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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Dr. Pragyan Acharya

Left to right: K. David Raja, Dr. Pragyan Acharya, AkshayMunjal

 

Address: Room No. 3002,

                Teaching Block,

               AIIMS, New Delhi-29.

Phone:011- 26546431

Email id:dr.pragyan.acharyaATgmail.com

Social media links: https://in.linkedin.com/in/pragyan-acharya-40599b16

Academic Details:

Degree

Subject

University/ Institution

Year

Ph.D.

Biochemistry

Indian Institute of Science, Bangalore

2011

M.S.

Biological Sciences (specialization Biochemistry)

Indian Institute of Science, Bangalore

2004

B.Sc. (H)

Biochemistry

Sri Venkateswara College, Delhi University

2001

 

 

Positions held:

 

Position

Department

University/ Institution

Dates

Assistant Professor

Biochemistry

AIIMS, New Delhi

October 2015-present

Visiting fellow

NIAID

National Institutes of Health, USA

February 2012-October 2015

 

 

GRANTS AND FELLOWSHIPS:

  • 2016-DST Early Career Award
  • 2016 AIIMS- Intra Mural Grant
  • Grant for 2017 EMBO Global Exchange Lecture Course entitled Malaria Genomics and Public Health.

AWARDS AND HONORS

  • Fellows Award for Research Excellence 2015- sponsored by the NIH Scientific Directors, the Office of Intramural Training & Education and FelCom/NIH.
  • Fellowship in the Khorana Nirenberg Scholars Program (US-India Career Transition Award- sponsored by DBT, India and NIH, USA) 2011
  • Ranbaxy Science Scholar 2010
  • Integrated Ph.D. Fellowship by Indian Institute of Science: 2001-2009 

SOCIETY MEMBERSHIP

Indian Society of Translational Research

 

Research Focus of the Lab

The research focus of our laboratory is the identification of metabolite, protein and nucleic acid based biomarkers that have diagnostic or prognostic value in different diseases. At the moment, we are studying the following conditions specifically-

(1) Celiac disease- biomarker identification through proteomics approaches.

(2) Organ Failure in Acute-on-chronic liver failure: biomarker identification through metabolomics approaches.

(3) Severe P. falciparum and P. vivax malaria: A systems biology approach towards understanding pathogenesis and identifying metabolite biomarkers of severe disease.

When it is appropriate, the mechanisms of disease pathogenesis will also be explored.

 

List of Lab members (Including technicians and attendants)

1. K. David Raja, M.Sc. Student

2.AkshayMunjal, M.Sc. Student

3.Poornima Gola, Technician

 

Positions available currently:

  • 1 motivated JRF is required to work on the project titled “Investigating the association of Purine Salvage Pathway with Severe Malaria Outcomes”.
  • I am happy to consider short term trainees.

 

Key publications

 

Research Papers 

1. Acharya P, Chaubey S, Grover M, Tatu U. An Exported Heat Shock Protein 40 Associates with Pathogenesis-Related Knobs in Plasmodium falciparum Infected Erythrocytes. PLoS One. 2012;7(9):e44605. Epub 2012 Sep 7.

2. Acharya P*, Pallavi R*, Chandran S, Dandavate V, Sayeed SK, Rochani A, Acharya J, Middha S, Kochar S, Kochar D, Ghosh SK, Tatu U. Clinical proteomics of the neglected human malarial parasite Plasmodium vivax. PLoS One. 2011;6(10):e26623.  Epub 2011 Oct 20. PubMed PMID: 22028927; PubMed Central PMCID: PMC3197670.*These authors have contributed equally.

3. Acharya P*, Pallavi R*, Chandran S, Chakravarti H, Middha S, Acharya J, KocharS,  Kochar D, Subudhi A, Boopathi AP, Garg S, Das A, Tatu U. A glimpse into the clinical proteome of human malaria parasites Plasmodium falciparum    and    Plasmodium    vivax.    Proteomics    Clin    Appl.    2009 Nov; 3(11):1314-25. doi: *These authors have contributed equally.

Selected as “Editor’s Choice” in Science (2010) Vol. 327, pp 13.

4. Pallavi  R*,  Acharya  P*,  Chandran  S,  Daily  JP,  Tatu  U.  Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients. Malar J. 2010 Aug 19;9: 236. PubMed PMID: 20719001. *These authors have contributed equally.

 5. PesceER,  Acharya P, Tatu U, Nicoll WS, Shonhai A, Hoppe HC, Blatch GL. The Plasmodium falciparum heat shock protein 40, Pfj4, associates with heat shock protein 70 and shows similar heat induction and localisation patterns. Int J Biochem Cell Biol. 2008;40(12):2914-26. Epub 2008 Jul 12.

 

Reviews

1. Acharya P, Kumar R, Tatu U. Chaperoning a cellular upheaval in malaria: heat shock proteins in Plasmodium falciparum. MolBiochemParasitol. 2007 Jun;153(2):85-94.

 

Book Chapters

1. Duffy P E,  Acharya P and Oleinikov A. Cytoadherence of the Malaria Parasite. Encyclopedia of Malaria. Springer Publications. (Accepted 2014)

2. Acharya P, Grover M and Tatu  U.Systems  Biology  of   Malaria  in Encyclopedia of Systems Biology. Springer Publications. 2013.

 

 

1. K. David Raja, M.Sc. Student

 

I did my graduation from Deshbandhu College, DU. I am trying to establish plasma derived nucleic acids as a source of biomarkers in Acute Chronic Liver Failure (ACLF). My current hobby is playing football and reading comics.

 

2. Akshay Munjal, M.Sc. Student

I did my graduation from Deshbandhu College, DU. I am trying to establish appropriate biomarkers for celiac disease using proteomics. My hobby is gardening. My field of interests is protein expression, purification and interaction studies.

 

3. Poornima Gola: Technician

Poornima helps with the general running of the lab and participates in indenting for materials and organizing help for the lab. She likes to read.

 

 

 

 

 

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All India Institute of Medical Sciences

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Board Number : +91-11-26588500 / 26588700

Fax : +91-11-26588663 / 26588641

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