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All India Institute Of Medical Sciences, New Delhi
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Dr. Sujata Mohanty

Name

Dr. Sujata Mohanty

 

Designation

Professor

Department/Institute/University

Stem Cell Facility(DBT-Centre of  Excellence for Stem Cell Research), AIIMS, New Delhi

Email Id

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Honors/Awards

 

·         University Grant Commission (UGC) fellowship during Ph.D (1991).
·         Junior Investigator Prize for best paper (1997).
·         Post-Doctoral fellowship from Mount Sinai hospital, New York, USA (1998).
·         Award from International Society for Stem Cell Research, USA (three times).
·         AIIMS Excellence Award in recognition of notable published research work. (2012, 2014& 2015).
·         Bharat Jyoti Award from India International Friendship Society(2013).
·         Third price for poster presentation in 15thINDO-US Flow Cytometry Workshop on “STEM CELLS’’ , 2014.
·         ICMR International Fellowship (2014- 2015) for training at Kyoto Prefectural University of Medicine, Kyoto, Japan, in Stem Cells and Scaffolds.
·         Best paper award for poster presentation in 43rd Annual Conference of the Indian Immunology Society” (2017)

 

Professional Experience and Training relevant to the Project

 

     A.  Membership of the Technical Expert Groups and Consultancy

1

Member of  Institute Committee for Stem Cell Research

  • National Institute of Immunology, New Delhi
  • Institute of Liver & Billiary Sciences, New Delhi
  • DBT Representative at Apollo Hospital
  • Sri Ganga Ram Hospital, New Delhi
  • V. P. Chest Institute, New Delhi
  • National Brain Research Centre, Manesar
  • THSTI, Faridabad
  • IIT, Indore

2

Member: International Bodies

  • International Society for Cellular Therapy (ISCT)
  • International Society for Stem Cell Research (ISSCR)
  • Society of Biological Chemists (SBC)
  • Indian Immunology society
  • Indian Society of Nanomedicine
  • Indian Science Congress Association
  • Stem Cell Research Foundation of India
  • Cytometry Society of India

3

Member of Advisory Bodies

  • Core Committee for Stem Cell Donor Registry for Bone Marrow Transplant in India
  • Stem Cell Donor Registry, Ministry of
  • Science &Family Welfare, Govt. of INDIA
  • High Powered Committee by Ministry of Health and Family Welfare, Govt. of India
  • Brainstorming meeting on Biofabrication & 3D Bioprinting
  • Expert Group Committee- Limbal Stem Cell Transplantation- ICMR
  • Centre for induced pluripotent Stem Cell Research and Application (CiRA) –For collaboration
  • Investigating team of CDSCO-Dendritic Cell Vaccine Scandal
  • Department of Biotechnology Task Force on Bioengineering
  • DBT Expert Committee for Indo-Australian Career Boosting Gold Fellowships (IACBG-Fellowships)

4

Member- Research Grant Review Committee

  • Project Monitoring Committee (BIRAC), DBT
  • Biotechnology Career Advancement and Reorientation Program for Women Scientists (BioCare), DBT
  • Biotechnology Industry Research Assistance Council (BIRAC)
  • Indian Council of Medical Research, New Delhi
  • Department of Science and Technology, New Delhi
  • Council of Scientific and Industrial Research, New Delhi
  • Peer Review Committee- DRDO-Apollo Hospital, Hyderabad

 

5

Member- Journal Review Committee

  • Stem Cell Research Open library (SCROL)
  • Life Science                               
  • Journal of Biosciences              
  • Biomedical Research Journal   
  • Insights in Stem Cells
  • World Journal of Stem Cells
  • CEINCIA publishing group
  • Translational Surgery
  • Molecular and Cellular Biochemistry

6

Member- Editorial Committee

  • Journal- Current Trends in Stem cells and Regenerative Medicine (CTSR)
  • Jacobs Journal of Bone Marrow and Stem Cell Research
  • Scientific Reports, Nature publishing house
  • Stroke Research & Treatment

 

B. Publications

a. Published:  Research Papers: 99

                               :  Abstracts: 88

b. Submitted: 15

 

