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Dr. Neeta Singh Prof. & Head Dr. Neeta Singh received her Ph.D. in Biochemistry in 1976 from Delhi University, Delhi, India. She joined AIIMS as Associate Professor in 1987. She served a Post Doctoral Research Fellowship from 1979-1980 at Neurochemical Institute, Copenhagen, Denmark and from 1983-85 at Swiss Institute for Experimental Cancer Research, Switzerland. She was a Visiting Associate from 1992-93 at National Cancer Institute, USA under NIH Fogarty Program. She was awarded Danish Govt. Fellowship (DANIDA), Swiss Govt. Fellowship, ICRETT award of International Union against Cancer (UICC) in 1989 and 1997, UNDP award, Universitat/Witten award, Visiting Associateship of NIH Fogarty, USA, Fellowship of National Academy of Medical Sciences, India, membership of International Union against Cancer (UICC), American Association for Cancer Research, New York Academy of Sciences. She has distinguished herself in the field of cancer research and has made a significant contribution in understanding chemical carcinogenesis, ROS & signal transduction mechanisms, role of telomeres, telomerase, and HPV in cancer, impact of apoptosis in health and disease (cancer), experimental cancer therapeutics and prevention and chemoprevention, effect of non-ionizing Electro Magnetic Field (EMFs-Mobile phone) on human health. She has 150 research publications to her credit. Last 5 years publications: 1. Kar R, Sen S, Singh A, Sharma H, Kumar S, Duttagupta S, Singh N. Role of apoptotic regulators in human epithelial ovarian cancer. Cancer Biology and Therapy. 6(7); 1101 -05; 2007. 2. Sen S, Singh A, Pal A, Sharma C, Kar R, Singh N. Anticancer gene expression profile of curcumin identifies new therapeutic targets in squamous cell lung carcinoma in vitro. J. of Clin. Oncol. (Suppl.) 25 (18S): 18203; 2007. 3. Kuhar M, Imran S, Singh N. Celecoxib enhances the chemotherapeutic response of cisplatin and TNF-alpha in SiHa cells through ROS-mediated mitochondrial pathway. Intl. J. Biomedical Sciences. 3: 176-184; 2007. 4. Mishra YK, Mohopatra S, Avasthi DK, Kabiraj D, Lala MP, Pivin JC, Sharma H, Kar R, Singh N. Synthesis and characterization of gold and silica nanocomposites for preliminary study on the detection of ovarian cancer cells. Nanotechnology. 18: 345606-11; 2007 5. Kuhar M, Imran S, SinghN. Curcumin and quercitin enhance cisplatin mediated apoptosis in human laryngeal carcinoma Hep2 cells through the mitochondrial pathway. J. of Cancer Molecules. 3: 121-8; 2007. 6. Singh M, Sharma H and Singh N. Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway. Mitochondrion. 7: 367-373; 2007. 7. Singh N and Sharma H. Apoptosis mechanism-based in vitro screening of dietary antioxidant chemoprevention agent. Free Radical and Antioxidant in Health and Disease. Editors and Publishers PP Singh, S Gupta, M Barjatiya, SP Mamtha and D Adhikari, 2007. 8. Singh N. Apoptosis in health and disease modulation of apoptosis for therapy: An overview. Indian Journal of Clinical Biochemistry. Vol 22(2), 6-16, 2007. 9. Singh M and Singh N. Induction of apoptosis by hydrogen peroxide in HPV-16 positive cancer cell lines – Involvement of mitochondrial pathway. Mol. & Cellular Biochemistry. 310(1-2): 57-65, 2008. 10. Sharma H, Datta P, Singh A, Sen S, Bhardwaj NK, Kochupillai V and Singh N. Gene expression profiling in practitioners of Sudhershan Kriya. J. of Psychosomatic Research. 64(2): 213-18; 2008. 11. Sen S, Bushra A, Sharma H, Datta P, Dutta GP, Bal S, Kumar A, Singh N. Molecular profiling of genes in squamous cell lung carcinoma in Asian Indians. Life Sciences. 82: 772-9; 2008. 12. Sen S, Sharma C, Pal A, Kar R, Singh N. Multiple anticancer targets of chemopreventor Curcumin squamous cells lung carcinoma in vitro (Abst.). Eur. J. Cancer (Suppl.) 6:53; 2008. 13. Singh A, Singh N. HPV and cervical cancer pathogenesis. Proc. American. Assoc. Cancer Res. 49: 2008. 14. Sen S, Sharma C, Pal A, Kar R, Chattopadhyay, Singh N. Antioxidant activity of curcumin facilitates its cancer chemotherapeutic potential in squamous cell lung carcinoma in vitro. Annals of Oncology. 19 (Suppl. 8) 2008. 15. Singh M, Singh N. Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells. Mol Cell Biochem. 325 (1-2): 107-19; 2009. 16. Pathak S, Sharma C, Jayaram HN, Singh N. Apoptotic signaling induced by benzamide riboside: an in vitro study. Mol Cell Biochem. 328 (1-2): 67-73; 2009. 17. Singh A, Datta P, Jain SK, Bhatla N, Duttagupta S, Dey B, Singh N. Human papilloma virus genotyping, variants and viral load in tumors, squamous intraepithelial lesions, and controls in a north Indian population subset.. Intl. J. Gynecol. Cancer. 19 (9): 1642-8; 2009. 18. Pillai MR, Hariharan R, Janki Mohan Babu, Lakshmi S, Chiplunkar S V, Patkar M, Tongaonkar H, Dinshaw K, Jayshree RS, Reddy BKM, Siddiqui M, Soma Roychoudury, Baisakhi Saha, Abraham P, Manu Gnanamony, Peedicayil Abraham, John S, Ram TS, Bindu Dey, Sharma C, Jain SK, Singh N. Molecular variants of HPV-16 associated with cervical cancer in Indian Population. Intl. J. Cancer. 125(1):91-103; 2009. 19. Datta P, Bhatla N, Dar L, Patro AR, Gulati A, Kriplani A, Singh N. Prevalence of human papillomavirus infection among young women in North India. Cancer Epidemiol. 34(2): 157-61; 2010. 20. Pillai RM, Babu JM, Jissa VT, Lakshmi S, Chiplunkar SV, Patkar M, Tongaonkar H, Reddy KB, Chakka KN, Siddiqui M, Roychoudury S, Abraham P, Peedicayil A, Gnanamony M, Subashini J, Ram TS, Dey B, Singh N, Singh A, Jain SK, Jayshree RS. Regionwise distribution of hrHPV types in squamous cell carcinoma of the cervix in India. Intl.J.Gynaecol.Cancer. 20(6):1046-51 2010. 21. Kar R, Jayanth P, Sharma C, Chattopadyay P, Kumar S, Kumar L and Singh N.Treatment with Survivin siRNA augments cytotoxicity of Paclitaxel in primary ovarian cancer cells. Proceedings of American. Assoc. Cancer Res. 2010 22. Singh M and Singh N. Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells. Molecular Cell Biochemistry. 347(1-2):1-11; 2011.
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