co-investigator "Perioperative blood glucose variability in non-diabetic patients with peritonitis undergoing emergency laparotomy: A propesctive observational study, Dr. Souwik, Deptt of Anesthesia, Institute Research Grants Rs.   5   laksh (Co-Inv, Dr. V.K. Bansal)

2

An Ambispective study to evaluate the outcomes of living kidney donors left with multiple renal arteries.

3

Follow up Study to Evaluate Correlation of Imaging and Operative findings with Clinical and Biochemical Outcome in Patients with Primary Hyperparathyroidism.

4

Indocyanine Green Fluorescence Imaging For Identifying And Assessing The Perfusion Of Parathyroid Glands During Thyroid Surgery- A Pilot Study.

5

Incidence of postoperative hypocalcemia after Indocyanine Green fluorescence guided v/s Conventional assessment of parathyroid function following total thyroidectomy  - A Randomised Controlled Trial.

6

Comparison of Early outcomes of interrupted double 'x' sutures vs continuous near far far near method for closure of abdominal wall incisions : A double blinded randomised control trial.

7

Incidence of Postoperative and Long Term Hypocalcemia After Indocyanine Green Fluorescence Guided V/S Conventional Assessment of Parathyroid Function Following Total Thyroidectomy- A randomised control trial.

8

A study to quantify the burden of insulin resistance in breast cancer women and its relation with other known prognostic and predictive factors of breast cancer.

9

Long term outcomes in breast cancer patients in terms of overall disease-free survival and locoregional recurrence (2 decades of surgical audit of breast cancer patients).

10

Surgical audit of Renal transplantation data of a single surgical unit over the last decade.

11

Three Arm Randomised Comparison of Laparoscopic Peritoneal Dialysis Catheter Insertion With or Without Omentectomy Versus Conventional Open Peritoneal Dialysis Catheter Insertion in Chronic Kidney Disease Stage 5 Patients in Terms of Catheter Malfunction and Post-Operative Complications.

12

The Anatomical basis of the Deep Inferior Epigastric Artery Perforator Flap and the Internal Mammary perforator flap: a CT Angiographic and Cadaveric Study.

13

Affect of preoperative management on peri operative events in patients with neuroendocrine tumors of the adrenal medulla- an ambispective cohort study.

14

The Anatomical basis of Thoracodorsal artery perforator flap and Lateral intercostal artery perforator flap and Anterior intercostal artery perforator flap: CT angiographic and cadaveric study.

15

Outcomes of difficult laparoscopic cholecystectomy- a prospective observational study.

16

Twenty year audit of breast cancer clinic.

17

BRCA mutation in young triple negative breast cancer patients.

18

A randomized control trial comparing mesh fixation with penetrating fixation device versus fibrin sealant during laparoscopic repair of ventral hernia

19

Evaluation of dual dye technique for sentinel lymph node biopsy in breast cancer: two arm open label parallel design non-inferiority randomized controlled trial 

20

To establish an algorithm for the management of axilla in patients with early operable breast cancer having clinically negative axilla

21

Neoadjuvant chemotherapy with short course radiotherapy for locally advanced rectal cancer: a pilot study

22

Impact of transcendental meditation ™ on acute and chronic stress among surgeons in training :  an open labelled randomized controlled trial.

23

Functional outcome of patients undergoing throracic surgery for benign pulmonary and pleural diseases: an ambispective cohort study

24

A study to explore the role of gamma synuclein as a potential biomarker in breast cancer.

25

Assessing effectiveness of a video-based intervention administered across a virtual platform on the existing knowledge, attitude and practices of breast cancer awareness and breast self-examination among literate women in the metropolitan city of Delhi: A Quasi-experimental community based interventional study

26

Outcomes following abdominal wall closure using MonoMax (poly 4 hydroxy butyrate) suture in emergency midline laparotomy: An ambispective study

27

Assessment of lateral thermal spread and tissue damage associated with the use of various electrosurgical devices

28

Assessment of transferabilitty of skills acquired on 3D HD and 4K HD endovision system to 2D HD endovision system: An ex-vivo study

29

Assessment of workload And Musculoskeletal Symptoms Among Minimal Access Surgeons – A Prospective Study

30

Patient reported outcome measures and objective assessment of achalasia cardia following Laparoscopic Heller’s myotomy and angle of His accentuation

31

Comparison of Quality of Life, cosmesis and oncological outcomes of skin sparing mastectomy with total breast reconstruction using autologous fat grafting versus skin sparing mastectomy with silicone implant reconstruction versus breast conservative therapy among patients with early breast cancer :  A Randomized controlled study