C. Patents (filed): 02

 

D.Book Chapters:03

          1.         Mohanty S (2016), Cellular Therapy for Ocular Diseases (pp467-478). ThirumurthyVelpandian, Pharmacology of Ocular Therapeutics- Springer Nature, New York. DOI 10.1007/978-3-319-25498-2

          2.         Mohanty S (2016), Regenerative Medicine. D. Prabhakaran, Tandon’s Textbook of Cardiology.(Under review)

          3.         Mohanty S (2016), Clinical trials of cardiac regeneration using adult stem cells: Current and future prospects, Regenerative Medicine: Laboratory to Clinic- Springer Nature (Under review)

 

 

List of Publications:

 

2017

 

  1. Evaluating the osteogenic potential of CHT/HAP/PCL biocomposites in bone tissue engineering: An in vivo study. Krishan Gopal Jain, Manisha Singh, Anupama Kakkar, Rajesh Malhotra, Vineeta Batra, Alok Ray, Balram Airan, Mohanty S.. International Journal Of Scientific Research (Accepted)https://www.worldwidejournals.com/international-journal-of-scientific-research (IJSR)//articles.php?val=MTA3NTE=&b1=673&k=169

     2. Bone Marrow stem cell therapy partially ameliorates pathological consequences of liver in mice expressing mutant α1-antitrypsin. Prakash Baligar, Veena Kochat, Shailendra K. Arindkar, Zaffar Equbal, Snehashish Mukherjee, Swati Patel, Perumal Nagarajan, Mohanty S, Jeffrey H. Teckman, Asok Mukhopadhyay  (2017Hepatology. Volume 65, Issue 4, pages 1319–1335, April 2017. https://www.ncbi.nlm.nih.gov/pubmed/28056498

    3. Hypoxia-mediated epigenetic regulation of stemness in brain tumor cells. Pankaj Prasad, Shivani Mittal, Mohanty S, Tapasya Srivastava.. Stem Cells, 2017STEM2621 (Accepted). https://www.ncbi.nlm.nih.gov/pubmed/28376560

            4. Differential Reduction of Reactive Oxygen Species by Human Tissue-Specific Mesenchymal Stem Cells from Different Donors Under Oxidative Stress.Paliwal Swati, Kakkar Anupama, Rinkey Sharma,Airan Balram Mohanty S (2017)Journal of BioSciences -D-16-00538R1                      (Accepted)

 

 

2016

 

5. Fabrication of transparent quaternized PVA/silver nanocomposite hydrogel and its evaluation as an antimicrobial patch for wound care systems. Bhowmick, S., Mohanty, S. & Koul, V. (2016). J Mater Sci: Mater Med (2016) 27: 160. doi:10.1007/s10856-016-5772-8.https://www.ncbi.nlm.nih.gov/pubmed/27638099

 6. Effect of Hypoxia on Stemness and Differentiation of Dental Pulp Derived Stem Cells.Anupama Kakkar, Puneet Sharma, Manimuthu Mani Sankar, OP Kharbanda, Mohanty S* IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) Volume 15, Issue 8 Ver. VII (August. 2016), PP 102-111, http://www.iosrjournals.org/iosr-jdms/papers/Vol15-Issue%208/Version-7/T150807102111.pdf

 7.Can Mesenchymal Stem Cell be used as an Additive Therapeutic Procedure for Fracture Healing in Facial Injuries??Ruchi Pathak Kaul, Sushma Sagar, Mohanty S, Subodh Kumar (2016). Journal of Dental and Oral Health;Volume 2 • Issue 4 • e106, http://scientonline.org/open-access/can-mesenchymal-stem-cell-be-used-as-an-additive-therapeutic-procedure-for-fracture-healing-in-facial-injuries.pdf

 8.     Feeder and bFGF free culture of human embryonic stem cells: Role of conditioned media from immortalized human feedersPooja Teotia, Mohanty S*, Shilpa Sharma, Balram Airan;c; Manuscript ID: IJMR_152015-0472(424-15) (Accepted).https://www.ncbi.nlm.nih.gov/pubmed/28474621

 9.     Evaluation of sterilization of contaminated donor corneas by Gamma irradiation. Himi Tripathi, Pratik Kumar, Deepika Gupta, Rebika Dhiman, SeemaSen, SeemaKashyap, Tapas Nag, GeetaSatpathi, Mohanty S*, RadhikaTandon. IOVS. Manuscript ID: IOVS-15-18223 (Accepted).

