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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Dr B Dhawan

Dr. Benu Dhawan

Professor

Department of Microbiology

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Dr. Benu Dhawan graduated in Medicine from Government Medical College, Patiala, in 1987. She obtained her MD (Microbiology) degree from the Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh in 1993. She joined the All India Institute of Medical Sciences, New Delhi in the year 1994. She is presently an  Additional Professor  in  the Bacteriology, Anaerobic & Mycoplasma division of the Department of Microbiology.

Research Focus:

Diagnostic Microbiology, Molecular Epidemiology and Antimicrobial Resistance with special reference to Staphylococcus aures, Enterococcus faecalis, Enterococcus faecium , Genital Mycoplasmas and Chlamydia trachomatis,

Lab Research Focus

My research area is diverse and encompasses work in three different areas that includes basic and applied aspects of Medical Microbiology. First, I am conducting studies evaluating the clonal distribution and mechanisms of antimicrobial resistance of both Hospital and Community acquired Methicillin resistant Staphylococcus aureus and Vancomycin resistant Enterococci.  Second, I am involved with development and clinical evaluation of a Real-Time PCR assay for detection of Chlamydia trachomatis and genotyping of these strains. Third, I am evaluating the activities of antimicrobial agents against genital mycoplasmas for formulation of guidelines for empirical treatment of patients with Sexually Transmitted Infections.

Research Guidance ( Chief Guide)

               Awarded

Under Submission
Ph.D 2 2
M.D. /M.S. 2 1

Ongoing Research Projects as Chief investigation

  1. Development and clinical evaluation of a real time PCR assay for detection of Chlamydia trachomatis in Indian women with infertility. (Indian Council of Medical Research)
  2. Molecular characterization of clinical isolates of Vancomycin and High level Gentamicin Resistant Enterococcus faecium and Enterococcus faecalis.(Indian Council Medical Research)

Publications

Research papers published : 94

      Cumulated citation index (CI)-860                  Cumulated Impact Factor (IF) : 232

      Chapter in Books                    : 1

 

Selected Publications

Methicillin Resistant Staphylococcus aureus

  • Gadepalli R, Dhawan B, Kapil A, Sreenivas V, Jais M, Gaind R, Chaudhry R, Samantaray JC, Udo EE. Clinical and molecular characteristics of nosocomial meticillin-resistant Staphylococcus aureus skin and soft tissue isolates from three Indian hospitals. J Hosp Infect. 2009 Nov;73(3):253-63
  • Dhawan B, Gadepalli R, Kapil A. In vitro activity of daptomycin against Staphylococcus aureus and vancomycin-resistant Enterococcus faecium isolates associated with skin and soft tissue infections: first results from India. Diagn Microbiol Infect Dis. 2009 Oct; 65(2):196-8.
  • Gadepalli R, Dhawan B, Mohanty S, Kapil A, Das BK, Chaudhry R, Samantaray JC.Mupirocin Resistance in Staphylococcus aureus in an Indian Hospital. Diagn Microbiol Infect Dis. 2007May; 58(1):125-127.
  • Gadepalli R,  Dhawan B,  Mohanty S, Kapil A, Das BK, Chaudhry R. Evaluation of different methods for detecting methicillin resistance in Staphylococcus aureus. Natl Med J India 2006; 19(4): 236.
  • Dhawan B, Rao C, Udo EE, Gadepalli R. Vishnubhatla S, Kapil A. Emergence if Methicillin Resistant Staphylococcus aureus SCCmec V in an India Hospital: Dissemination of Epidemic clones of Sequence Type (ST) 22,  ST 772 and ST 36 (Submitted to Diagn Microbiol Infect Dis)
  • Genital Mycoplasmas and Chlamydia trachomatis 
  • Dhawan B, Malhotra N, Sreenivas V, Rawre J, Khanna N, Chaudhry R, Mittal S. Prevalence of Ureaplasma serovars and their antimicrobial susceptibility in patients of infertility and genital tract infections.  Indian J Med Res. (In-press).
  • Ghosh A, Dhawan B, Chaudhry R, Vajpayee M, Sreenivas V.Genital Mycoplasmas and Chlamydia trachomatis infections in treatment Naïve HIV-1 infected adults. Indian J Med Res. 2011 Dec; 134(6) :960-6.
  • Gupta V, Dhawan B, Khanna N, Agarwal N, Bhattacharya SN, Sreenivas V, Chaudhry R. Detection and biovar discrimination of Ureaplasma urealyticum in Indian patients with genital tract infections. Diagn Microbiol Infect Dis. 2008 Jan; 60(1):95-7.
  • Pandey A, Dhawan B, Gupta V, Chaudhry R , Deorari AK. Clinical significance of airways colonization with Ureaplasma urealyticum in premature (<34 wk) neonates.  Indian J Med Res. 2007 May; 125(5):679-84.
  • Dhawan B, Gupta V, Khanna V, Singh M, Chaudhry R. Evaluation of the diagnostic efficacy of PCR for Ureaplasma urealyticum infection in Indian adults with symptoms of genital discharge. Jpn J Infect Dis 2006; 59(1):57-8.
  • Chlamydia trachomatis Infection in Infertile Women in North India: Diagnostic efficacy of an in-house Real-Time PCR assay (Submitted to Indian J Med Res)