32

A study to validate the accuracy of the AIIMS modification of Paddington score in diagnosing phyllodes tumours, followed by a randomized control trial to evaluate the safety and efficacy of 1CM versus 2CM resection margin in phyllodes tumors

33

Knowledge and attitudes towards genetic counselling and testing in health care professionals and breast cancer patients

34

A randomized control trial to evaluate the safety and efficacy of 1cm Versus 2cm resection margin In Phyllodes tumours

35

Comparison of Quality Of Life, cosmesis and oncological outcomes of Skin Sparing Mastectomy with total breast reconstruction using autologous fat grafting versus skin sparing mastectomy with silicone implant reconstruction versus Breast Conservative Therapy among patients with Early Breast Cancer: A Randomized controlled trial 

36

Comparison of outcomes in patients with intraductal papilloma undergoing duct excision with 2.5 cm versus 5 cm length : A randomised controlled exploratory study

37

From RECIST to PERCIST: evolving considerations for PET response criteria in carcinoma breast

38

Validation of clinical examination with Doppler studies in the management of patients presenting with vascular disease: A Prospective study

39

Evaluation of role of platelet rich plasma in healing of chronic diabetic and peripheral arterial disease ulcers as compared to standard medical care: a randomized controlled trial

40

“Comparison of outcomes of Trans-oral vestibular and Axillo-breast approach for endoscopic hemithyroidectomy in patients with benign and indeterminate thyroid lesions- A randomized controlled trial.”

41

Role of indocyanine green in predictinglimb perfusion in comparison to standard methods incases of chronic limb threatening ischemia incorrelation with clinical progression

42

Identification of Sentinel Lymph node in Breast cancer by dual method both by Florescence and  methylene blue. As co PI

43

Use of Florescence and hematoma guided excision of the impalpable breast tumours as Co-PI

44

Comparison of quality of life between patients undergoing endoscopic thyroidectomy and conventional open thyroid Surgery

45

Development of aptamer-based assay for the diagnosis of breast tuberculosis (Breast TB)

46

Study of heavy metals and trace elements (Arsenic, cadmium, chromium, and nickel, selenium, zinc, copper, lead, mercury, lead, cobalt) in gall bladder cancer and cholelithiasis patients

47

To record the longterm outcome of patients    suffering from benign breast disease: an ambispective study

48

Impact of Transcendental Meditation (TM) on Acute and Chronic stress among surgeons in training: An open labelled randomized controlled trial”

49

Functional outcome of patients undergoing thoracic surgery for benign pulmonary and pleural diseases: An ambispective cohort study

50

Assessement of transferability of skills acquired on  3D HD and  4K HD endovision system to 2D HD endovision system : An exvivo study

51

Outcome of abdominal wall closure using poly 4 hydroxy butyrate suture in emergency midline laparotomy: An ambispective study

52

Assessing effectiveness of a video based intervention administered across virtual platform on the existing knowledge, attitude and practices of breast cancer awareness and breast self examination among literate women in metropolitan city of delhi: a quasi- experimental community based interventional study.

53

Assessment of lateral thermal spread and tissue damage associated with the use of various electrosurgical devices

54

Clinical applicability of whole body Low dose CT scan for detecting bone metastatis in breast cancer patients - a cross sectional study.

55

Comparison of 3D-CT volumetry and routine spirometry for prediction of post operative pulmonary function in benign lung diseases

56

Knowledge and attitude towards genetic counseling and testing in hereditary breast cancer in health care professionals and breast cancer patients

57

Impact of intraoperative microbreaks on Musculoskeletal symptoms and performance

Of surgical residents during minimal accessSurgical tasks in a simulated setting

58

Comparative Analysis between Different Stage Cancer Patients to Discover Novel Blood- Based Biomarkers for Detection of Early Stage Breast Cancer- A Pilot Study

59

A pilot study to compare interstitial multicatheter brachytherapy (IMB) versus volumetric modulated arc therapy (VMAT) for accelerated partial breast irradiation in early breast cancer: An adaptation, toxicity, and cosmesis comparison

60

Compare the standard vs low pressure laparoscopic cholecystectomy under deep neuromuscular block : RCT

61

To Study the clinical profile, investigations and outcome of patients undergoing parathyroidectomy : A retrospective and prospective experience.

62

To study the outcomes in patients with cholelithiasis following subtotal cholecystectomy.

63

A RCT to study the assess the efficacy of using uniform umbilical hygiene preoperatively to reduce incidence of umbilical port site complications in patients undergoing laparoscopic cholecystectomy.