10. Hair and Skin derived Progenitor Cells: In Search of a Candidate Cell for Regenerative Medicine Anil Kumar, Mohanty S*, Sushmita Bose Nandy, Somesh Gupta, Binod K Khaitan, Shilpa Sharma, BalramBhargava, BalramAiran .Indian J Med Res. 2016 Feb;143(2):175-83.https://www.ncbi.nlm.nih.gov/pubmed/27121515

 11.   Report: Stem cell applications in neurological practice, an expert group consensusappraisal. Devi M G, Sharma A, Mohanty S, Jain N, Verma K, Padma M V, Pal P, Chabbra H S, Khadilkar S, Prabhakar S, Singh G. Ann Indian Acad Neurol2016;19:367-73. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980961/

 12. Evaluation of circulating haematopoietic progenitor cells in patients with Trauma Haemorrhagic shock and its correlation with outcomes.Kumar M, Bhoi S, Subramanian A, Kamal VK, Mohanty S, Rao D, Galwankar S. Int J Crit Illn In jSci 2016;6:56-60. https://www.ncbi.nlm.nih.gov/pubmed/27308251

 13. Long Term Preservation of Donor Corneas in Glycerol for Keratoplasty: Exploring New Protocols.HimiTripathi, ,ManzoorUl MehdiDeepika GuptaSeemaSenSeemaKashyap,Tapas Chandra NagManishaPurwarManjeetJassalAshwini K Agrawal, MohantyS*, Radhika Tandon. Br J Ophthalmol. 2016 Feb;100(2):284-90. http://bjo.bmj.com/content/early/2015/10/26/bjophthalmol-2015-306944

 

2015

14.   Stem Cells of the Hair Follicular Tissue: Application in Cell Based Therapy for Vitiligo. Kumar A, Mohanty S, Gupta S, Paulkhurana SM (2015) Hair Ther Transplant 5:132. doi:10.4172/2167-0951.1000132. https://www.omicsgroup.org/journals/stem-cells-of-the-hair-follicular-tissue-application-in-cell-based-therapyfor-vitiligo-2167-0951-1000132.php?aid=47699

15. Culture & differentiation of Mesenchymal Stem Cell into osteoblast on degradable biomedical composite scaffold: In vitro study.  Jain KG, Mohanty S, Ray AR, Malhotra R, Airan B. Indian J Med Res. 2015 Dec;142(6):747-58. https://www.ncbi.nlm.nih.gov/pubmed/26831424

 16.“An invention of thermo-responsive polymer surface, yielding cell sheet based regenerative therapies in cardiology and ophthalmology” Sawa Y , Cherian KM , Mohanty S , Ganesh JS , Abraham S Journal of Stem cells and Regenerative medicine.2015 JSRM Code: 011020700010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728217/

 17. Long Term Outcomes of Cultivated Limbal Epithelial Transplantation: Evaluation and Comparison of Results in Children and Adults Anita Ganger, M. Vanathi, Mohanty S , Radhika Tandon;;  BioMed Research International, vol. 2015, Article ID 480983, 6 pages, 2015. doi:10.1155/2015/480983. https://www.hindawi.com/journals/bmri/2015/480983/

 18. Efficacy of stem cell in improvement of left ventricular function in acute myocardial infarction - mi3 trial;Velu Nair, Hemant Madan, Sunil Sofat, ProsenjitGanguli, M.J. Jacob, Rajat Datta, Prashant Bharadwaj, R.S. Sarkar, A.J. Pandit, Soniya Nityanand, Pravin K. Goel, Naveen Garg, Sanjay Gambhir, Paul V. George ,Sunil Chandy, Vikram Mathews, Oomen K. George, K.K. Talwar, Ajay Bahl, Neelam Marwah, Anish Bhatacharya, Balram Bhargava, Balram Airan, Mohanty S, Chetan D. Patel, Alka Sharma,Shinjini Bhatnagar, A. Mondal, Jacob Jose, A. Srivastava; IJMR, 2015 ;142(2):165-74. https://www.ncbi.nlm.nih.gov/pubmed/26354213

