Department Of BioChemistry

Content Provider: Dr. P. Chattopadhyay on Dt. Dec 01, 1998

Members of the Faculty

	Dr. Subrata Sinha MD,PhD, Prof.
	Dr. Neeta Singh PhD, Prof.
	Dr. D.N. Rao PhD, Prof.
	Dr. Nibhriti Das PhD, Prof.
	Dr. Ranju Ralhan PhD, Prof.
	Dr. Shyam Chauhan PhD, Prof.
	Dr. M.R. Rajeshwari PhD,Addl. Prof.
	Dr. P. Chattopadhyay MD,PhD, Assoc.Prof.
	Dr. Kalpana Luthra PhD,Assoc. Prof.
	Dr. Alpana Sharma Asstt.Prof.
	Dr Kunzang Chosdol Asstt.Prof.
	Dr N.C Chandra Asstt.Prof. (Adhoc)

EMERITUS SCIENTIST :

Prof. Shail K. Sharma PhD, Emeritus Scientist, CSIR

ACTIVITIES

Teaching Research Specialised Laboratory Services

POST-DOCTORAL FELLOWS	STUDENTS
Tutors - 3 Research Associates - 11	PhD. - 27 MD - 6 MSc - 4 MBBS- 50 BSc (Hons.) Human Biology - 11

TEACHING ACTIVITIES

Lectures, tutorials, problem-based learning, case oriented approach and hands-on practical training in clinical chemistry for MBBS and BSc students
Lectures, seminars, journal clubs and detailed research technique oriented practical exercises for BSc, MSc, MD & PhD students
Dissertation for MSc and Thesis work for MD & PhD

SPECIALIZED LABORATORY SERVICES :

Protein electrophoresis
Serum Lactate Dehydrogenase isoenzymes
Gonadal function : Estradiol, Testosterone, Progesterone
Pituitary function : GH, FSH, LH, TSH, PRL
Tumour markers :betaHCG, PSA, CEA, AFP, Bcl2, Apoptotic Index, Telomerase
Immunological parameters : C3, C4, CRI, CH50, CIC
UP

RESEARCH ACTIVITIES :

UP

Research interests of Dr. Subrata Sinha, MD,PhD, Prof.

Tel:(91)-11-6593314 Fax:(91)-11-6862663

email : ssinha@aiims.ac.in
1. Genomic plasticity in tumours
2. Molecular Biology of glial and * tumourigenesis
3. Generation of potentially immunotherapeutic antibodies against target antigens from phage display libraries
UP

Research interests of Dr. Neeta Singh, PhD, Prof.

Tel:(91)-11-6594945 Fax:(91)-11-6862663

email : neeta@aiims.ac.in
1. Molecular aspcts of apoptosis and cloning of mRNA expressed in apoptosis
2. Telomeres and Telomerase in cancer
3. Chemical carcinogenesis
4. Signal transduction mechanism
5. Correlation between Hpv& tolerance activity in cervical carcinoma
UP

Research interests of Dr. D.N. Rao, PhD, Prof.

Tel:(91)-11-6593545 Fax:(91)-11-6862663

email :dnrao311@rediffmail.com , dnrao@aiims.ac.in
1. Developing novel delivery system for HIV and malaria vaccine
2. Development of novel adjuvants in vaccines
3. Development of reagents for Immunodiagnostic approach of infectious diseases
4. Role of T-regulatory cells in leprosy
UP

Research interests of Dr. Nibhriti Das, PhD, Prof.

Tel:(91)-11-6864851 ext. 3467 Fax:(91)-11-6862663

email : nibhriti@aiims.ac.in
1. Interaction of insectisides with complement system and related immune functions
2. Role of complement, complement receptors and immune complexes in health and disease
3. Atrial Natriuretic Peptide and signal transduction
UP

Research interests of Dr. Ranju Ralhan, PhD, Prof.

Tel:(91)-11-6593478 Fax:(91)-11-6862663

email : rralhan@aiims.ac.in
1. Genetic and molecular alterations in human oral precancerous and cancerous lesions
2. Genetic alterations in human esophageal cancer : Diagnostic/Prognostic implications
3. Identification of differentially expressed genes in oral tumourigenesis and in response to retinoid treatment
4. Mechanism of action of retinoids/receptors in chemoprevention of human oral squamous cell carcinoma
5. Mechanism of multidrug resistance in human oral cancer
6. Designing of novel heat sensitive natural lipid derived liposomes for encapsulation of anti-cancer drugs for targeted drug delivery
7. Alterations in the expression of Colligen, p53 and Retinoic acid receptor(RARbeta) in oral submucous fibrosis
UP

Research interests of Dr. M.R. Rajeswari, PhD, Addl. Prof.

Tel:(91)-11-6864851 ext.3416 Fax:(91)-11-6862663

email : mrraji@aiims.ac.in
1. Conformational aspects of protein, DNA and their interactions using biophysical and biochemical methods
2. Structure function relationship of porins of outer membrane in E.Coli., Acinetobacter baumanii., Aeromonas and Micbactrium chaloae.
3. The mechanism of action ofantibacerialdrugs Quinolones, (Nalidixic acid etc.,),,
4. Anti - cancer drugs and their interactions with DNA.
5. Protein folding - role of electrostatic forces, packing of residues etc.
6. Stability and appications of Oligonucleotides as therapeutics.
UP

Research interests of Dr. Shyam S. Chauhan, PhD, Prof.

Tel:(91)-11-6864851 ext 3272 Fax:(91)-11-6862663

email : chauhan@aiims.ac.in
1. Mechanism of regulation of gene expression of a lysosomal cysteine protease, Cathepsin L, by malignant transformation
2. Role of Cathepsin L protease in tumour invasion and metastatis
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Research interests of Dr. P. Chattopadhayay, MD, PhD, Assoc. Prof.

Tel:(91)-11-6864851 EXT.4270 Fax:(91)-11-6862663

email : not available
1. Glioma cell proliferation and differentiation with various genotoxic and differentiating agents : relationship to the effects of alterations of chromosome 17 tumour suppressor gene products
2. Effect of free radicals and chemotherapeutic agents on p53 positive and negative tumour cell lines under hypoxic conditions
  UP
  
  Research interests of Dr. Kalpana Luthra, PhD, Assoc. Prof.
  
  Tel:(91)-11-6593478 Fax:(91)-11-6862663
  
  email : kalpanal@medinst.ernet.in
  1. Apolipoproteins: Genomic polymorphism and phenotyping
  2. Oncogene expression in hormonally induced cell lines
  3. Complement regulatory proteins in renal diseases.
  UP
  
  Research interests of Prof. Shail K. Sharma, PhD, Emr. Scientist, CSIR
  
  Tel:(91)-11-6863621 Fax:(91)-11-6862663
  
  email : shailks@medinst.ernet.in
  1. Purification and characterization of the delta opiod receptor
  2. Development and differentiation of nervous system using monoclonal antibodies
  UP

�AIIMS , New Delhi,

Department Of BioChemistry

POST-DOCTORAL FELLOWS