64

To study etiology, clinical presentation and outcomes of patients with gastroduodenal perforation.

65

Correlation of pre and post operative surgical findings with clinical course in patients undergoing early laparoscopic cholecystectomy for asymptomatic gall stone disease.

66

To compare inflammatory markers in low pressure pneumoperitoneum with deep neuromuscular block vs standard pressure pneumoperitoneum among patients undergoing laparoscopic cholecystectomy for GSD:  A RCT

67

Use of prophylactic steroid to prevent hypocalcemia in patients undergoing thyroidectomy.

68

Analysis of patterns of neck trauma and its outcomes at level 1 trauma center: an ambispective observational study.

69

Fast track emergency lap cholecystectomy vs emergency laparoscopic cholecystectomy in index cases of acute calculus cholecystectitis patients presenting to emergency department – RCT.

70

To study causes of cancellation among patients scheduled for elective operations

71

To assess the functional outcomes in patients undergoing standardized laparoscopic mesh repair in small and medium ventral midline hernias

72

To assess the cost effectiveness of laparoscopic standardized laparoscopic mesh repair in ventral hernia

73

To study the complications of laparoscopic inguinal repair

74

Symptomatic outcomes in patients of asymptomatic gall stones after laparoscopic cholecystectomy

75

To study the concordance of TIRADS and the Bethesda System for reporting Thyroid Cytopathology with final histopathology in STN

76

To assess the functional outcomes in patients undergoing standardised mesh repair in small and medium ventral hernias

77

Telecommunication:Aneffectivetoolforearlyoperativefollowsupduringthe                  COVID

78

IllnessWellnessScale:AnewgradingsystemtoassesstheperformancestatusofCOVIDornon

79

To study causes of cancellation among patients scheduled for elective operations

80

To assess the functional outcomes in patients undergoing standardized laparoscopic mesh repair in small and medium ventral midline hernias

81

To assess the cost effectiveness of laparoscopic standardized laparoscopic mesh repair in ventral hernia

82

To study the complications of laparoscopic inguinal repair

83

Symptomatic outcomes in patients of asymptomatic gall stones after laparoscopic cholecystectomy

84

To study the concordance of TIRADS and the Bethesda System for reporting Thyroid Cytopathology with final histopathology in STN

85

To assess the functional outcomes in patients undergoing standardised mesh repair in small and medium ventral hernias

86

Telecommunication:Aneffectivetoolforearlyoperativefollowsupduringthe                  COVID

87

IllnessWellnessScale:AnewgradingsystemtoassesstheperformancestatusofCOVIDornon

88

To study causes of cancellation among patients scheduled for elective operations

89

Comparisonofmesotherapy(nonoperative)withsurgeryinmanagementofsuperficiallipomas.

90

Identification of Dietary factors predicting weight loss after Bariatric Surgery

91

Psychosocial factors affecting post-bariatric surgery weight loss: A Prospective

Observational Study

92

Optimal timing (Early vs Delayed) of Laparoscopic Cholecystectomy after

Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis: A

Randomized Control Trial.

93

To Study the Efficacy of Laparoscopically Delivered Transversus Abdominis Plane

Block for Postoperative Pain Control in Laparoscopic Ventral Hernia Repair – A

Placebo-Controlled Randomized Study

94

To compare the outcomes of Banded versus non-banded bariatric procedures -A

Prospective Randomized controlled trial.

95

To Evaluate and Compare Gastroesophageal reflux After Antral preserving and

Antral resecting Laparoscopic sleeve Gastrectomy for Morbidly Obese subjects: An

Ambispective Study

96

Omega Loop Gastric Bypass (Mini Gastric Bypass) versus Roux-en-Y Gastric

Bypass for the resolution of TYPE- II Diabetes Mellitus in Obese Subjects: An

Ambispective Study

97

Impact of Concomitant Hiatal Hernia Repair (HHR) on GERD-Q Score in Patients

Undergoing Laparoscopic Sleeve Gastrectomy for Obesity: A Prospective

Observational Study.