 19. Enhanced reprogramming efficiency and kinetics of induced pluripotent stem cells derived from human duchenne muscular dystrophy; PoojaTeotia, Mohanty S*, Madhulika Kabr, Sheffali Gulati, Balram Airan; PLOS Currents: Muscular Dystrophy; Version 1. PLoSCurr. 2015 September 3; 7. https://www.ncbi.nlm.nih.gov/pubmed/26579330

20. Role of Human Cardiac biopsy derived Conditioned Media in modulating Bone Marrow derived Mesenchymal Stem Cells towards Cardiomyocyte like Cells; Anupama Kakkar, Mohanty S*, BalramBhargava, BalramAiran; July,2015; Journal of Practice of Cardiovascular Sciences; 2015; 1(2):150-155. http://www.j-pcs.org/article.asp?issn=2395-5414;year=2015;volume=1;issue=2;spage=150;epage=155;aulast=Kakkar

21.   . Evaluation of serum granulocyte colony stimulating factors in patients admitted with Trauma Haemorrhagic shock and their correlation with immediate outcome.Manoj Kumar, Sanjeev Bhoi, S. Arul Selvi, Vineet Sharma, Mohanty S, D. N. Rao Int. J. Adv. Res. Biol.Sci. 2(7): (2015): 107–114. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901827/

 22. Interleukin (IL)-8 is an early predictor of mortality following trauma hemorrhagic shock ; Manoj Kumar, D.N Rao, Mohanty S, Arul Selvi S, SanjeevBhoi; Int. J. Adv. Res. Biol.Sci. 2(7): (2015): 12–20. https://www.omicsonline.org/proceedings/interleukin-il8-early-predictor-of-mortality-following-trauma-hemorrhagic-shock-29282.html

 23. Strategies for faster detachment of corneal cell sheet using micropatterned thermo-responsive matrices.Sharda Nara,   Shibu Chameettachal,  Swati Midha, Himi Singh,  Radhika Tandon,  Mohanty S,  Sourabh Ghosh   J. Mater. Chem. B, 2015,3, 4155-4169. http://pubs.rsc.org/en/Content/ArticleLanding/2015/TB/c5tb00350d#!divAbstract

 

2014

 24. Detection of homing-in of stem cells labeled with technetium-99m hexamethylpropyleneamineoxime in infarcted myocardium after intracoronary injection. Patel CD, Agarwal S, Seth S, Mohanty S*, Aggarwal H, Gupta N. Indian J Nucl Med. 2014 Oct;29(4):276-7. doi: 10.4103/0972-3919.14264. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228599/

 25.   Fibroblast Growth Factor-2 alone as an efficient inducer for differentiation of human bone marrow mesenchymal stem cells into dopaminergic neurons.Sushmita Bose, Mohanty S*, Manisha Singh, MadhuriBehari, BalramAiran Journal of Biomedical Science 2014, 21:83  doi:10.1186/s12929-014-0083-1 https://www.ncbi.nlm.nih.gov/pubmed/25248378

 26.   Intravenous autologous bone marrow mononuclear cell therapy for ischemic stroke: A multi-centric, randomized trial. Kameshwar Prasad, Alka Sharma, Ajay Garg, Mohanty S, Shinjini Bhatnagar, Sharat Johri, KK Singh, Velu Nair, Ravi Sarkar, Sankar Gorthi, Kaukab Hassan, Sudesh Prabhakar, Neelam Marwaha, Niranjan Khandelwal, Usha Misra, Jayantee Kalita, and Soniya Nityanand. Stroke/2014/007028D-AR1. https://www.ncbi.nlm.nih.gov/pubmed/25378424