Nosocomial Infections and Multidrug-Resistant Organisms

  • Dhawan B, Gadepalli R, Rao C, Kapil A, Sreenivas V. Decreased susceptibility to vancomycin in methicillin-resistant Staphylococcus aureus: a 5 year study in an Indian tertiary hospital. J Med Microbiol. 2010 Mar; 59 (Pt 3):375-6.
  • Dhawan B, Gadepalli R, Kapil A. In vitro activity of daptomycin against Staphylococcus aureus and vancomycin-resistant Enterococcus faecium isolates associated with skin and soft tissue infections: first results from India. Diagn Microbiol Infect Dis. 2009 Oct; 65(2):196-8. 
  • Gadepalli R,Dhawan B, Sreenivas V, Kapil A,Ammini AC, Chaudhry R. A Clinico-Microbiological Study of Diabetic Foot Ulcers in an Indian Tertiary Care Hospital. Diabetes Care 2006 Aug;29(8):1727-32
  • Gadepalli RS, Dhawan B, Mohanty S, Kapil A, Das BK, Chaudhry R Incidence of Inducible Clindamycin Resistance in Clinical Isolates of Staphylococcus aureus. Indian J Med Research 2006 Apr; 123(4):571-3.
  • Dhawan B, Bonnet R, Shukla NK, Mathur P, Das BK,Kapil A.  Infection with an Extended- Spectrum beta-Lactamase-Producing Strain of Serratia marcescens following tongue Reconstruction J Clin Microbiol. 2003; 14 (5):2233-4. 
  • Chandel DS, Chaudhry R, Dhawan B, Pandey A, Dey AB. Drug resistantSalmonella   enterica serotype paratyphi A in India. Emerg. Infect. Dis. 2000; 6(4): 420-421. 

 Anaerobic Infections

Joshy L, Chaudhry R, Dhawan B. Detection and characterization of Clostridium difficile from patients with antibiotic-associated diarrhoea in a tertiary care hospital in North India. J Med Microbiol. 2009 Dec;58(Pt 12):1657-9.

Mathur P, Chaudhry R, Dhawan B, Kumar L. Anaerobic Bacteremia in-patients with Hematologic Malignancies. Med Pediatr Oncol. 2002; 38(2): 147.

Dhawan B, Chaudhry R and Sharma N.  Incidence of Clostridium difficile infection: a prospective study in an Indian hospital. J Hosp Infect.  1999; 43: 275-280.

Diagnostic facilities developed 

  • Diagnostic  facilities for detection of Methicillin Resistant Staphylococcus aureus
  • Pulsed Field Gel Electrophoresis & SCCmec typing facility for Staphylococcus aureus
  • Molecular diagnostic facilities for detection of Vancomycin resistant Enterococci and their virulence determinants
  • Pulsed Field Gel Electrophoresis for Vancomycin Resistant Enterococci
  • Culture and Molecular diagnostic facilities for detection of Genital Mycoplasmas and Chlamydia trachomatis.
  • Antimicrobial  Susceptibility testing of Genital Mycoplasmas

International Awards and Honours

  1.   Congress Scholarship by the German foundation for International Development (DSE), 1998.
  2.    Nominated as “2002 Woman of the Year” by the American Biographical Institute
  3.   Awarded the “2003 Certificate of Membership to the American Association for the Advancement of Science ’’
  4. Recipient of Honorable Mention to the ASM-UNESCO Train-the-Trainers Scholarship Program, 2008.

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