98

Hem-O-Lok Versus Endoscopic Stapler For Securing Base Of Appendix During

Laparoscopic Appendectomy: An Exploratory Randomized Controlled Trial

99

To compare inflammatory markers in low-pressure pneumoperitoneum with deep

neuromuscular block versus standard pressure pneumoperitoneum among patients

undergoing laparoscopic cholecystectomy for gallstone disease: A Randomized

Control Trial

100

Outcome of abdominal wall closure using poly 4 hydroxy butyrate suture in emergency midline laparotomy: An ambispective study

101

Assessment of transferability of skills acquired on  3D HD and  4K HD endovision system to 2D HD endovision system: An ex-vivo study

102

Impact of Transcendental Meditation (TM) on Acute and Chronic stress among surgeons in training: An open labelled randomized controlled trial

103

Mesh fixation with penetrating fixation device versus fibrin sealant during laparoscopic repair of ventral hernia: A double blind randomised control trial

104

Neoadjuvant Chemotherapy with Short Course Radiotherapy for Locally Advanced rectal cancer: A Pilot Study

105

Early Versus Delayed Laparoscopic Cholecystectomy in Moderate and Severe Acute Biliary Pancreatitis: A Randomised Controlled trial (ELCAP trial)

106

Questionnaire Based Survey of Musculoskeletal Dysfunction among General Surgeons and Comparison of Muscle Activity and Fatigue among Expert and Novice Surgeons during Laparoscopic Surgery using Surface Electromyography

107

Comparison of Early outcomes of Interrupted Double 'X' suture vs Continuous Near Far Far Near method for closure of abdominal wall incisions : A Double Blinded Randomised Control Trial

108

To study the usefulness of pre-operative USG guided  FNAC in avoiding radical surgery in patients with  gallbladder wall thickness or polyp associated with gall stone disease

109

Effect of yoga therapy on quality of life in patients undergoing laparoscopic incisional and ventral hernia repair- A randomised control trial

110

Short term and long term outcomes following laparoscopic and open donor nephrectomy : An ambispective comparative study

111

Study To Evaluate The Predictors Of Outcome In High Grade Blunt Liver Trauma

112

To study the correlation between pre-operative pain threshold measured using Quantitative Sensory Testing with post-operative pain scores using Visual Analogue Score in patients with laparoscopic groin hernia repair – A case control study

123

A prospective study to evaluate the restoration of abdominal wall dynamics in patients with incisional hernia following laparoscopic IPOM plus repair in comparison to healthy controls using surface EMG

124

Incidence of postoperative and long term Hypocalcemia after Indocyanine Green fluorescence guided vs Conventional assessment of parathyroid function following total thyroidectomy

125

Study to develop an objective scoring system to grade the difficulty of laparoscopic cholecystectomy

126

Long term outcomes in breast cancer patients in terms of overall disease-free survival and locoregional recurrence (2 decades of surgical audit of breast cancer patients)

127

A study to quantify the burden of Insulin Resistance in Breast Cancer Women and its relation with other known prognostic and predictive factors of Breast Cancer

128

Surgical audit of Renal transplantation data of a single surgical unit over the last decade

129

Assessment of Amphiregulin and CRISPLD1 as visceral adipose tissue derived modulators of cardiovascular health in obesity.

13

Optimal timing (Early vs Delayed) of Laparoscopic Cholecystectomy after endoscopic retrograde Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis: A Randomized Control Trial.

131

To study the effectiveness of laparoscopically delivered transversus abdominis plane block for postoperative pain control in laparoscopic ventral hernia repair - a placebo controlled randomized study

132

To determine the best non-invasive marker or a combination of them correlate the most with liver biopsy in extent of fibrosis in morbidly obese patients with non-alcoholic fatty liver disease undergoing bariatric surgery.

133

A randomised controlled study to assess the efficacy of using uniform umbilical hygiene preoperatively to reduce incidence of umbilical port site complications in patients undergoing laparoscopic cholecystectomy.

134

Impact of Concomitant Hiatal Hernia Repair on Gerd Q Score in Patients Undergoing Laparoscopic Sleeve Gastrectomy for Obesity: A Prospective Observational Study.

135

Omega loop gastric bypass (mini gastric bypass) versus Roux-en-Y gastric bypass for resolution of type-II diabetes Mellitus in obese subjects: A Prospective Randomized controlled trial

136

Investigation of the involvement of plasma membrane ATP binding transporter A1 (ABCA1) mediated insulin resistance.

137

Molecular characterization of transfer RNA derived RNA fragments and Expression of Mitochondrial fusion proteins in Non-Alcoholic fatty liver disease.

138

Stapled versus concurrent stapled and hand-sewn anastomosis in small intestine surgery: An exploratory randomized controlled trial

139

End to side versus side to side anastomosis with Ligation of vein distal to anastomosis for proximal arteriovenous fistula surgery: An exploratory randomized controlled trial.

140

Polymeric Clip versus Endoscopic Stapler for securing base of appendix during laparoscopic appendectomy: An exploratory randomized controlled trial.

 

 

 

 

 

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