 27.   Autologous stem cell transplantation in refractory Asherman's syndrome: A novel cell based therapy. Neeta SinghMohantyS*, Tulika SethMeenakshi ShankarSruthi Bhaskaran,  Sona Dharmendra. J Hum Reprod Sci. 2014 Apr-Jun; 7(2): 93–98. https://www.ncbi.nlm.nih.gov/pubmed/25191021

 28. Stem cells in Neurological Diseases: Indian perspective. Ashu Bhasin, Padma Srivastava MV, Rohit Bhatia, Senthil Kumaran, Mohanty S.J Stem Cell Res Ther 2014, 4:3 (http://dx.doi.org/10.4172/2157-7633.1000175). https://www.omicsonline.org/open-access/review-stem-cells-in-neurological-diseases-indian-perspective-2157-7633.1000175.php?aid=23627

 29. Effect of stem cells on renal recovery in rat model of partial unilateral upper ureteric obstruction. N. Sugandhi, M. Srinivas, S. Agarwala, D. K. Gupta, S. Sharma, A. Sinha, A. Dinda, S. MohantyPediatric surgery International, 2014. 30:233–238. https://www.ncbi.nlm.nih.gov/pubmed/24370792

 30.   Surface-Modified Electrospun Poly (e-Caprolactone) Scaffold With Improved Optical Transparency and Bioactivity for Damaged Ocular Surface Reconstruction.Shweta Sharma, Deepika Gupta ,Mohanty S, ManjeetJassal, Ashwini K. Agrawal , RadhikaTandon. Invest Ophthalmol Vis Sci. 2014; 55:899–907. DOI:10.1167/ iovs.13-12727. https://www.ncbi.nlm.nih.gov/pubmed/24425860

 31.   5-Florouracil-loaded poly(lactic acid)-poly(caprolactone) hybrid scaffold: potential chemotherapeutic implant. Gupta KK, Pal N, Mishra PK, Srivastava P, Mohanty S, Maiti P. .J Biomed Mater Res A. 2014 Aug;102(8):2600-12. https://www.ncbi.nlm.nih.gov/pubmed/24038786

 

2013

32. Propitious role of Bone marrow-derived mononuclear cells in an Experimental Bile Duct Ligation model - Potential clinical implications in obstructive cholangiopathy. Shilpa Sharma, Mohanty S*, Prasenjit Das, Sidhartha Dutta Gupta, Lalit Kumar, evendra Gupta.. Pediatric surgery International, 2013 Jun;29(6):623-32. https://www.ncbi.nlm.nih.gov/pubmed/23604400

33. Depletion of CD200bulge stem cells in premature human gray hair follicles. Mohanty S*, Anil Kumar, Somesh Gupta. J Cutan Aesthet Surg. 2013 Apr-Jun; 6(2): 90–92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764768/

 34. Stem Cell Niche is Partially Lost during Follicular Plucking: A Preliminary Pilot Study.Kumar A, Gupta S, Mohanty S, Bhargava B, Airan B. Int J Trichology. 2013 Apr;5(2):97-100. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877484/

 35.   Extracted hair follicle outer root sheath cell suspension for pigment cell restoration in vitiligo.Kumar A, Mohanty S, Sahni K, Kumar R, Gupta SJ Cutan Aesthet Surg. 2013 Apr;6 (2):121-5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764761/

 36. Limbal Epithelial stem cells in Corneal Regeneration Shweta Sharma, M Vanathi, Mohanty S, RadhikaTondon.Delhi Journal of Opthalomology;2013; 24(1:43-50).http://www.djo.org.in/articles/24/1/Limbal-Epithelial-Stem-Cells-in-Corneal-Regeneration.html

 37.   TGF-beta1 contribues to cardiomyogenic like differentiation of human bone marrow Mesenchymal Stem Cells. Mohanty S, Sushmita Bose, KrishanGopal Jain, Balram Bhargava, Balram Airan.International Journal of Cardiology 2013 Feb 10;163(1):93-9. https://www.ncbi.nlm.nih.gov/pubmed/21903280

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